Center for Applied Proteomics and Molecular Medicine
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Protein microarrays: meeting analytical challenges for clinical applications.
Cancer cell Apr, 2003 | Pubmed ID: 12726858
Protein microarrays: molecular profiling technologies for clinical specimens.
Proteomics Nov, 2003 | Pubmed ID: 14595807
Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2003 | Pubmed ID: 14623978
Molecular diagnostics.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program , 2003 | Pubmed ID: 14633786
Use of proteomic analysis to monitor responses to biological therapies.
Expert opinion on biological therapy Jan, 2004 | Pubmed ID: 14680471
Serum proteomics in cancer diagnosis and management.
Annual review of medicine , 2004 | Pubmed ID: 14746511
Use of proteomic patterns to screen for gastrointestinal malignancies.
Surgery Mar, 2004 | Pubmed ID: 14976472
Clinical proteomics: revolutionizing disease detection and patient tailoring therapy.
Journal of proteome research Mar-Apr, 2004 | Pubmed ID: 15113096
Application of laser capture microdissection and protein microarray technologies in the molecular analysis of airway injury following pollution particle exposure.
Journal of toxicology and environmental health. Part A Jun, 2004 | Pubmed ID: 15205040
Protein microarray detection strategies: focus on direct detection technologies.
Journal of immunological methods Jul, 2004 | Pubmed ID: 15261576
Biomarkers of ovarian tumours.
European journal of cancer (Oxford, England : 1990) Nov, 2004 | Pubmed ID: 15541961
Genomic and proteomic technologies for individualisation and improvement of cancer treatment.
European journal of cancer (Oxford, England : 1990) Nov, 2004 | Pubmed ID: 15541963
Proteomic analysis of human breast cancer tissue with laser-capture microdissection and reverse-phase protein microarrays.
Clinical breast cancer Dec, 2004 | Pubmed ID: 15585078
Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma.
Molecular & cellular proteomics : MCP Apr, 2005 | Pubmed ID: 15671044
Pathology of the future: molecular profiling for targeted therapy.
Cancer investigation , 2005 | Pubmed ID: 15779867
Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment.
The Journal of clinical investigation May, 2005 | Pubmed ID: 15841211
Expression of xeroderma pigmentosum A protein predicts improved outcome in metastatic ovarian carcinoma.
Cancer Jun, 2005 | Pubmed ID: 15844177
Pegylated, steptavidin-conjugated quantum dots are effective detection elements for reverse-phase protein microarrays.
Bioconjugate chemistry May-Jun, 2005 | Pubmed ID: 15898722
Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology May, 2005 | Pubmed ID: 15908672
CSF proteome: a protein repository for potential biomarker identification.
Expert review of proteomics Jan, 2005 | Pubmed ID: 15966853
An interventional magnetic resonance imaging technique for the molecular characterization of intraprostatic dynamic contrast enhancement.
Molecular imaging Jan-Mar, 2005 | Pubmed ID: 15967127
Manual exfoliation of fresh tissue obviates the need for frozen sections for molecular profiling.
Cancer Dec, 2005 | Pubmed ID: 16015639
A transforming growth factor-beta receptor-interacting protein frequently mutated in human ovarian cancer.
Cancer research Aug, 2005 | Pubmed ID: 16061631
Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2005 | Pubmed ID: 16115925
[Development of the protein microarray technique and usefulness in individualized molecular tumor therapy]].
Onkologie Oct, 2005 | Pubmed ID: 16205105
Proteomic analysis of malignant ovarian cancer effusions as a tool for biologic and prognostic profiling.
Clinical cancer research : an official journal of the American Association for Cancer Research Feb, 2006 | Pubmed ID: 16467090
Laser capture microdissection.
Methods in molecular biology (Clifton, N.J.) , 2006 | Pubmed ID: 16719357
Accurate diagnosis of acute graft-versus-host disease using serum proteomic pattern analysis.
Experimental hematology Jun, 2006 | Pubmed ID: 16728285
Physicochemically modified silicon as a substrate for protein microarrays.
Biomaterials Jan, 2007 | Pubmed ID: 16987550
A phase II and pharmacodynamic study of gefitinib in patients with refractory or recurrent epithelial ovarian cancer.
Cancer Apr, 2007 | Pubmed ID: 17330838
Laser-capture microdissection.
Nature protocols , 2006 | Pubmed ID: 17406286
Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival.
