Department of Clinical Experimental Research
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Comparison of the vasodilator responses of isolated human and rat middle meningeal arteries to migraine related compounds.
The journal of headache and pain Apr, 2014 | Pubmed ID: 24754925
CaMKII and MEK1/2 inhibition time-dependently modify inflammatory signaling in rat cerebral arteries during organ culture.
Journal of neuroinflammation May, 2014 | Pubmed ID: 24886705
CaMKII inhibition with KN93 attenuates endothelin and serotonin receptor-mediated vasoconstriction and prevents subarachnoid hemorrhage-induced deficits in sensorimotor function.
Journal of neuroinflammation Dec, 2014 | Pubmed ID: 25498987
Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries.
Basic & clinical pharmacology & toxicology Feb, 2016 | Pubmed ID: 26272341
Contractile Changes in the Vasculature After Subchronic Smoking: A Comparison Between Wild Type and Surfactant Protein D Knock-Out Mice.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco May, 2016 | Pubmed ID: 26508395
Experimental inflammation following dural application of complete Freund's adjuvant or inflammatory soup does not alter brain and trigeminal microvascular passage.
The journal of headache and pain , 2015 | Pubmed ID: 26512021
Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion.
The journal of headache and pain , 2015 | Pubmed ID: 26627709
Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-Mediated Contractility via Activation of Focal Adhesion Kinase and Extracellular Regulated Kinase 1/2 in Cerebral Arteries from Rat.
Basic & clinical pharmacology & toxicology Jul, 2016 | Pubmed ID: 26781487
New insights on pyrimidine signalling within the arterial vasculature - Different roles for P2Y2 and P2Y6 receptors in large and small coronary arteries of the mouse.
Journal of molecular and cellular cardiology 04, 2016 | Pubmed ID: 26827897
Improved assessment of outcomes following transient global cerebral ischemia in mice.
Experimental brain research 07, 2016 | Pubmed ID: 26914479
Enhanced Endothelin-1 Mediated Vasoconstriction of the Ophthalmic Artery May Exacerbate Retinal Damage after Transient Global Cerebral Ischemia in Rat.
PloS one , 2016 | Pubmed ID: 27322388
Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat.
Journal of molecular neuroscience : MN Mar, 2017 | Pubmed ID: 27933490
Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat.
PloS one , 2017 | Pubmed ID: 28323857
Distribution of CGRP and its receptor components CLR and RAMP1 in the rat retina.
Experimental eye research 08, 2017 | Pubmed ID: 28603014
Distribution of CGRP and CGRP receptor components in the rat brain.
Cephalalgia : an international journal of headache Jan, 2017 | Pubmed ID: 28856910
Cerebrovascular gene expression in spontaneously hypertensive rats.
PloS one , 2017 | Pubmed ID: 28880918
Recognizing the role of CGRP and CGRP receptors in migraine and its treatment.
Cephalalgia : an international journal of headache Jan, 2017 | Pubmed ID: 29020807
Board Walk - October 2017.
Cephalalgia : an international journal of headache Oct, 2017 | Pubmed ID: 29039695
A novel multicolor flow-cytometry application for quantitative detection of receptors on vascular smooth muscle cells.
PloS one , 2017 | Pubmed ID: 29084284
Cerebrovascular Gene Expression in Spontaneously Hypertensive Rats After Transient Middle Cerebral Artery Occlusion.
Neuroscience Dec, 2017 | Pubmed ID: 29102661
Perivascular neurotransmitters: Regulation of cerebral blood flow and role in primary headaches.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Jan, 2017 | Pubmed ID: 29251523
Headache advances in 2017: a new horizon in migraine therapy.
The Lancet. Neurology 01, 2018 | Pubmed ID: 29263007
Increased endothelin-1-mediated vasoconstriction after organ culture in rat and pig ocular arteries can be suppressed with MEK/ERK1/2 inhibitors.
Acta ophthalmologica Aug, 2018 | Pubmed ID: 29369532
PACAP and its role in primary headaches.
The journal of headache and pain Mar, 2018 | Pubmed ID: 29523978
Vascular and molecular pharmacology of the metabolically stable CGRP analogue, SAX.
