Navin Varadarajan

Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity.

Substrate specificity of the Escherichia coli outer membrane protease OmpP.

Highly active and selective endopeptidases with programmed substrate specificities.

An engineered protease that cleaves specifically after sulfated tyrosine.

Construction and flow cytometric screening of targeted enzyme libraries.

Proteases that can distinguish among different post-translational forms of tyrosine engineered using multicolor flow cytometry.

A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis.

Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving.

Multi-copy genes that enhance the yield of mammalian G protein-coupled receptors in Escherichia coli.

Single-cell characterization of autotransporter-mediated Escherichia coli surface display of disulfide bond-containing proteins.

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire.