Andrew Tsourkas

Structure-function relationships of shared-stem and conventional molecular beacons.

Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets.

Hybridization kinetics and thermodynamics of molecular beacons.

Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets.

Spectroscopic features of dual fluorescence/luminescence resonance energy-transfer molecular beacons.

Dual FRET molecular beacons for mRNA detection in living cells.

Magnetic relaxation switch immunosensors detect enantiomeric impurities.

Shedding light on health and disease using molecular beacons.

Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle.

Detection of peroxidase/H2O2-mediated oxidation with enhanced yellow fluorescent protein.

In vivo imaging of activated endothelium using an anti-VCAM-1 magnetooptical probe.

Superparamagnetic iron oxide nanoparticle probes for molecular imaging.

Engineering nanostructured probes for sensitive intracellular gene detection.

Suicide gene delivery by calcium phosphate nanoparticles: a novel method of targeted therapy for gastric cancer.

Avoiding false-positive signals with nuclease-vulnerable molecular beacons in single living cells.

Iron chelator-based amplification strategy for improved targeting of transferrin receptor with SPIO.

Efficient cytosolic delivery of molecular beacon conjugates and flow cytometric analysis of target RNA.

Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells.

Paramagnetic porous polymersomes.

Assessing the sensitivity of commercially available fluorophores to the intracellular environment.

In vivo imaging of cancer biomarkers using activatable molecular probes.

Fluorescent probes for live-cell RNA detection.

Imaging individual microRNAs in single mammalian cells in situ.

Comparative analysis of nanoparticle-antibody conjugations: carbodiimide versus click chemistry.

Sub-cellular trafficking and functionality of 2'-O-methyl and 2'-O-methyl-phosphorothioate molecular beacons.

Two-photon imaging of multicellular tumor spheroids: a novel method for evaluating the efficacy of CDC25 phosphatase inhibitors.

Gadolinium-conjugated dendrimer nanoclusters as a tumor-targeted T1 magnetic resonance imaging contrast agent.

Imaging circulating cells and lymphoid tissues with iron oxide nanoparticles.

In vivo, multimodal imaging of B cell distribution and response to antibody immunotherapy in mice.

Ratiometric bimolecular beacons for the sensitive detection of RNA in single living cells.

Examination of folate-targeted liposomes with encapsulated poly(2-propylacrylic acid) as a pH-responsive nanoplatform for cytosolic drug delivery.

An intein-mediated site-specific click conjugation strategy for improved tumor targeting of nanoparticle systems.

Quantification of miRNA abundance in single cells using locked nucleic acid-FISH and enzyme-labeled fluorescence.

Delivery of molecular beacons for live-cell imaging and analysis of RNA.

Superparamagnetic iron oxide-enhanced magnetic resonance imaging of neuroinflammation in a rat model of radicular pain.

Firefly luciferase and RLuc8 exhibit differential sensitivity to oxidative stress in apoptotic cells.

Improved tumor targeting of polymer-based nanovesicles using polymer-lipid blends.

pH-titratable superparamagnetic iron oxide for improved nanoparticle accumulation in acidic tumor microenvironments.

ICP-MS analysis of lanthanide-doped nanoparticles as a non-radiative, multiplex approach to quantify biodistribution and blood clearance.

Xanthine oxidase-generated hydrogen peroxide is a consequence, not a mediator of cell death.

Effect of ligand density, receptor density, and nanoparticle size on cell targeting.

Emerging role of radiolabeled nanoparticles as an effective diagnostic technique.

Improving nanoparticle delivery with anti-angiogenesis therapy.

Simultaneous quantification of tumor uptake for targeted and nontargeted liposomes and their encapsulated contents by ICPMS.

Synergizing radiation therapy with drug-loaded nanovectors.

Enhancing the cell uptake of nanoparticles within tumors.

Targeted and drug-loaded micelles.

Biodegradable polydisulfide dendrimer nanoclusters as MRI contrast agents.

Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities.

Porous Polymersomes with Encapsulated Gd-labeled Dendrimers as Highly Efficient MRI Contrast Agents.

Gd-based macromolecules and nanoparticles as magnetic resonance contrast agents for molecular imaging.

Selective targeting of brain tumors with gold nanoparticle-induced radiosensitization.

Quantitative assessment of ratiometric bimolecular beacons as a tool for imaging single engineered RNA transcripts and measuring gene expression in living cells.

Gd-labeled glycol chitosan as a pH-responsive magnetic resonance imaging agent for detecting acidic tumor microenvironments.

Sortase-tag expressed protein ligation: combining protein purification and site-specific bioconjugation into a single step.

Assessment of global cardiac uptake of radiolabeled iron oxide nanoparticles in apolipoprotein-E-deficient mice: implications for imaging cardiovascular inflammation.

Gold-loaded polymeric micelles for computed tomography-guided radiation therapy treatment and radiosensitization.

Imaging the directed transport of single engineered RNA transcripts in real-time using ratiometric bimolecular beacons.

Stabilized porous liposomes with encapsulated Gd-labeled dextran as a highly efficient MRI contrast agent.

Theranostic gold nanoparticles modified for durable systemic circulation effectively and safely enhance the radiation therapy of human sarcoma cells and tumors.

Facile Method for the Site-Specific, Covalent Attachment of Full-Length IgG onto Nanoparticles.

A Novel Chitosan-Hydrogel-Based Nanoparticle Delivery System for Local Inner Ear Application.

Exploring silver as a contrast agent for contrast-enhanced dual-energy x-ray breast imaging.

Quantitative Comparison of Tumor Delivery for Multiple Targeted Nanoparticles Simultaneously by Multiplex ICP-MS.