European journal of pharmacology Jun, 2018 | Pubmed ID: 29653090
CGRP as the target of new migraine therapies - successful translation from bench to clinic.
Nature reviews. Neurology Jun, 2018 | Pubmed ID: 29691490
Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans.
Neuroscience 11, 2018 | Pubmed ID: 30336190
MEK/ERK/1/2 sensitive vascular changes coincide with retinal functional deficit, following transient ophthalmic artery occlusion.
Experimental eye research 02, 2019 | Pubmed ID: 30439349
CGRP Antibodies as Prophylaxis in Migraine.
Cell 12, 2018 | Pubmed ID: 30550780
Vascular pathology of large cerebral arteries in experimental subarachnoid hemorrhage: Vasoconstriction, functional CGRP depletion and maintained CGRP sensitivity.
European journal of pharmacology Mar, 2019 | Pubmed ID: 30653947
Role of CGRP in Migraine.
Handbook of experimental pharmacology , 2019 | Pubmed ID: 30725283
Board Walk - July 2019.
Cephalalgia : an international journal of headache 07, 2019 | Pubmed ID: 31246131
Does inflammation have a role in migraine?
Nature reviews. Neurology 08, 2019 | Pubmed ID: 31263254
Rimegepant oral disintegrating tablet for migraine.
Lancet (London, England) 08, 2019 | Pubmed ID: 31311675
The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology.
Pharmacology , 2019 | Pubmed ID: 31484177
C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system.
The journal of headache and pain Nov, 2019 | Pubmed ID: 31718551
Cellular distribution of PACAP-38 and PACAP receptors in the rat brain: Relation to migraine activated regions.
Cephalalgia : an international journal of headache 05, 2020 | Pubmed ID: 31810401
Calcitonin Gene-Related Peptide (CGRP) and Cluster Headache.
Brain sciences Jan, 2020 | Pubmed ID: 31935868
The distribution of oxytocin and the oxytocin receptor in rat brain: relation to regions active in migraine.
The journal of headache and pain Feb, 2020 | Pubmed ID: 32028899
Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity.
International journal of molecular sciences Feb, 2020 | Pubmed ID: 32079247
Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion.
Journal of molecular neuroscience : MN Jun, 2020 | Pubmed ID: 32086679
Serotonin and Neuropeptides in Blood From Episodic and Chronic Migraine and Cluster Headache Patients in Case-Control and Case-Crossover Settings: A Systematic Review and Meta-Analysis.
Headache 06, 2020 | Pubmed ID: 32293721
The effects of CGRP in vascular tissue - Classical vasodilation, shadowed effects and systemic dilemmas.
European journal of pharmacology Aug, 2020 | Pubmed ID: 32442540
Oxytocin as a regulatory neuropeptide in the trigeminovascular system: Localization, expression and function of oxytocin and oxytocin receptors.
Cephalalgia : an international journal of headache 10, 2020 | Pubmed ID: 32486908
Differences in pituitary adenylate cyclase-activating peptide and calcitonin gene-related peptide release in the trigeminovascular system.
Cephalalgia : an international journal of headache 10, 2020 | Pubmed ID: 32486909
Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects.
The journal of headache and pain Nov, 2020 | Pubmed ID: 33167864
Transcriptome profiling revealed early vascular smooth muscle cell gene activation following focal ischemic stroke in female rats - comparisons with males.
BMC genomics Dec, 2020 | Pubmed ID: 33297959
Oral rimegepant for migraine prevention.
Lancet (London, England) 01, 2021 | Pubmed ID: 33338436
Identifying New Antimigraine Targets: Lessons from Molecular Biology.
Trends in pharmacological sciences Apr, 2021 | Pubmed ID: 33495027
Myocardial perfusion recovery induced by an α-calcitonin gene-related peptide analogue.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology Jun, 2021 | Pubmed ID: 34089154
Jesper Peter Bömers1,2,
Sara Ellinor Johansson2,
Lars Edvinsson2,4,
Tiit Illimar Mathiesen1,3,5,
Kristian Agmund Haanes2
1Department of Neurosurgery, Rigshospitalet,
2Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet,
3Department of Clinical Medicine, University of Copenhagen,
4Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University,
5Department of Clinical Neuroscience, Karolinska Institutet
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