Department of Neurology
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Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptotic DNA fragmentation in transient cerebral ischemia and in neuronal cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2001 | Pubmed ID: 11425895
Induction of caspase-activated deoxyribonuclease activity after focal cerebral ischemia and reperfusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Jan, 2002 | Pubmed ID: 11807389
Cloning and characterization of rat caspase-9: implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism May, 2002 | Pubmed ID: 11973426
Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria.
Journal of neurochemistry Jun, 2002 | Pubmed ID: 12068075
In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2002 | Pubmed ID: 12097494
Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12200426
Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Oct, 2003 | Pubmed ID: 14526224
Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2004 | Pubmed ID: 15240811
6-Hydroxydopamine induces dopaminergic cell degeneration via a caspase-9-mediated apoptotic pathway that is attenuated by caspase-9dn expression.
Journal of neuroscience research Sep, 2004 | Pubmed ID: 15352222
Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Jun, 2005 | Pubmed ID: 15716857
TAT-mediated delivery of Bcl-xL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF.
Neurobiology of disease Feb, 2006 | Pubmed ID: 16140540
Apoptosis inducing factor mediates caspase-independent 1-methyl-4-phenylpyridinium toxicity in dopaminergic cells.
Journal of neurochemistry Sep, 2005 | Pubmed ID: 16156740
Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: potential signaling mechanisms.
Journal of neuroscience research May, 2006 | Pubmed ID: 16511866
Signal transducers and activators of transcription 5 contributes to erythropoietin-mediated neuroprotection against hippocampal neuronal death after transient global cerebral ischemia.
Neurobiology of disease Jan, 2007 | Pubmed ID: 17008107
Mild hypothermia diminishes oxidative DNA damage and pro-death signaling events after cerebral ischemia: a mechanism for neuroprotection.
Frontiers in bioscience : a journal and virtual library Jan, 2007 | Pubmed ID: 17127418
Impaired DNA repair via the base-excision repair pathway after focal ischemic brain injury: a protein phosphorylation-dependent mechanism reversed by hypothermic neuroprotection.
Frontiers in bioscience : a journal and virtual library Jan, 2007 | Pubmed ID: 17127426
Preconditioning suppresses inflammation in neonatal hypoxic ischemia via Akt activation.
Stroke Mar, 2007 | Pubmed ID: 17272774
Erythropoietin promotes neuronal replacement through revascularization and neurogenesis after neonatal hypoxia/ischemia in rats.
Stroke Oct, 2007 | Pubmed ID: 17702962
Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2007 | Pubmed ID: 17728442
Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury.
Stroke Nov, 2008 | Pubmed ID: 18723421
Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2008 | Pubmed ID: 19052195
Calcium dysregulation induces apoptosis-inducing factor release: cross-talk between PARP-1- and calpain-signaling pathways.
Experimental neurology Aug, 2009 | Pubmed ID: 19427306
HSP27: mechanisms of cellular protection against neuronal injury.
Current molecular medicine Sep, 2009 | Pubmed ID: 19860665
Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway.
Stroke Jan, 2010 | Pubmed ID: 19910549
Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2010 | Pubmed ID: 20133634
Enhanced oligodendrogenesis and recovery of neurological function by erythropoietin after neonatal hypoxic/ischemic brain injury.
Stroke May, 2010 | Pubmed ID: 20360553
Enhanced Delivery of Erythropoietin Across the Blood-Brain Barrier for Neuroprotection against Ischemic Neuronal Injury.
Translational stroke research Jun, 2010 | Pubmed ID: 20577577
Heat shock proteins: cellular and molecular mechanisms in the central nervous system.
Progress in neurobiology Oct, 2010 | Pubmed ID: 20685377
Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2011 | Pubmed ID: 21209210
Ischemia-induced calpain activation causes eukaryotic (translation) initiation factor 4G1 (eIF4GI) degradation, protein synthesis inhibition, and neuronal death.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22006312
Phosphorylation of HSP27 by protein kinase D is essential for mediating neuroprotection against ischemic neuronal injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2012 | Pubmed ID: 22357851
Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury.
Stroke; a journal of cerebral circulation May, 2012 | Pubmed ID: 22461332
GST P1, a novel downstream regulator of LRRK2, G2019S-induced neuronal cell death.
Frontiers in bioscience (Elite edition) Jun, 2012 | Pubmed ID: 22652643
Mutant erythropoietin without erythropoietic activity is neuroprotective against ischemic brain injury.
Stroke Nov, 2012 | Pubmed ID: 22984011
Gene delivery with viral vectors for cerebrovascular diseases.
Frontiers in bioscience (Elite edition) Jan, 2013 | Pubmed ID: 23276981
APE1 upregulation reduces oxidative DNA damage and protects hippocampal neurons from ischemic injury.
Antioxidants & redox signaling Nov, 2013 | Pubmed ID: 24180454
Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2014 | Pubmed ID: 24478369
Neuronal NAMPT is released after cerebral ischemia and protects against white matter injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Oct, 2014 | Pubmed ID: 25005877
The Role of Nicotinamide Phosphoribosyltransferase in Cerebral Ischemia.
Current topics in medicinal chemistry , 2015 | Pubmed ID: 26059356
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Molecular neurobiology 12, 2016 | Pubmed ID: 26687235
Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury.
International journal of biological sciences , 2016 | Pubmed ID: 26722220
White matter injury in ischemic stroke.
