Department of Biochemistry and Biophysics
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Oxyphor R2 and G2: phosphors for measuring oxygen by oxygen-dependent quenching of phosphorescence.
Analytical biochemistry Nov, 2002 | Pubmed ID: 12423638
Influence of nonplanarity and extended conjugation on porphyrin basicity.
Inorganic chemistry Dec, 2002 | Pubmed ID: 12495329
Oxygen distributions in tissue measured by phosphorescence quenching.
Advances in experimental medicine and biology , 2003 | Pubmed ID: 12580425
Luminescent Zn and Pd tetranaphthaloporphyrins.
Inorganic chemistry Jul, 2003 | Pubmed ID: 12844293
Novel route to functionalized tetraaryltetra[2,3]naphthaloporphyrins via oxidative aromatization.
The Journal of organic chemistry Sep, 2003 | Pubmed ID: 12968910
Novel versatile synthesis of substituted tetrabenzoporphyrins.
The Journal of organic chemistry Jan, 2004 | Pubmed ID: 14725469
Phosphorescence lifetime imaging in turbid media: the inverse problem and experimental image reconstruction.
Applied optics Jan, 2004 | Pubmed ID: 14765914
Monitoring the dynamics of tissue oxygenation in vivo by phosphorescence quenching.
Advances in experimental medicine and biology , 2003 | Pubmed ID: 15174594
Self-assembly of amphiphilic dendritic dipeptides into helical pores.
Nature Aug, 2004 | Pubmed ID: 15306805
Flexibility in proteins: tuning the sensitivity to O2 diffusion by varying the lifetime of a phosphorescent sensor in horseradish peroxidase.
Photochemistry and photobiology Jul-Aug, 2004 | Pubmed ID: 15339214
Oxygen distribution in murine tumors: characterization using oxygen-dependent quenching of phosphorescence.
Journal of applied physiology (Bethesda, Md. : 1985) Apr, 2005 | Pubmed ID: 15579567
Arylamide dendrimers with flexible linkers via haloacyl halide method.
Organic letters Apr, 2005 | Pubmed ID: 15844900
Synthesis of symmetrical tetraaryltetranaphtho[2,3]porphyrins.
The Journal of organic chemistry Jun, 2005 | Pubmed ID: 15932297
Phosphorescent oxygen sensor with dendritic protection and two-photon absorbing antenna.
Journal of the American Chemical Society Aug, 2005 | Pubmed ID: 16104764
Oxygen distribution and vascular injury in the mouse eye measured by phosphorescence-lifetime imaging.
Applied optics Sep, 2005 | Pubmed ID: 16149347
Synthesis and luminescence of soluble meso-unsubstituted tetrabenzo- and tetranaphtho[2,3]porphyrins.
The Journal of organic chemistry Nov, 2005 | Pubmed ID: 16268634
Imaging oxygen pressure in the retina of the mouse eye.
Advances in experimental medicine and biology , 2005 | Pubmed ID: 16594148
Feasibility of diffuse optical imaging with long-lived luminescent probes.
Optics letters Apr, 2006 | Pubmed ID: 16625910
Oxygen pressures in the interstitial space and their relationship to those in the blood plasma in resting skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985) Dec, 2006 | Pubmed ID: 16888050
Imaging oxygen pressure in the rodent retina by phosphorescence lifetime.
Advances in experimental medicine and biology , 2006 | Pubmed ID: 16927680
Simultaneous fluorometry and phosphorometry of Langendorff perfused rat heart: ex vivo animal studies.
Optics letters Oct, 2006 | Pubmed ID: 17001378
Tomographic imaging of oxygen by phosphorescence lifetime.
Applied optics Nov, 2006 | Pubmed ID: 17086268
Energy and electron transfer in enhanced two-photon-absorbing systems with triplet cores.
The journal of physical chemistry. A Aug, 2007 | Pubmed ID: 17608457
Selective transport of water mediated by porous dendritic dipeptides.
Journal of the American Chemical Society Sep, 2007 | Pubmed ID: 17784763
Oxygen pressures in the interstitial space of skeletal muscle and tumors in vivo.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 18290314
Influence of optical heterogeneities on reconstruction of spatial phosphorescence lifetime distributions.
Optics letters Apr, 2008 | Pubmed ID: 18414531
Synthesis of 5,15-diaryltetrabenzoporphyrins.
The Journal of organic chemistry Jun, 2008 | Pubmed ID: 18452337
Oxygen microscopy by two-photon-excited phosphorescence.
