Centre for Vascular Research
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Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins.
FEBS letters Jan, 2002 | Pubmed ID: 11755528
Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation.
Journal of the American Chemical Society Nov, 2003 | Pubmed ID: 14599211
Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates.
The Biochemical journal Jul, 2004 | Pubmed ID: 15078224
Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation.
The Biochemical journal Oct, 2005 | Pubmed ID: 15932347
Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives.
Journal of the American Chemical Society Mar, 2006 | Pubmed ID: 16506790
Degradation of extracellular matrix and its components by hypobromous acid.
The Biochemical journal Jan, 2007 | Pubmed ID: 17014424
Mammalian heme peroxidases: from molecular mechanisms to health implications.
Antioxidants & redox signaling Jul, 2008 | Pubmed ID: 18331199
Oxidative damage to extracellular matrix and its role in human pathologies.
Free radical biology & medicine Jun, 2008 | Pubmed ID: 18423414
Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides.
The Biochemical journal Jul, 2009 | Pubmed ID: 19379130
Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.
Matrix biology : journal of the International Society for Matrix Biology Jan, 2010 | Pubmed ID: 19788922
Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations.
Biochemical pharmacology Apr, 2010 | Pubmed ID: 19968966
Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains.
Free radical biology & medicine Jul, 2010 | Pubmed ID: 20416372
Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan.
Biochemistry Jul, 2010 | Pubmed ID: 20507176
Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21266577
Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells.
Free radical biology & medicine Dec, 2012 | Pubmed ID: 23059132
Human indoleamine 2,3-dioxygenase is a catalyst of physiological heme peroxidase reactions: implications for the inhibition of dioxygenase activity by hydrogen peroxide.
The Journal of biological chemistry Jan, 2013 | Pubmed ID: 23209301
Mechanism and regulation of peroxidase-catalyzed nitric oxide consumption in physiological fluids: critical protective actions of ascorbate and thiocyanate.
Free radical biology & medicine Jul, 2014 | Pubmed ID: 24704973
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