Adolfo Saiardi

Inositol pyrophosphates are required for DNA hyperrecombination in protein kinase c1 mutant yeast.

Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists.

Inositol pyrophosphates regulate endocytic trafficking.

Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions.

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice.

Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death.

Phosphorylation of proteins by inositol pyrophosphates.

Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases.

Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity.

Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects.

Extraction and analysis of soluble inositol polyphosphates from yeast.

Inositol pyrophosphates get the vip1 treatment.

Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event.

Inositol polyphosphate multikinase: metabolic architect of nuclear inositides.

Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells.

Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling.

Human ITPK1: a reversible inositol phosphate kinase/phosphatase that links receptor-dependent phospholipase C to Ca2+-activated chloride channels.

The mood stabilizer valproate inhibits both inositol- and diacylglycerol-signaling pathways in Caenorhabditis elegans.

Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups.

Are inositol pyrophosphates signalling molecules?

Inositol pyrophosphates and their unique metabolic complexity: analysis by gel electrophoresis.

Inositol pyrophosphates modulate hydrogen peroxide signalling.

Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release.

An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons.

Synthesis of InsP7 by the Inositol Hexakisphosphate Kinase 1 (IP6K1).

Inositol hexakisphosphate kinases promote autophagy.

The signaling role of inositol hexakisphosphate kinases (IP6Ks).

Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB.

IP6K gene identification in plant genomes by tag searching.

Inositol hexakisphosphate kinases induce cell death in Huntington disease.

Identification of an evolutionarily conserved family of inorganic polyphosphate endopolyphosphatases.

Influence of inositol pyrophosphates on cellular energy dynamics.

Cell signalling by inositol pyrophosphates.

How inositol pyrophosphates control cellular phosphate homeostasis?

Arginine transcriptional response does not require inositol phosphate synthesis.

Inositol pyrophosphates: between signalling and metabolism.

Modulation of inositol polyphosphate levels regulates neuronal differentiation.

Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation.

Analysis of Dictyostelium discoideum inositol pyrophosphate metabolism by gel electrophoresis.

Functions of inorganic polyphosphates in eukaryotic cells: a coat of many colours.

Inositol phosphates induce DAPI fluorescence shift.

Raman spectroscopy detection of phytic acid in plant seeds reveals the absence of inorganic polyphosphate.

Protein polyphosphorylation of lysine residues by inorganic polyphosphate.

A novel method for the purification of inositol phosphates from biological samples reveals that no phytate is present in human plasma or urine.

VIH2 Regulates the Synthesis of Inositol Pyrophosphate InsP8 and Jasmonate-Dependent Defenses in Arabidopsis.

Prometabolites of 5-Diphospho-myo-inositol Pentakisphosphate.

Fungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity.

Why always lysine? The ongoing tale of one of the most modified amino acids.

There is no 'Conundrum' of InsP6.

Developmental accumulation of inorganic polyphosphate affects germination and energetic metabolism in Dictyostelium discoideum.

The new world of inorganic polyphosphates.

Phosphate, inositol and polyphosphates.

Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence.

Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels.

Protein pyrophosphorylation: moving forward.

Eukaryotic Phosphate Homeostasis: The Inositol Pyrophosphate Perspective.

Importance of Radioactive Labelling to Elucidate Inositol Polyphosphate Signalling.

Has Inositol Played Any Role in the Origin of Life?

The inositol pyrophosphate synthesis pathway in Trypanosoma brucei is linked to polyphosphate synthesis in acidocalcisomes.

Microbial inositol polyphosphate metabolic pathway as drug development target.

IP3-4 kinase Arg1 regulates cell wall homeostasis and surface architecture to promote clearance of Cryptococcus neoformans infection in a mouse model.

Inositol Polyphosphate Kinases, Fungal Virulence and Drug Discovery.

Asp1 Bifunctional Activity Modulates Spindle Function via Controlling Cellular Inositol Pyrophosphate Levels in Schizosaccharomyces pombe.

IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis.

Screening a Protein Array with Synthetic Biotinylated Inorganic Polyphosphate To Define the Human PolyP-ome.

Inositol Phosphates Purification Using Titanium Dioxide Beads.

Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles.

Lithium and fluoxetine regulate the rate of phosphoinositide synthesis in neurons: a new view of their mechanisms of action in bipolar disorder.

Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the quantitative analysis of mammalian-derived inositol poly/pyrophosphates.

Crosstalk between Ras and inositol phosphate signaling revealed by lithium action on inositol monophosphatase in Schizophyllum commune.

Inositol Polyphosphate Multikinase (), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity.

The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export.

Harnessing C-labeled -inositol to interrogate inositol phosphate messengers by NMR.

Fungal Kinases With a Sweet Tooth: Pleiotropic Roles of Their Phosphorylated Inositol Sugar Products in the Pathogenicity of Present Novel Drug Targeting Opportunities.

ITPK1 and ITPK2 Have an Evolutionarily Conserved Phytic Acid Kinase Activity.

ITPK1 mediates the lipid-independent synthesis of inositol phosphates controlled by metabolism.

Dictyostelium discoideum as a Model to Study Inositol Polyphosphates and Inorganic Polyphosphate.

Development of a yeast model to study the contribution of vacuolar polyphosphate metabolism to lysine polyphosphorylation.

Cellular IP Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP Are Attenuated for Infection and Replication.

Inorganic polyphosphate in mammals: where's Wally?

Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis.

Effects of the putative lithium mimetic ebselen on pilocarpine-induced neural activity.

IP-SPX Domain Interaction Controls Fungal Virulence by Stabilizing Phosphate Signaling Machinery.

Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry.

MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia.

Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity.

Inositol phosphate kinases in the eukaryote landscape.

IP6K3 and IPMK variations in LOAD and longevity: Evidence for a multifaceted signaling network at the crossroad between neurodegeneration and survival.

Cytoplasmic cleavage of IMPA1 3' UTR is necessary for maintaining axon integrity.

A stable immature lattice packages IP for HIV capsid maturation.

ITPK1 is an InsP/ADP phosphotransferase that controls phosphate signaling in Arabidopsis.