Department of Molecular Biology and Genetics,
Department of Neuroscience,
Department of Ophthalmology
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Role of a locus control region in the mutually exclusive expression of human red and green cone pigment genes.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2002 | Pubmed ID: 11773636
The vitelliform macular dystrophy protein defines a new family of chloride channels.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2002 | Pubmed ID: 11904445
Frizzled-3 is required for the development of major fiber tracts in the rostral CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2002 | Pubmed ID: 12351730
A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2003 | Pubmed ID: 12657690
Structure-function analysis of the bestrophin family of anion channels.
The Journal of biological chemistry Oct, 2003 | Pubmed ID: 12907679
Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2003 | Pubmed ID: 14500905
A strabismus susceptibility locus on chromosome 7p.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2003 | Pubmed ID: 14519848
Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling.
Science (New York, N.Y.) Dec, 2003 | Pubmed ID: 14671310
Proximal and distal sequences control UV cone pigment gene expression in transgenic zebrafish.
The Journal of biological chemistry Apr, 2004 | Pubmed ID: 14966125
An outer segment localization signal at the C terminus of the photoreceptor-specific retinol dehydrogenase.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2004 | Pubmed ID: 15028754
Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.
Cell Mar, 2004 | Pubmed ID: 15035989
Frizzled6 controls hair patterning in mice.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15169958
Proteolytic shedding of the extracellular domain of photoreceptor cadherin. Implications for outer segment assembly.
The Journal of biological chemistry Oct, 2004 | Pubmed ID: 15284225
Quantitative analysis of neuronal morphologies in the mouse retina visualized by using a genetically directed reporter.
The Journal of comparative neurology Dec, 2004 | Pubmed ID: 15558785
The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2005 | Pubmed ID: 15634773
The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2005 | Pubmed ID: 15872101
Written in our genes?
Science (New York, N.Y.) Jun, 2005 | Pubmed ID: 15961653
Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2006 | Pubmed ID: 16407530
An evolutionary perspective on the photoreceptor damage response.
American journal of ophthalmology Mar, 2006 | Pubmed ID: 16490507
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2006 | Pubmed ID: 16495441
Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches.
The Journal of general physiology Jun, 2006 | Pubmed ID: 16702355
Effects of L1 retrotransposon insertion on transcript processing, localization and accumulation: lessons from the retinal degeneration 7 mouse and implications for the genomic ecology of L1 elements.
Human molecular genetics Jul, 2006 | Pubmed ID: 16723373
Macular degeneration: recent advances and therapeutic opportunities.
Nature reviews. Neuroscience Nov, 2006 | Pubmed ID: 17033682
Mutational analysis of Norrin-Frizzled4 recognition.
The Journal of biological chemistry Feb, 2007 | Pubmed ID: 17158104
Order from disorder: Self-organization in mammalian hair patterning.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2006 | Pubmed ID: 17172440
Tissue/planar cell polarity in vertebrates: new insights and new questions.
Development (Cambridge, England) Feb, 2007 | Pubmed ID: 17259302
Emergence of novel color vision in mice engineered to express a human cone photopigment.
Science (New York, N.Y.) Mar, 2007 | Pubmed ID: 17379811
Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse.
Investigative ophthalmology & visual science Jun, 2007 | Pubmed ID: 17525215
Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis.
Developmental cell Sep, 2007 | Pubmed ID: 17765677
The optokinetic reflex as a tool for quantitative analyses of nervous system function in mice: application to genetic and drug-induced variation.
PloS one , 2008 | Pubmed ID: 18446207
An essential role for Frizzled5 in neuronal survival in the parafascicular nucleus of the thalamus.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2008 | Pubmed ID: 18509025
The genomic response of the retinal pigment epithelium to light damage and retinal detachment.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2008 | Pubmed ID: 18815272
An essential role for frizzled 5 in mammalian ocular development.
Development (Cambridge, England) Nov, 2008 | Pubmed ID: 18832390
Genetically-directed, cell type-specific sparse labeling for the analysis of neuronal morphology.
PloS one , 2008 | Pubmed ID: 19116659
Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells.
Neuron Mar, 2009 | Pubmed ID: 19323995
The evolution of Primate color vision.
Scientific American Apr, 2009 | Pubmed ID: 19363921
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization.
Cell Oct, 2009 | Pubmed ID: 19837032
New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling.
PloS one , 2009 | Pubmed ID: 19924248
An MRI-based atlas and database of the developing mouse brain.
NeuroImage Jan, 2011 | Pubmed ID: 20656042
The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease.
Trends in molecular medicine Sep, 2010 | Pubmed ID: 20688566
Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling.
Vision research Jan, 2011 | Pubmed ID: 20826176
Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.
Development (Cambridge, England) Nov, 2010 | Pubmed ID: 20940229
Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain.
Gene expression patterns : GEP Jan-Feb, 2011 | Pubmed ID: 21055480
When whorls collide: the development of hair patterns in frizzled 6 mutant mice.
Development (Cambridge, England) Dec, 2010 | Pubmed ID: 21062866
China's plan flawed but courageous.
Science (New York, N.Y.) Dec, 2010 | Pubmed ID: 21163997
Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney.
Development (Cambridge, England) Mar, 2011 | Pubmed ID: 21343368
Preclinical assessment of CNS drug action using eye movements in mice.
The Journal of clinical investigation Sep, 2011 | Pubmed ID: 21821912
Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.
Neuron Aug, 2011 | Pubmed ID: 21835343
Signaling by sensory receptors.
Cold Spring Harbor perspectives in biology Jan, 2012 | Pubmed ID: 22110046
Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2012 | Pubmed ID: 22262898
Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes.
Development (Cambridge, England) Dec, 2012 | Pubmed ID: 23095888
Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity.
Cell Dec, 2012 | Pubmed ID: 23217714
Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling.
eLife , 2012 | Pubmed ID: 23256042
Responses of hair follicle-associated structures to loss of planar cell polarity signaling.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2013 | Pubmed ID: 23431170
How to draw the line in biomedical research.
eLife , 2013 | Pubmed ID: 23538852
Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2013 | Pubmed ID: 24043815
Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons.
eLife , 2013 | Pubmed ID: 24347548
Cellular resolution maps of X chromosome inactivation: implications for neural development, function, and disease.
Neuron Jan, 2014 | Pubmed ID: 24411735
Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system.
Proceedings of the National Academy of Sciences of the United States of America May, 2014 | Pubmed ID: 24799694
Complete morphologies of basal forebrain cholinergic neurons in the mouse.
eLife , 2014 | Pubmed ID: 24894464
1Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine,
2Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine,
3Department of Ophthalmology, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine
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