Guodong Cao

Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptotic DNA fragmentation in transient cerebral ischemia and in neuronal cultures.

Induction of caspase-activated deoxyribonuclease activity after focal cerebral ischemia and reperfusion.

Cloning and characterization of rat caspase-9: implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia.

Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria.

In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis.

Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia.

Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation.

Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death.

6-Hydroxydopamine induces dopaminergic cell degeneration via a caspase-9-mediated apoptotic pathway that is attenuated by caspase-9dn expression.

Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway.

TAT-mediated delivery of Bcl-xL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF.

Apoptosis inducing factor mediates caspase-independent 1-methyl-4-phenylpyridinium toxicity in dopaminergic cells.

Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: potential signaling mechanisms.

Signal transducers and activators of transcription 5 contributes to erythropoietin-mediated neuroprotection against hippocampal neuronal death after transient global cerebral ischemia.

Mild hypothermia diminishes oxidative DNA damage and pro-death signaling events after cerebral ischemia: a mechanism for neuroprotection.

Impaired DNA repair via the base-excision repair pathway after focal ischemic brain injury: a protein phosphorylation-dependent mechanism reversed by hypothermic neuroprotection.

Preconditioning suppresses inflammation in neonatal hypoxic ischemia via Akt activation.

Erythropoietin promotes neuronal replacement through revascularization and neurogenesis after neonatal hypoxia/ischemia in rats.

Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.

Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury.

Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling.

Calcium dysregulation induces apoptosis-inducing factor release: cross-talk between PARP-1- and calpain-signaling pathways.

HSP27: mechanisms of cellular protection against neuronal injury.

Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway.

Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia.

Enhanced oligodendrogenesis and recovery of neurological function by erythropoietin after neonatal hypoxic/ischemic brain injury.

Enhanced Delivery of Erythropoietin Across the Blood-Brain Barrier for Neuroprotection against Ischemic Neuronal Injury.

Heat shock proteins: cellular and molecular mechanisms in the central nervous system.

Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.

Ischemia-induced calpain activation causes eukaryotic (translation) initiation factor 4G1 (eIF4GI) degradation, protein synthesis inhibition, and neuronal death.

Phosphorylation of HSP27 by protein kinase D is essential for mediating neuroprotection against ischemic neuronal injury.

Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury.

GST P1, a novel downstream regulator of LRRK2, G2019S-induced neuronal cell death.

Mutant erythropoietin without erythropoietic activity is neuroprotective against ischemic brain injury.

Gene delivery with viral vectors for cerebrovascular diseases.

APE1 upregulation reduces oxidative DNA damage and protects hippocampal neurons from ischemic injury.

Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1.

Neuronal NAMPT is released after cerebral ischemia and protects against white matter injury.

The Role of Nicotinamide Phosphoribosyltransferase in Cerebral Ischemia.

bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.

Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury.

White matter injury in ischemic stroke.

APE1/Ref-1 facilitates recovery of gray and white matter and neurological function after mild stroke injury.

Inhibition of Endoplasmic Reticulum Stress is Involved in the Neuroprotective Effect of bFGF in the 6-OHDA-Induced Parkinson's Disease Model.

Stem cell therapies in age-related neurodegenerative diseases and stroke.

Laparoscopic versus open surgery for rectal cancer: A meta-analysis of classic randomized controlled trials and high-quality Nonrandomized Studies in the last 5 years.

Procalcitonin as a Biomarker for Malignant Cerebral Edema in Massive Cerebral Infarction.

Complement Complex C5b-9 Levels Are Associated with the Clinical Outcomes of Acute Ischemic Stroke and Carotid Plaque Stability.

Intracranial atherosclerotic disease.

MEPO promotes neurogenesis and angiogenesis but suppresses gliogenesis in mice with acute ischemic stroke.

Intracerebroventricular Delivery of Recombinant NAMPT Deters Inflammation and Protects Against Cerebral Ischemia.

Hyperglycemia promotes Snail-induced epithelial-mesenchymal transition of gastric cancer via activating ENO1 expression.

FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.

Immune-Inflammatory Parameters in COVID-19 Cases: A Systematic Review and Meta-Analysis.

Mining novel cell glycolysis related gene markers that can predict the survival of colon adenocarcinoma patients.

A Risk Prediction Model for Evaluating the Disease Progression of COVID-19 Pneumonia.

siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways.

Expression and Prognostic Significance of Metastasis-Associated Protein 1 in Gastrointestinal Cancer.

A 4-gene-based hypoxia signature is associated with tumor immune microenvironment and predicts the prognosis of pancreatic cancer patients.

FHL3 Contributes to EMT and Chemotherapy Resistance Through Up-Regulation of Slug and Activation of TGF/Smad-Independent Pathways in Gastric Cancer.

Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function.

Fenton/Fenton-like metal-based nanomaterials combine with oxidase for synergistic tumor therapy.

Integrative analysis of prognostic value and immune infiltration of spindle and kinetochore-associated family members in breast cancer.

Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.

Development and Validation of a Pyroptosis-Related Signature for Predicting Prognosis in Hepatocellular Carcinoma.

Establishment and Analysis of an Individualized Immune-Related Gene Signature for the Prognosis of Gastric Cancer.

Tumor-Derived Lactate Creates a Favorable Niche for Tumor Supplying Energy Source for Tumor and Modulating the Tumor Microenvironment.

Elevated Lipoprotein-Associated Phospholipase A2 Is Associated With Intracranial Atherosclerosis.

Microglia-mediated neuroinflammation and neuroplasticity after stroke.

An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain.

Editorial: Modulating microglia to enhance neuroplasticity for restoring brain function after stroke.

A Novel Needle Mouse Model of Vascular Cognitive Impairment and Dementia.

Systemic treatment with ubiquitin carboxy terminal hydrolase L1 TAT protein ameliorates axonal injury and reduces functional deficits after traumatic brain injury in mice.

SPAK inhibitor ZT-1a attenuates reactive astrogliosis and oligodendrocyte degeneration in a mouse model of vascular dementia.

Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation.