Krishna P. Kota

Binding of ATP to UAP56 is necessary for mRNA export.

In situ nuclear organization of regulatory machinery.

Development of high-content imaging assays for lethal viral pathogens.

Subnuclear localization and intranuclear trafficking of transcription factors.

Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen.

Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression.

Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery.

Identification of an antioxidant small-molecule with broad-spectrum antiviral activity.

High content image based analysis identifies cell cycle inhibitors as regulators of Ebola virus infection.

Integrating high-content imaging and chemical genetics to probe host cellular pathways critical for yersinia pestis infection.

IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus.

Crimean-Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway.

Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery.

Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns.

Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.

High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses.

High-Content Image-Based Screening of a Signal Transduction Pathway Inhibitor Small-Molecule Library against Highly Pathogenic RNA Viruses.