Cassian Sitaru

Cicatricial pemphigoid differs from bullous pemphigoid and pemphigoid gestationis regarding the fine specificity of autoantibodies to the BP180 NC16A domain.

Autoantibodies to bullous pemphigoid antigen 180 induce dermal-epidermal separation in cryosections of human skin.

Subacute prurigo variant of bullous pemphigoid: autoantibodies show the same specificity compared with classic bullous pemphigoid.

Autoantibodies to type VII collagen mediate Fcgamma-dependent neutrophil activation and induce dermal-epidermal separation in cryosections of human skin.

A highly sensitive and simple assay for the detection of circulating autoantibodies against full-length bullous pemphigoid antigen 180.

Memory B cells specific for the NC16A domain of the 180 kDa bullous pemphigoid autoantigen can be detected in peripheral blood of bullous pemphigoid patients and induced in vitro to synthesize autoantibodies.

Autoreactive T cell responses in pemphigus and pemphigoid.

The autoantigen of anti-p200 pemphigoid is an acidic noncollagenous N-linked glycoprotein of the cutaneous basement membrane.

The 97-kDa (LABD97) and 120-kDa (LAD-1) fragments of bullous pemphigoid antigen 180/type XVII collagen have different N-termini.

Immunoblotting and enzyme-linked immunosorbent assay for the diagnosis of pemphigoid gestationis.

Development of an ELISA for the detection of autoantibodies to BP230.

Localized linear IgA disease induced by ampicillin/sulbactam.

Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid.

Downregulation of CXCR1 and CXCR2 expression on human neutrophils by Helicobacter pylori: a new pathomechanism in H. pylori infection?

Comparative analysis of methods for detection of anti-laminin 5 autoantibodies in patients with anti-epiligrin cicatricial pemphigoid.

Subclass distribution of type VII collagen-specific autoantibodies in patients with inflammatory bowel disease.

Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen.

Subepidermal blistering disease with autoantibodies to both the p200 autoantigen and the alpha3 chain of laminin 5.

IgG autoantibodies to type VII collagen and an exclusive IgG3 reactivity to the laminin alpha3 chain in a patient with an autoimmune subepidermal blistering disease.

Mechanisms of blister induction by autoantibodies.

[Blistering autoimmune dermatoses (II): therapy].

[Bullous autoimmune dermatoses (I): Pathogenesis and diagnosis].

Scarring autoimmune bullous disease in a Ugandan patient with autoantibodies to BP180, BP230, and laminin 5.

[Mucous membrane pemphigoid: IgG and IgA antibodies against the BP180 antigen].

[Anti-laminin 5 mucous membrane pemphigoid].

Immunoadsorption against two distinct epitopes on human type XVII collagen abolishes dermal-epidermal separation induced in vitro by autoantibodies from pemphigoid gestationis patients.

Generation and characterization of monoclonal antibodies against the intracellular domain of hemidesmosomal type XVII collagen.

Localisation of bullous pemphigoid antigen 180 (BP180) in cultured human keratinocytes: functionally relevant modification by calcium.

Induction of complement-fixing autoantibodies against type VII collagen results in subepidermal blistering in mice.

Autoantibodies from patients with BSLE inducing recruitment of leukocytes to the dermoepidermal junction and subepidermal splits in cryosections of human skin.

IgA pemphigus--occurrence of anti-desmocollin 1 and anti-desmoglein 1 antibody reactivity in an individual patient.

Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.

The relevance of the IgG subclass of autoantibodies for blister induction in autoimmune bullous skin diseases.

The alternative pathway of complement activation is critical for blister induction in experimental epidermolysis bullosa acquisita.

Experimental models of epidermolysis bullosa acquisita.

Immunopathology and molecular diagnosis of autoimmune bullous diseases.

Enzyme-linked immunosorbent assay using multimers of the 16th non-collagenous domain of the BP180 antigen for sensitive and specific detection of pemphigoid autoantibodies.

IgG4 autoantibodies induce dermal-epidermal separation.

Neonatal Fc receptor deficiency protects from tissue injury in experimental epidermolysis bullosa acquisita.

Bullous pemphigoid autoantibodies preferentially recognize phosphoepitopes in collagen XVII.

Subepidermal blistering induced by human autoantibodies to BP180 requires innate immune players in a humanized bullous pemphigoid mouse model.

Bullous pemphigoid: a prototypical antibody-mediated organ-specific autoimmune disease.

Transition from pemphigus foliaceus to bullous pemphigoid: intermolecular B-cell epitope spreading without IgG subclass shifting.

Autoimmunity against type VII collagen in inflammatory bowel disease.

Pathogenicity of IgG subclass autoantibodies to type VII collagen: induction of dermal-epidermal separation.

T cells are required for the production of blister-inducing autoantibodies in experimental epidermolysis bullosa acquisita.

Cross-reactivity of autoantibodies from patients with epidermolysis bullosa acquisita with murine collagen VII.

The neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases.

Metal sensitization precipitates skin blistering in epidermolysis bullosa acquisita.

Pemphigus vulgaris is the most common autoimmune bullous disease in Northwestern Romania.

Ectodomain shedding generates Neoepitopes on collagen XVII, the major autoantigen for bullous pemphigoid.

PI3Kβ plays a critical role in neutrophil activation by immune complexes.

Development of an ELISA for sensitive and specific detection of IgA autoantibodies against BP180 in pemphigoid diseases.

Why human pemphigoid autoantibodies do not trigger disease by the passive transfer into mice?

The flavonoid luteolin inhibits Fcγ-dependent respiratory burst in granulocytes, but not skin blistering in a new model of pemphigoid in adult mice.

Prevalence of collagen VII-specific autoantibodies in patients with autoimmune and inflammatory diseases.

Blocking Fcα receptor I on granulocytes prevents tissue damage induced by IgA autoantibodies.

Two Japanese cases of dermatitis herpetiformis associated each with lung cancer and autoimmune pancreatitis but showing no intestinal symptom or circulating immunoglobulin A antibodies to any known antigens.