Cancer research Apr, 2007 | Pubmed ID: 17409454
The needle in the haystack: application of breast fine-needle aspirate samples to quantitative protein microarray technology.
Cancer Jun, 2007 | Pubmed ID: 17487852
A prospective analysis of imatinib-induced c-KIT modulation in ovarian cancer: a phase II clinical study with proteomic profiling.
Cancer Jul, 2007 | Pubmed ID: 17559139
Development of reverse phase protein microarrays for clinical applications and patient-tailored therapy.
Cancer genomics & proteomics May-Jun, 2007 | Pubmed ID: 17878519
Reverse-phase protein microarrays: application to biomarker discovery and translational medicine.
Expert review of molecular diagnostics Sep, 2007 | Pubmed ID: 17892368
Laser capture microdissection technology.
Expert review of molecular diagnostics Sep, 2007 | Pubmed ID: 17892370
Smart hydrogel particles: biomarker harvesting: one-step affinity purification, size exclusion, and protection against degradation.
Nano letters Jan, 2008 | Pubmed ID: 18076201
Reverse phase protein microarrays for monitoring biological responses.
Methods in molecular biology (Clifton, N.J.) , 2007 | Pubmed ID: 18217695
Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy.
Journal of proteome research Apr, 2008 | Pubmed ID: 18257519
Automated laser capture microdissection for tissue proteomics.
Methods in molecular biology (Clifton, N.J.) , 2008 | Pubmed ID: 18370312
Reverse phase protein microarrays for theranostics and patient-tailored therapy.
Methods in molecular biology (Clifton, N.J.) , 2008 | Pubmed ID: 18370315
Molecular network analysis using reverse phase protein microarrays for patient tailored therapy.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 18593023
A portrait of tissue phosphoprotein stability in the clinical tissue procurement process.
Molecular & cellular proteomics : MCP Oct, 2008 | Pubmed ID: 18667411
Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type.
Molecular & cellular proteomics : MCP Oct, 2008 | Pubmed ID: 18687633
Core-shell hydrogel particles harvest, concentrate and preserve labile low abundance biomarkers.
PloS one , 2009 | Pubmed ID: 19274087
Reverse-phase protein microarrays for theranostics and patient tailored therapy.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19381949
Application of laser microdissection and reverse-phase protein microarrays to the molecular profiling of cancer signal pathway networks in the tissue microenvironment.
Clinics in laboratory medicine Mar, 2009 | Pubmed ID: 19389547
Quantitative cell signalling analysis reveals down-regulation of MAPK pathway activation in colorectal cancer.
The Journal of pathology Aug, 2009 | Pubmed ID: 19396842
Anthrax infection inhibits the AKT signaling involved in the E-cadherin-mediated adhesion of lung epithelial cells.
FEMS immunology and medical microbiology Jul, 2009 | Pubmed ID: 19416348
Activated VEGF receptor shed into the vitreous in eyes with wet AMD: a new class of biomarkers in the vitreous with potential for predicting the treatment timing and monitoring response.
Archives of ophthalmology May, 2009 | Pubmed ID: 19433709
Comparison of global versus epidermal growth factor receptor pathway profiling for prediction of lapatinib sensitivity in bladder cancer.
Neoplasia (New York, N.Y.) Nov, 2009 | Pubmed ID: 19881954
The heme degradation pathway is a promising serum biomarker source for the early detection of Alzheimer's disease.
Journal of Alzheimer's disease : JAD , 2010 | Pubmed ID: 20157261
Nanoparticle technology: amplifying the effective sensitivity of biomarker detection to create a urine test for hGH.
Drug testing and analysis Sep, 2009 | Pubmed ID: 20355230
Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival.
PloS one , 2010 | Pubmed ID: 20421921
Concentration and Preservation of Very Low Abundance Biomarkers in Urine, such as Human Growth Hormone (hGH), by Cibacron Blue F3G-A Loaded Hydrogel Particles.
Nano research Dec, 2008 | Pubmed ID: 20467576
Nanoparticle technology: Addressing the fundamental roadblocks to protein biomarker discovery.
Journal of materials chemistry Aug, 2009 | Pubmed ID: 20585471
Tissue is alive: New technologies are needed to address the problems of protein biomarker pre-analytical variability.
Proteomics. Clinical applications Aug, 2009 | Pubmed ID: 20871745
Tumorigenic and metastatic activity of human thyroid cancer stem cells.