Progress in neurobiology Jun, 2016 | Pubmed ID: 27090751
APE1/Ref-1 facilitates recovery of gray and white matter and neurological function after mild stroke injury.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2016 | Pubmed ID: 27274063
Inhibition of Endoplasmic Reticulum Stress is Involved in the Neuroprotective Effect of bFGF in the 6-OHDA-Induced Parkinson's Disease Model.
Aging and disease Aug, 2016 | Pubmed ID: 27493838
Stem cell therapies in age-related neurodegenerative diseases and stroke.
Ageing research reviews Mar, 2017 | Pubmed ID: 27876573
Laparoscopic versus open surgery for rectal cancer: A meta-analysis of classic randomized controlled trials and high-quality Nonrandomized Studies in the last 5 years.
International journal of surgery (London, England) Mar, 2017 | Pubmed ID: 28087370
Procalcitonin as a Biomarker for Malignant Cerebral Edema in Massive Cerebral Infarction.
Scientific reports Jan, 2018 | Pubmed ID: 29343753
Complement Complex C5b-9 Levels Are Associated with the Clinical Outcomes of Acute Ischemic Stroke and Carotid Plaque Stability.
Translational stroke research Jun, 2019 | Pubmed ID: 30173313
Intracranial atherosclerotic disease.
Neurobiology of disease Apr, 2019 | Pubmed ID: 30439443
MEPO promotes neurogenesis and angiogenesis but suppresses gliogenesis in mice with acute ischemic stroke.
European journal of pharmacology Apr, 2019 | Pubmed ID: 30716313
Intracerebroventricular Delivery of Recombinant NAMPT Deters Inflammation and Protects Against Cerebral Ischemia.
Translational stroke research Dec, 2019 | Pubmed ID: 30820847
Hyperglycemia promotes Snail-induced epithelial-mesenchymal transition of gastric cancer via activating ENO1 expression.
Cancer cell international , | Pubmed ID: 31889896
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
Aging , | Pubmed ID: 31935687
Immune-Inflammatory Parameters in COVID-19 Cases: A Systematic Review and Meta-Analysis.
Frontiers in medicine , | Pubmed ID: 32582743
Mining novel cell glycolysis related gene markers that can predict the survival of colon adenocarcinoma patients.
Bioscience reports , | Pubmed ID: 32744303
A Risk Prediction Model for Evaluating the Disease Progression of COVID-19 Pneumonia.
Frontiers in medicine , | Pubmed ID: 33251226
siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways.
Frontiers in oncology , | Pubmed ID: 33282725
Expression and Prognostic Significance of Metastasis-Associated Protein 1 in Gastrointestinal Cancer.
Frontiers in oncology , | Pubmed ID: 33409150
A 4-gene-based hypoxia signature is associated with tumor immune microenvironment and predicts the prognosis of pancreatic cancer patients.
World journal of surgical oncology , | Pubmed ID: 33865399
FHL3 Contributes to EMT and Chemotherapy Resistance Through Up-Regulation of Slug and Activation of TGF/Smad-Independent Pathways in Gastric Cancer.
Frontiers in oncology , | Pubmed ID: 34150617
Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function.
Journal of neuroinflammation Aug, 2021 | Pubmed ID: 34454529
Fenton/Fenton-like metal-based nanomaterials combine with oxidase for synergistic tumor therapy.
Journal of nanobiotechnology , | Pubmed ID: 34656118
Integrative analysis of prognostic value and immune infiltration of spindle and kinetochore-associated family members in breast cancer.
Bioengineered , | Pubmed ID: 34845974
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
Bioengineered , | Pubmed ID: 35094634
Development and Validation of a Pyroptosis-Related Signature for Predicting Prognosis in Hepatocellular Carcinoma.
Frontiers in genetics , | Pubmed ID: 35140750
Establishment and Analysis of an Individualized Immune-Related Gene Signature for the Prognosis of Gastric Cancer.
Frontiers in surgery , | Pubmed ID: 35174205
Tumor-Derived Lactate Creates a Favorable Niche for Tumor Supplying Energy Source for Tumor and Modulating the Tumor Microenvironment.
Frontiers in cell and developmental biology , | Pubmed ID: 35646923
Elevated Lipoprotein-Associated Phospholipase A2 Is Associated With Intracranial Atherosclerosis.
Frontiers in neurology , 2022 | Pubmed ID: 35756924
Microglia-mediated neuroinflammation and neuroplasticity after stroke.
Frontiers in cellular neuroscience , 2022 | Pubmed ID: 36052339
An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain.
Journal of neuroinflammation Dec, 2022 | Pubmed ID: 36457126
Editorial: Modulating microglia to enhance neuroplasticity for restoring brain function after stroke.
Frontiers in cellular neuroscience , 2023 | Pubmed ID: 37426552
A Novel Needle Mouse Model of Vascular Cognitive Impairment and Dementia.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2023 | Pubmed ID: 37684030
Systemic treatment with ubiquitin carboxy terminal hydrolase L1 TAT protein ameliorates axonal injury and reduces functional deficits after traumatic brain injury in mice.
Experimental neurology Mar, 2024 | Pubmed ID: 38092186
SPAK inhibitor ZT-1a attenuates reactive astrogliosis and oligodendrocyte degeneration in a mouse model of vascular dementia.
CNS neuroscience & therapeutics Mar, 2024 | Pubmed ID: 38433018
Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation.
Journal of neuroinflammation Sep, 2024 | Pubmed ID: 39256783
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