Wilfred R. Hagen

Hybrid cluster proteins (HCPs) from Desulfovibrio desulfuricans ATCC 27774 and Desulfovibrio vulgaris (Hildenborough): X-ray structures at 1.25 A resolution using synchrotron radiation.

Spectroscopic characterization and ligand-binding properties of chlorite dismutase from the chlorate respiring bacterial strain GR-1.

Deuterium isotope effect on enantioselectivity in the Comamonas testosteroni quinohemoprotein alcohol dehydrogenase-catalyzed kinetic resolution of rac-2,2-dimethyl-4-hydroxymethyl-1,3-dioxolane, solketal.

Characterization of the chlorate reductase from Pseudomonas chloritidismutans.

Two W-containing formate dehydrogenases (CO2-reductases) involved in syntrophic propionate oxidation by Syntrophobacter fumaroxidans.

Reduced hybrid cluster proteins (HCP) from Desulfovibrio desulfuricans ATCC 27774 and Desulfovibrio vulgaris (Hildenborough): X-ray structures at high resolution using synchrotron radiation.

Characterization of the corrinoid iron-sulfur protein tetrachloroethene reductive dehalogenase of Dehalobacter restrictus.

Redox characteristics of the tungsten DMSO reductase of Rhodobacter capsulatus.

Tuning the setup of sputter-coated multilayers in nanocluster-based signal-enhancing biochips for optimal performance in protein and DNA assays.

Purification and characterization of the tungsten enzyme aldehyde:ferredoxin oxidoreductase from the hyperthermophilic denitrifier Pyrobaculum aerophilum.

A three-component dicamba O-demethylase from Pseudomonas maltophilia, strain DI-6: purification and characterization.

EPR analysis of multiple forms of [4Fe-4S](3+) clusters in HiPIPs.

The dinuclear iron-oxo ferroxidase center of Pyrococcus furiosus ferritin is a stable prosthetic group with unexpectedly high reduction potentials.

WOR5, a novel tungsten-containing aldehyde oxidoreductase from Pyrococcus furiosus with a broad substrate Specificity.

A highly thermostable ferritin from the hyperthermophilic archaeal anaerobe Pyrococcus furiosus.

Crystallization and preliminary X-ray characterization of a ferritin from the hyperthermophilic archaeon and anaerobe Pyrococcus furiosus.

Expression, purification, crystallization and preliminary crystallographic analysis of a stand-alone RAM domain with hydrolytic activity from the hyperthermophile Pyrococcus furiosus.

Computational study of ground-state chiral induction in small peptides: comparison of the relative stability of selected amino acid dimers and oligomers in homochiral and heterochiral combinations.

Evidence supporting a cis-enediol-based mechanism for Pyrococcus furiosus phosphoglucose isomerase.

Pyrococcus furiosus 4Fe-ferredoxin, chemisorbed on gold, exhibits gated reduction and ionic strength dependent dimerization.

Redox chemistry of tungsten and iron-sulfur prosthetic groups in Pyrococcus furiosus formaldehyde ferredoxin oxidoreductase.

Tungsten transport protein A (WtpA) in Pyrococcus furiosus: the first member of a new class of tungstate and molybdate transporters.

EPR spectroscopy as a probe of metal centres in biological systems.

EPR studies of recombinant horse L-chain apoferritin and its mutant (E 53,56,57,60 Q) with haemin.

Modeling the 2-His-1-carboxylate facial triad: iron-catecholato complexes as structural and functional models of the extradiol cleaving dioxygenases.

Crystal structure of the ferritin from the hyperthermophilic archaeal anaerobe Pyrococcus furiosus.

Iron(III)-catecholato complexes as structural and functional models of the intradiol-cleaving catechol dioxygenases.

A steady-state and pre-steady-state kinetics study of the tungstoenzyme formaldehyde ferredoxin oxidoreductase from Pyrococcus furiosus.

Function of MoaB proteins in the biosynthesis of the molybdenum and tungsten cofactors.

Reinvestigation of the steady-state kinetics and physiological function of the soluble NiFe-hydrogenase I of Pyrococcus furiosus.

Unprecedented stable aqueous semiquinone methide radical formation interferes with adsorptive cathodic stripping voltammetry of cobalt methyl thymol blue.

Development of a generic approach to native metalloproteomics: application to the quantitative identification of soluble copper proteins in Escherichia coli.

A thermostable hybrid cluster protein from Pyrococcus furiosus: effects of the loss of a three helix bundle subdomain.

Voltammetry of Pyrococcus furiosus ferritin: dependence of iron release rate on mediator potential.

Oleate hydratase catalyzes the hydration of a nonactivated carbon-carbon bond.

Identification of two [4Fe-4S]-cluster-containing hydro-lyases from Pyrococcus furiosus.

Catalysis of iron core formation in Pyrococcus furiosus ferritin.

One- and two-electron reduction of molybdate reversibly bound to the archaeal tungstate/molybdate transporter WtpA.

Development of a bionanotechnological phosphate removal system with thermostable ferritin.

Molybdenum incorporation in tungsten aldehyde oxidoreductase enzymes from Pyrococcus furiosus.

Reversible biological Birch reduction at an extremely low redox potential.

Inhibition and stimulation of formation of the ferroxidase center and the iron core in Pyrococcus furiosus ferritin.

Metallomic EPR spectroscopy.

The tungsten metallome of Pyrococcus furiosus.

A molecular basis for tungstate selectivity in prokaryotic ABC transport systems.

Exploring the microbial metalloproteome using MIRAGE.

A novel mechanism of iron-core formation by Pyrococcus furiosus archaeoferritin, a member of an uncharacterized branch of the ferritin-like superfamily.

A synthetic peptide with the putative iron binding motif of amyloid precursor protein (APP) does not catalytically oxidize iron.

Microbial metalloproteomes explored using MIRAGE.

The catalytic center of ferritin regulates iron storage via Fe(II)-Fe(III) displacement.

De novo design, synthesis and characterisation of MP3, a new catalytic four-helix bundle hemeprotein.

Phosphate accelerates displacement of Fe(III) by Fe(II) in the ferroxidase center of Pyrococcus furiosus ferritin.

Biochemical similarities and differences between the catalytic [4Fe-4S] cluster containing fumarases FumA and FumB from Escherichia coli.

Broadband transmission EPR spectroscopy.

A conserved tyrosine in ferritin is a molecular capacitor.

The amyloid precursor protein (APP) does not have a ferroxidase site in its E2 domain.