Harvard Medical School - BIDMC

1 ARTICLES PUBLISHED IN JoVE

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Immunology and Infection

An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics
Roberta Martinelli 1, Christopher V. Carman 1
1Department of Medicine, Harvard Medical School - BIDMC

Adaptive immunity is controlled by dynamic 'immunological synapses' formed between T cells and antigen presenting cells. This protocol describes methods for investigating endothelial cells both as understudied physiologic APCs and as a novel type of 'planar cellular APC model'.

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