An Endothelial Planar Cell Model for Imaging Immunological Synapse DynamicsRoberta Martinelli 1, Christopher V. Carman 1
1Department of Medicine, Harvard Medical School - BIDMC
Adaptive immunity is controlled by dynamic 'immunological synapses' formed between T cells and antigen presenting cells. This protocol describes methods for investigating endothelial cells both as understudied physiologic APCs and as a novel type of 'planar cellular APC model'.
