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Department of Biomedical Physiology and Kinesiology
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Development of a Rab9 transgenic mouse and its ability to increase the lifespan of a murine model of Niemann-Pick type C disease.
The American journal of pathology Jan, 2009 | Pubmed ID: 19056848
Mechanisms and consequences of impaired lipid trafficking in Niemann-Pick type C1-deficient mammalian cells.
Biochimica et biophysica acta Jul, 2009 | Pubmed ID: 19416638
Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice.
The American journal of pathology Dec, 2009 | Pubmed ID: 19893049
Defective cholesterol trafficking in Niemann-Pick C-deficient cells.
FEBS letters Jul, 2010 | Pubmed ID: 20416299
Function of the Niemann-Pick type C proteins and their bypass by cyclodextrin.
Current opinion in lipidology Jun, 2011 | Pubmed ID: 21412152
Niemann-Pick Type C1 deficiency in microglia does not cause neuron death in vitro.
Biochimica et biophysica acta Sep, 2011 | Pubmed ID: 21704157
Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice.
The Journal of biological chemistry Mar, 2012 | Pubmed ID: 22277650
Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis.
PloS one , 2013 | Pubmed ID: 23593276
Simon Fraser University
Kyle Peake1,
John Manning1,
Coral-Ann Lewis1,2,
Christine Barr1,
Fabio Rossi2,
Charles Krieger1,3
1Department of Biomedical Physiology and Kinesiology, Simon Fraser University,
2The Biomedical Research Centre, University of British Columbia,
3Division of Neurology, Department of Medicine, Neuromuscular Disease Unit, VHHSC
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