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Department of Pharmacology
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Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel.
Current biology : CB Jan, 2002 | Pubmed ID: 11790300
The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination.
Current biology : CB Jul, 2002 | Pubmed ID: 12121618
Intersectin activates Ras but stimulates transcription through an independent pathway involving JNK.
The Journal of biological chemistry Nov, 2003 | Pubmed ID: 12970366
The Ews/Fli-1 fusion gene switches the differentiation program of neuroblastomas to Ewing sarcoma/peripheral primitive neuroectodermal tumors.
Cancer research Feb, 2004 | Pubmed ID: 14973077
N-type Ca2+ channels as scaffold proteins in the assembly of signaling molecules for GABAB receptor effects.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15047708
Analysis of the role of ubiquitin-interacting motifs in ubiquitin binding and ubiquitylation.
The Journal of biological chemistry Aug, 2004 | Pubmed ID: 15155768
The U-box ligase carboxyl-terminus of Hsc 70-interacting protein ubiquitylates Epsin.
Biochemical and biophysical research communications Mar, 2005 | Pubmed ID: 15694383
Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling.
Molecular pharmacology Nov, 2006 | Pubmed ID: 16914641
Intersectin enhances huntingtin aggregation and neurodegeneration through activation of c-Jun-NH2-terminal kinase.
Human molecular genetics Aug, 2007 | Pubmed ID: 17550941
Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway.
Molecular and cellular biology Nov, 2007 | Pubmed ID: 17875942
The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition.
The Journal of biological chemistry May, 2009 | Pubmed ID: 19240029
Intersecting pathways in cell biology.
Science signaling , 2010 | Pubmed ID: 21156937
Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src.
Molecular pharmacology Oct, 2011 | Pubmed ID: 21778303
Intersectin 1 contributes to phenotypes in vivo: implications for Down's syndrome.
Neuroreport Oct, 2011 | Pubmed ID: 21876463
Intersectin 1 Enhances Cbl Ubiquitylation of Epidermal Growth Factor Receptor through Regulation of Sprouty2-Cbl Interaction.
Molecular and cellular biology Feb, 2012 | Pubmed ID: 22158968
Cardiac-specific expression of the tetracycline transactivator confers increased heart function and survival following ischemia reperfusion injury.
PloS one , 2012 | Pubmed ID: 22272284
University of Illinois at Chicago
Katy A. Wong1,
John P. O'Bryan1
1Department of Pharmacology, University of Illinois at Chicago
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