Cancer research Nov, 2010 | Pubmed ID: 20959469
Reverse phase protein microarrays advance to use in clinical trials.
Molecular oncology Dec, 2010 | Pubmed ID: 20974554
The use of hydrogel microparticles to sequester and concentrate bacterial antigens in a urine test for Lyme disease.
Biomaterials Feb, 2011 | Pubmed ID: 21035184
Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL.
PloS one , 2010 | Pubmed ID: 21042412
Reverse-phase phosphoproteome analysis of signaling pathways induced by Rift valley fever virus in human small airway epithelial cells.
PloS one , 2010 | Pubmed ID: 21072193
What is the malignant nature of human ductal carcinoma in situ?
Nature reviews. Cancer Jan, 2011 | Pubmed ID: 21150936
A novel biomarker harvesting nanotechnology identifies Bak as a candidate melanoma biomarker in serum.
Experimental dermatology Jan, 2011 | Pubmed ID: 21158936
Breast cancer stem cells: a new target for therapy.
Oncology (Williston Park, N.Y.) Jan, 2011 | Pubmed ID: 21361239
Reverse phase protein microarrays: fluorometric and colorimetric detection.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21370072
One-step preservation of phosphoproteins and tissue morphology at room temperature for diagnostic and research specimens.
PloS one , 2011 | Pubmed ID: 21858221
Phosphoprotein stability in clinical tissue and its relevance for reverse phase protein microarray technology.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21901591
Multifunctional core-shell nanoparticles: discovery of previously invisible biomarkers.
Journal of the American Chemical Society Nov, 2011 | Pubmed ID: 21999289
Reduction of preanalytical variability in specimen procurement for molecular profiling.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22081338
Laser capture microdissection: Arcturus(XT) infrared capture and UV cutting methods.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22081345
Improved data normalization methods for reverse phase protein microarray analysis of complex biological samples.
BioTechniques Sep, 2012 | Pubmed ID: 22946677
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy Apr, 2012 | Pubmed ID: 22966490
Laser capture microdissection for protein and NanoString RNA analysis.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23027006
Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2012 | Pubmed ID: 23045247
Attacking breast cancer at the preinvasion stage by targeting autophagy.
Women's health (London, England) Mar, 2013 | Pubmed ID: 23477322
Elevated TNFR1 and serotonin in bone metastasis are correlated with poor survival following bone metastasis diagnosis for both carcinoma and sarcoma primary tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2013 | Pubmed ID: 23493346
Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress.
Experimental cell research Aug, 2013 | Pubmed ID: 23669273
Mapping protein signal pathway interaction in sarcoma bone metastasis: linkage between rank, metalloproteinases turnover and growth factor signaling pathways.
Clinical & experimental metastasis Jan, 2014 | Pubmed ID: 23877430
Application of Analyte Harvesting Nanoparticle Technology to the Measurement of Urinary HGH in Healthy Individuals.
Journal of sports medicine & doping studies , 2012 | Pubmed ID: 24014257
Pathologic complete response after preoperative anti-HER2 therapy correlates with alterations in PTEN, FOXO, phosphorylated Stat5, and autophagy protein signaling.
BMC research notes , 2013 | Pubmed ID: 24304724
Glioblastoma cell enrichment is critical for analysis of phosphorylated drug targets and proteomic-genomic correlations.
Cancer research Dec, 2013 | Pubmed ID: 24346432
Ductal carcinoma in situ: challenges, opportunities, and uncharted waters.
American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting , 2012 | Pubmed ID: 24451705
Stratification of clear cell renal cell carcinoma by signaling pathway analysis.
Expert review of proteomics Apr, 2014 | Pubmed ID: 24575852
Protein pathway analysis in Clinical Proteomics using protein microarrays.
Drug discovery today. Technologies , 2005 | Pubmed ID: 24982012
Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces.
Nature communications , 2014 | Pubmed ID: 25048602
Inhibition of Histone Deacetylase 4 Increases Cytotoxicity of Docetaxel in Gastric Cancer Cells.
Proteomics. Clinical applications Aug, 2014 | Pubmed ID: 25091122
Whole proteome analysis of mouse lymph nodes in cutaneous anthrax.
PloS one , 2014 | Pubmed ID: 25329596
Reverse Phase Protein Arrays: Mapping the Path Towards Personalized Medicine.
Molecular diagnosis & therapy Oct, 2014 | Pubmed ID: 25358623
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