Sunny Xia

Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells.

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia.

SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion.

VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1.

Augmentation of Cystic Fibrosis Transmembrane Conductance Regulator Function in Human Bronchial Epithelial Cells via SLC6A14-Dependent Amino Acid Uptake. Implications for Treatment of Cystic Fibrosis.

Conversion of human and mouse fibroblasts into lung-like epithelial cells.

ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel.

An organoid model to assay the role of CFTR in the human epididymis epithelium.

A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients.

Perspectives on the translation of in-vitro studies to precision medicine in Cystic Fibrosis.

Generation of functional ciliated cholangiocytes from human pluripotent stem cells.

High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids.

Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function.