Chemphyschem : a European journal of chemical physics and physical chemistry Aug, 2008 | Pubmed ID: 18663708
Effects of structural deformations on optical properties of tetrabenzoporphyrins: free-bases and Pd complexes.
The journal of physical chemistry. A Aug, 2008 | Pubmed ID: 18665576
Dynamic Quenching of Porphyrin Triplet States by Two-Photon Absorbing Dyes: Towards Two-Photon-Enhanced Oxygen Nanosensors.
Journal of photochemistry and photobiology. A, Chemistry , 2008 | Pubmed ID: 19030124
Precise detection of pH inside large unilamellar vesicles using membrane-impermeable dendritic porphyrin-based nanoprobes.
Analytical biochemistry May, 2009 | Pubmed ID: 19248752
Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression.
Applied optics Apr, 2009 | Pubmed ID: 19340106
Design of Metalloporphyrin-Based Dendritic Nanoprobes for Two-Photon Microscopy of Oxygen.
Journal of porphyrins and phthalocyanines Dec, 2008 | Pubmed ID: 19763243
Optical monitoring of oxygen tension in cortical microvessels with confocal microscopy.
Optics express Dec, 2009 | Pubmed ID: 20052157
Dendritic phosphorescent probes for oxygen imaging in biological systems.
ACS applied materials & interfaces Jun, 2009 | Pubmed ID: 20072726
Neutrophil alpha-defensins cause lung injury by disrupting the capillary-epithelial barrier.
American journal of respiratory and critical care medicine May, 2010 | Pubmed ID: 20093642
Two-photon microscopy of oxygen: polymersomes as probe carrier vehicles.
The journal of physical chemistry. B Nov, 2010 | Pubmed ID: 20462225
Pi-extended dipyrrins capable of highly fluorogenic complexation with metal ions.
Journal of the American Chemical Society Jul, 2010 | Pubmed ID: 20583759
Palmitic acid acutely inhibits acetylcholine- but not GLP-1-stimulated insulin secretion in mouse pancreatic islets.
American journal of physiology. Endocrinology and metabolism Sep, 2010 | Pubmed ID: 20606076
Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue.
Nature methods Sep, 2010 | Pubmed ID: 20693997
Highly non-planar dendritic porphyrin for pH sensing: observation of porphyrin monocation.
Inorganic chemistry Nov, 2010 | Pubmed ID: 20882973
Oxygen-dependent quenching of phosphorescence used to characterize improved myocardial oxygenation resulting from vasculogenic cytokine therapy.
Journal of applied physiology (Bethesda, Md. : 1985) May, 2011 | Pubmed ID: 21292844
Evaluation of phototoxicity of dendritic porphyrin-based phosphorescent oxygen probes: an in vitro study.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology Jun, 2011 | Pubmed ID: 21409208
Measuring oxygen in living tissue: intravascular, interstitial, and "tissue" oxygen measurements.
Advances in experimental medicine and biology , 2011 | Pubmed ID: 21445769
Simultaneous two-photon imaging of oxygen and blood flow in deep cerebral vessels.
Nature medicine Jul, 2011 | Pubmed ID: 21642977
Single cell responses to spatially controlled photosensitized production of extracellular singlet oxygen.
Photochemistry and photobiology Sep-Oct, 2011 | Pubmed ID: 21668871
"Overshoot" of Oâ‚‚ is required to maintain baseline tissue oxygenation at locations distal to blood vessels.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2011 | Pubmed ID: 21940458
Two new "protected" oxyphors for biological oximetry: properties and application in tumor imaging.
Analytical chemistry Nov, 2011 | Pubmed ID: 21961699
Frontiers in optical imaging of cerebral blood flow and metabolism.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Jan, 2012 | Pubmed ID: 22252238
Monitoring Cardiopulmonary Function and Progression Toward Shock: Oxygen Micro-sensor for Peripheral Tissue.
Advances in experimental medicine and biology , 2012 | Pubmed ID: 22259105
Sava Sakadžić1,
Emmanuel Roussakis2,
Mohammad A. Yaseen1,
Emiri T. Mandeville3,
Vivek J. Srinivasan1,
Ken Arai3,
Svetlana Ruvinskaya1,
Weicheng Wu1,
Anna Devor1,4,
Eng H. Lo3,
Sergei A. Vinogradov2,
David A. Boas1
1Optics Division, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School,
2Department of Biochemistry and Biophysics, University of Pennsylvania,
3Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School,
4Departments of Neurosciences and Radiology, University of California
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