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Department of Chemical and Biomolecular Engineering
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Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity.
Proceedings of the National Academy of Sciences of the United States of America May, 2005 | Pubmed ID: 15867160
Substrate specificity of the Escherichia coli outer membrane protease OmpP.
Journal of bacteriology Jan, 2007 | Pubmed ID: 17085556
Highly active and selective endopeptidases with programmed substrate specificities.
Nature chemical biology May, 2008 | Pubmed ID: 18391948
An engineered protease that cleaves specifically after sulfated tyrosine.
Angewandte Chemie (International ed. in English) , 2008 | Pubmed ID: 18780393
Construction and flow cytometric screening of targeted enzyme libraries.
Nature protocols , 2009 | Pubmed ID: 19478805
Proteases that can distinguish among different post-translational forms of tyrosine engineered using multicolor flow cytometry.
Journal of the American Chemical Society Dec, 2009 | Pubmed ID: 19924991
A high-throughput single-cell analysis of human CD8⺠T cell functions reveals discordance for cytokine secretion and cytolysis.
The Journal of clinical investigation Nov, 2011 | Pubmed ID: 21965332
Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2012 | Pubmed ID: 22355106
Multi-copy genes that enhance the yield of mammalian G protein-coupled receptors in Escherichia coli.
Metabolic engineering Sep, 2012 | Pubmed ID: 22609824
Single-cell characterization of autotransporter-mediated Escherichia coli surface display of disulfide bond-containing proteins.
The Journal of biological chemistry Nov, 2012 | Pubmed ID: 23019324
High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire.
Nature biotechnology Jan, 2013 | Pubmed ID: 23334449
University of Houston
Ivan Liadi1,
Jason Roszik2,
Gabrielle Romain1,
Laurence J.N. Cooper2,
Navin Varadarajan1
1Department of Chemical and Biomolecular Engineering, University of Houston ,
2Division of Pediatrics, Research Unit 907, University of Texas MD Anderson Cancer Center
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