Louise Fairall

Telomere architecture.

How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structures.

EM measurements define the dimensions of the "30-nm" chromatin fiber: evidence for a compact, interdigitated structure.

Structural basis for the activation of PPARgamma by oxidized fatty acids.

Negative regulation by nuclear receptors: a plethora of mechanisms.

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

Nuclear hormone receptor co-repressors: structure and function.

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate.

A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death.

Class I HDACs share a common mechanism of regulation by inositol phosphates.

An evolving understanding of nuclear receptor coregulator proteins.

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain.