John P. O'Bryan

Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel.

The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination.

Intersectin activates Ras but stimulates transcription through an independent pathway involving JNK.

The Ews/Fli-1 fusion gene switches the differentiation program of neuroblastomas to Ewing sarcoma/peripheral primitive neuroectodermal tumors.

N-type Ca2+ channels as scaffold proteins in the assembly of signaling molecules for GABAB receptor effects.

Analysis of the role of ubiquitin-interacting motifs in ubiquitin binding and ubiquitylation.

The U-box ligase carboxyl-terminus of Hsc 70-interacting protein ubiquitylates Epsin.

Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling.

Intersectin enhances huntingtin aggregation and neurodegeneration through activation of c-Jun-NH2-terminal kinase.

Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway.

The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition.

Intersecting pathways in cell biology.

Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src.

Intersectin 1 contributes to phenotypes in vivo: implications for Down's syndrome.

Intersectin 1 Enhances Cbl Ubiquitylation of Epidermal Growth Factor Receptor through Regulation of Sprouty2-Cbl Interaction.

Cardiac-specific expression of the tetracycline transactivator confers increased heart function and survival following ischemia reperfusion injury.