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Georg-August University

4 ARTICLES PUBLISHED IN JoVE

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Biology

Monitoring Intraspecies Competition in a Bacterial Cell Population by Cocultivation of Fluorescently Labelled Strains
Lorena Stannek 1, Richard Egelkamp 1, Katrin Gunka 1, Fabian M. Commichau 1
1Department of General Microbiology, Georg-August University

Bacteria may accumulate either detrimental or beneficial mutations during their lifetime. In a population of cells individuals that have accumulated beneficial mutations may rapidly outcompete their fellows. Here we present a simple procedure to visualize intraspecies competition in a bacterial cell population over time using fluorescently labeled individuals. 

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Behavior

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
Aidan Dominic Roche 1,2, Ivan Vujaklija 3,4, Sebastian Amsüss 3,4, Agnes Sturma 1,5, Peter Göbel 6, Dario Farina 3,4, Oskar C. Aszmann 1,2
1Christian Doppler Laboratory for Restoration of Extremity Function, 2Department of Surgery, Division of Plastic and Reconstructive Surgery, Medical University of Vienna, 3Department of Neurorehabilitation Engineering, Bernstein Focus Neurotechnology Göttingen, 4University Medical Center Göttingen, Georg-August University, 5University of Applied Sciences FH Campus Wien, 6Research & Development, Otto Bock Healthcare Products GmbH

As prosthetic development moves towards the goal of natural control, harnessing amputees’ inherent ability to learn new motor skills may enable proficiency. This manuscript describes a structured rehabilitation protocol, which includes imitation, repetition, and reinforcement learning strategies, for improved multifunctional prosthetic control.

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Medicine

Structured Motor Rehabilitation After Selective Nerve Transfers
Agnes Sturma 1,2,3, Laura A. Hruby 1,4, Dario Farina 2, Oskar C. Aszmann 1,5
1Clinical Laboratory for Bionic Extremity Reconstruction, Medical University of Vienna, 2Bioengineering Department, Imperial College London, 3Master's Degree Program Health Assisting Engineering, University of Applied Sciences FH Campus Wien, 4Department of Orthopedics and Trauma Surgery, Medical University of Vienna, 5Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna

Here, we present a protocol for the motor rehabilitation of patients with severe nerve injuries and selective nerve transfer surgery. It aims at restoring the motor function proposing several stages in patient education, early-stage therapy after surgery and interventions for rehabilitation after successful re-innervation of the nerve’s target.

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JoVE Core

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers
Agnes Sturma 1,2, Laura A. Hruby 1,3, Anna Boesendorfer 1, Clemens Gstoettner 1, Dario Farina 2, Oskar C. Aszmann 1,4
1Clinical Laboratory for Bionic Extremity Reconstruction, Medical University of Vienna, 2Bioengineering Department, Imperial College London, 3Department of Orthopaedics and Trauma Surgery, Medical University of Vienna, 4Department of Plastic and Reconstructive Surgery, Medical University of Vienna

This work presents a protocol to enhance prosthetic function after selective nerve transfer surgery. Rehabilitation interventions include patient information and selection, support of wound healing, cortical re-activation of sensory-motor areas of the upper limb, training of selective muscle activation, prosthetic handling in daily life, and regular follow-up assessments.

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