Department of Structural Biochemistry
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High-yield expression, reconstitution and structure of the recombinant, fully functional glutamate transporter GLT-1 from Rattus norvegicus.
Journal of molecular biology Aug, 2005 | Pubmed ID: 16024041
Oligomeric structure of the carnitine transporter CaiT from Escherichia coli.
The Journal of biological chemistry Feb, 2006 | Pubmed ID: 16365043
A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus.
Science (New York, N.Y.) Jun, 2006 | Pubmed ID: 16763151
Assembly of the major light-harvesting chlorophyll-a/b complex: Thermodynamics and kinetics of neoxanthin binding.
The Journal of biological chemistry Sep, 2006 | Pubmed ID: 16803876
Heterologously expressed GLT-1 associates in approximately 200-nm protein-lipid islands.
Biophysical journal Nov, 2006 | Pubmed ID: 16950847
Structure and function of prokaryotic glutamate transporters from Escherichia coli and Pyrococcus horikoshii.
Biochemistry Oct, 2006 | Pubmed ID: 17042498
The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering.
Cell Nov, 2006 | Pubmed ID: 17110339
Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake.
The EMBO journal Jan, 2007 | Pubmed ID: 17203075
Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
Cell Feb, 2007 | Pubmed ID: 17289572
Structural insight into pre-B cell receptor function.
Science (New York, N.Y.) Apr, 2007 | Pubmed ID: 17431183
Revival of electron crystallography.
Current opinion in structural biology Aug, 2007 | Pubmed ID: 17723294
Rubisco in complex with Rubisco large subunit methyltransferase.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2009 | Pubmed ID: 19208805
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1.
Cell Mar, 2009 | Pubmed ID: 19249086
Oligomeric structure and functional characterization of the urea transporter from Actinobacillus pleuropneumoniae.
Journal of molecular biology Apr, 2009 | Pubmed ID: 19361419
Electron crystallography as a technique to study the structure on membrane proteins in a lipidic environment.
Annual review of biophysics , 2009 | Pubmed ID: 19416061
The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations.
Nature structural & molecular biology Nov, 2010 | Pubmed ID: 20935634
Structural characterization of polyglutamine fibrils by solid-state NMR spectroscopy.
Journal of molecular biology Sep, 2011 | Pubmed ID: 21763317
Real-space processing of helical filaments in SPARX.
Journal of structural biology Feb, 2012 | Pubmed ID: 22248449
Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308417
Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy.
Cellular and molecular life sciences : CMLS Oct, 2012 | Pubmed ID: 22643837
Membrane fusion intermediates via directional and full assembly of the SNARE complex.
Science (New York, N.Y.) Jun, 2012 | Pubmed ID: 22653732
Structure of the rigor actin-tropomyosin-myosin complex.
Cell Jul, 2012 | Pubmed ID: 22817895
Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2013 | Pubmed ID: 23251034
FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers.
Journal of cell science Apr, 2013 | Pubmed ID: 23444374
A syringe-like injection mechanism in Photorhabdus luminescens toxins.
Nature Mar, 2013 | Pubmed ID: 23515159
Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol.
Bioscience reports May, 2013 | Pubmed ID: 23548308
Gestalt-binding of tropomyosin on actin during thin filament activation.
Journal of muscle research and cell motility Aug, 2013 | Pubmed ID: 23666668
Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division.
Biological chemistry Nov, 2013 | Pubmed ID: 23787465
A facile method for preparation of tailored scaffolds for DNA-origami.
Small (Weinheim an der Bergstrasse, Germany) Jan, 2014 | Pubmed ID: 23861344
Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.
The Journal of biological chemistry Oct, 2013 | Pubmed ID: 23990465
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.
The Journal of biological chemistry Jan, 2014 | Pubmed ID: 24273164
The role of Cdc42 and Gic1 in the regulation of septin filament formation and dissociation.
eLife Nov, 2013 | Pubmed ID: 24286829
Modular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organization.
Molecular cell Feb, 2014 | Pubmed ID: 24530301
Mechanism of Tc toxin action revealed in molecular detail.
Nature Apr, 2014 | Pubmed ID: 24572368
Prebiotic cell membranes that survive extreme environmental pressure conditions.
Angewandte Chemie (International ed. in English) Aug, 2014 | Pubmed ID: 24953643
The pseudo GTPase CENP-M drives human kinetochore assembly.
eLife Jul, 2014 | Pubmed ID: 25006165
Structural identification of the Vps18 β-propeller reveals a critical role in the HOPS complex stability and function.
The Journal of biological chemistry Nov, 2014 | Pubmed ID: 25324549
Architecture and conformational switch mechanism of the ryanodine receptor.
Nature Jan, 2015 | Pubmed ID: 25470059
Structure of the F-actin-tropomyosin complex.
Nature Mar, 2015 | Pubmed ID: 25470062
Structure of mega-hemocyanin reveals protein origami in snails.
Structure (London, England : 1993) Jan, 2015 | Pubmed ID: 25482543
Exploring the stability limits of actin and its suprastructures.
Biophysical journal Dec, 2014 | Pubmed ID: 25517163
The Habc domain of the SNARE Vam3 interacts with the HOPS tethering complex to facilitate vacuole fusion.
The Journal of biological chemistry Feb, 2015 | Pubmed ID: 25564619
pH-regulated selectivity in supramolecular polymerizations: switching between Co- and homopolymers.
Chemistry (Weinheim an der Bergstrasse, Germany) Feb, 2015 | Pubmed ID: 25583049
Deciphering the tubulin code.
Cell May, 2015 | Pubmed ID: 26000474
Functional homologies in vesicle tethering.
FEBS letters Sep, 2015 | Pubmed ID: 26072291
Condensation agents determine the temperature-pressure stability of F-actin bundles.
Angewandte Chemie (International ed. in English) Sep, 2015 | Pubmed ID: 26245168
The role of Bni5 in the regulation of septin higher-order structure formation.
Biological chemistry Dec, 2015 | Pubmed ID: 26351911
Determinants of amyloid fibril degradation by the PDZ protease HTRA1.
Nature chemical biology Nov, 2015 | Pubmed ID: 26436840
An interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cells.
Cell Oct, 2015 | Pubmed ID: 26456113
Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster.
Open biology Feb, 2016 | Pubmed ID: 26911624
Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin.
Nature communications Apr, 2016 | Pubmed ID: 27095104
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution.
Nature 06, 2016 | Pubmed ID: 27324845
Membrane insertion of a Tc toxin in near-atomic detail.
Nature structural & molecular biology Oct, 2016 | Pubmed ID: 27571177
Haptoglobin.
Antioxidants & redox signaling May, 2017 | Pubmed ID: 27650279
Multivalent Rab interactions determine tether-mediated membrane fusion.
Molecular biology of the cell Jan, 2017 | Pubmed ID: 27852901
Electron Cryo-microscopy as a Tool for Structure-Based Drug Development.
Angewandte Chemie (International ed. in English) Mar, 2017 | Pubmed ID: 27860084
The mother of all actins?
eLife Dec, 2016 | Pubmed ID: 27996935
Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1-Ccz1.
Nature communications Jan, 2017 | Pubmed ID: 28051187
Retromer-driven membrane tubulation separates endosomal recycling from Rab7/Ypt7-dependent fusion.
Molecular biology of the cell Mar, 2017 | Pubmed ID: 28100638
Structure of the RZZ complex and molecular basis of its interaction with Spindly.
The Journal of cell biology Apr, 2017 | Pubmed ID: 28320825
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