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Roy Maimon

Department of Physiology and Pharmacology,
Sackler Faculty of Medicine,
Department of Physiology and Pharmacology, Sackler Faculty of Medicine

Tel Aviv University

BIOGRAPHY

During my PhD I have demonstrated that ALS-diseased muscles secrete toxic factors which facilitate motor neuron degeneration in early stages of ALS disease. Currently, as postdoc fellow, I test a new concept for treating neurodegeneration: ASO-dependent generation of new neurons by direct conversion from astrocytes in the adult nervous system. Ultimately this approach may open new era for treating neurodegenerative diseases.

Education:

Ph.D., Tel Aviv University

M.S., Tel Aviv University

B.S., Bar Ilan University

PUBLICATIONS

Spatial-specific functions in retrograde neuronal signalling.

Traffic (Copenhagen, Denmark) 07, 2017 | Pubmed ID: 28393448

miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non-Cell-Autonomous Mechanism in ALS.

The Journal of neuroscience : the official journal of the Society for Neuroscience 06, 2018 | Pubmed ID: 29773756

Muscle secretion of toxic factors, regulated by miR126-5p, facilitates motor neuron degeneration in amyotrophic lateral sclerosis.

Neural regeneration research Jun, 2019 | Pubmed ID: 30762002

Targeting the Sigma-1 Receptor via Pridopidine Ameliorates Central Features of ALS Pathology in a SOD1 Model.

Cell death & disease 03, 2019 | Pubmed ID: 30824685

Structural Principles in Robo Activation and Auto-inhibition.

Cell 04, 2019 | Pubmed ID: 30853216

CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling.

EMBO reports Mar, 2020 | Pubmed ID: 31919978

INSTITUTIONS

Tel Aviv University

JOVE ARTICLES

Axonal Transport of Organelles in Motor Neuron Cultures using Microfluidic Chambers System

Topaz Altman^*,1,

Roy Maimon^*,1,

Ariel Ionescu^*,1,

Tal Gradus Pery¹,

Eran Perlson^1,2

¹Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University,

²Sagol School of Neuroscience, Tel Aviv University

Neuroscience

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Roy Maimon

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Physiology and Pharmacology,Sackler Faculty of Medicine,Department of Physiology and Pharmacology, Sackler Faculty of Medicine

Tel Aviv University

Axonal Transport of Organelles in Motor Neuron Cultures using Microfluidic Chambers System

Department of Physiology and Pharmacology,
Sackler Faculty of Medicine,
Department of Physiology and Pharmacology, Sackler Faculty of Medicine