Lars Edvinsson

Comparison of the vasodilator responses of isolated human and rat middle meningeal arteries to migraine related compounds.

CaMKII and MEK1/2 inhibition time-dependently modify inflammatory signaling in rat cerebral arteries during organ culture.

CaMKII inhibition with KN93 attenuates endothelin and serotonin receptor-mediated vasoconstriction and prevents subarachnoid hemorrhage-induced deficits in sensorimotor function.

Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries.

Contractile Changes in the Vasculature After Subchronic Smoking: A Comparison Between Wild Type and Surfactant Protein D Knock-Out Mice.

Experimental inflammation following dural application of complete Freund's adjuvant or inflammatory soup does not alter brain and trigeminal microvascular passage.

Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion.

Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-Mediated Contractility via Activation of Focal Adhesion Kinase and Extracellular Regulated Kinase 1/2 in Cerebral Arteries from Rat.

New insights on pyrimidine signalling within the arterial vasculature - Different roles for P2Y2 and P2Y6 receptors in large and small coronary arteries of the mouse.

Improved assessment of outcomes following transient global cerebral ischemia in mice.

Enhanced Endothelin-1 Mediated Vasoconstriction of the Ophthalmic Artery May Exacerbate Retinal Damage after Transient Global Cerebral Ischemia in Rat.

Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat.

Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat.

Distribution of CGRP and its receptor components CLR and RAMP1 in the rat retina.

Distribution of CGRP and CGRP receptor components in the rat brain.

Cerebrovascular gene expression in spontaneously hypertensive rats.

Recognizing the role of CGRP and CGRP receptors in migraine and its treatment.

Board Walk - October 2017.

A novel multicolor flow-cytometry application for quantitative detection of receptors on vascular smooth muscle cells.

Cerebrovascular Gene Expression in Spontaneously Hypertensive Rats After Transient Middle Cerebral Artery Occlusion.

Perivascular neurotransmitters: Regulation of cerebral blood flow and role in primary headaches.

Headache advances in 2017: a new horizon in migraine therapy.

Increased endothelin-1-mediated vasoconstriction after organ culture in rat and pig ocular arteries can be suppressed with MEK/ERK1/2 inhibitors.

PACAP and its role in primary headaches.

Vascular and molecular pharmacology of the metabolically stable CGRP analogue, SAX.

CGRP as the target of new migraine therapies - successful translation from bench to clinic.

Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans.

MEK/ERK/1/2 sensitive vascular changes coincide with retinal functional deficit, following transient ophthalmic artery occlusion.

CGRP Antibodies as Prophylaxis in Migraine.

Vascular pathology of large cerebral arteries in experimental subarachnoid hemorrhage: Vasoconstriction, functional CGRP depletion and maintained CGRP sensitivity.

Role of CGRP in Migraine.

Board Walk - July 2019.

Does inflammation have a role in migraine?

Rimegepant oral disintegrating tablet for migraine.

The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology.

C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system.

Cellular distribution of PACAP-38 and PACAP receptors in the rat brain: Relation to migraine activated regions.

Calcitonin Gene-Related Peptide (CGRP) and Cluster Headache.

The distribution of oxytocin and the oxytocin receptor in rat brain: relation to regions active in migraine.

Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity.

Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion.

Serotonin and Neuropeptides in Blood From Episodic and Chronic Migraine and Cluster Headache Patients in Case-Control and Case-Crossover Settings: A Systematic Review and Meta-Analysis.

The effects of CGRP in vascular tissue - Classical vasodilation, shadowed effects and systemic dilemmas.

Oxytocin as a regulatory neuropeptide in the trigeminovascular system: Localization, expression and function of oxytocin and oxytocin receptors.

Differences in pituitary adenylate cyclase-activating peptide and calcitonin gene-related peptide release in the trigeminovascular system.

Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects.

Transcriptome profiling revealed early vascular smooth muscle cell gene activation following focal ischemic stroke in female rats - comparisons with males.

Oral rimegepant for migraine prevention.

Identifying New Antimigraine Targets: Lessons from Molecular Biology.

Myocardial perfusion recovery induced by an α-calcitonin gene-related peptide analogue.