Cancer Research Program
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Overexpression of glucose-regulated protein 94 (Grp94) in esophageal adenocarcinomas of a rat surgical model and humans.
Carcinogenesis Jan, 2002 | Pubmed ID: 11756233
Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters by tea and curcumin.
Carcinogenesis Aug, 2002 | Pubmed ID: 12151348
Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model.
Carcinogenesis Dec, 2002 | Pubmed ID: 12507933
[Chemopreventive effect of tea and curcumin on DMBA-induced oral carcinogenesis in hamsters].
Wei sheng yan jiu = Journal of hygiene research Oct, 2002 | Pubmed ID: 12572355
Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin.
Journal of the National Cancer Institute Jul, 2003 | Pubmed ID: 12865451
Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.
Carcinogenesis Sep, 2004 | Pubmed ID: 15073046
Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: similarity to human Barrett's esophagus.
Laboratory investigation; a journal of technical methods and pathology Jun, 2004 | Pubmed ID: 15094711
Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2004 | Pubmed ID: 15475461
Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2005 | Pubmed ID: 15756036
Selection of topically applied non-steroidal anti-inflammatory drugs for oral cancer chemoprevention.
Oral oncology Jul, 2005 | Pubmed ID: 15975519
Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors.
Carcinogenesis Sep, 2006 | Pubmed ID: 16632477
Development of an immunocytokine, IL-2-183B2scFv, for targeted immunotherapy of ovarian cancer.
Gynecologic oncology Dec, 2006 | Pubmed ID: 16806435
Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells.
Carcinogenesis Feb, 2007 | Pubmed ID: 16990345
Determination of endogenous tissue inflammation profiles by LC/MS/MS: COX- and LOX-derived bioactive lipids.
Prostaglandins, leukotrienes, and essential fatty acids Dec, 2006 | Pubmed ID: 17011176
Five-lipoxygenase pathway of arachidonic acid metabolism in carcino-genesis and cancer chemoprevention.
Current cancer drug targets Nov, 2006 | Pubmed ID: 17100567
Identification of arsenic-binding proteins in human breast cancer cells.
Cancer letters Sep, 2007 | Pubmed ID: 17499915
Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases.
Oral oncology Jul, 2008 | Pubmed ID: 17936675
Multilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers.
BMC gastroenterology , 2008 | Pubmed ID: 18190713
Depletion of beta-arrestin-2 promotes tumor growth and angiogenesis in a murine model of lung cancer.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2008 | Pubmed ID: 18390755
Zyflamend reduces LTB4 formation and prevents oral carcinogenesis in a 7,12-dimethylbenz[alpha]anthracene (DMBA)-induced hamster cheek pouch model.
Carcinogenesis Nov, 2008 | Pubmed ID: 18687669
Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model.
International journal of cancer. Journal international du cancer Mar, 2009 | Pubmed ID: 19058177
Differential gene expression in normal esophagus and Barrett's esophagus.
Journal of gastroenterology , 2009 | Pubmed ID: 19468668
Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice.
BMC gastroenterology , 2009 | Pubmed ID: 19627616
Stimuli-responsive wettability of nonplanar substrates: pH-controlled floatation and supporting force.
Langmuir : the ACS journal of surfaces and colloids Jan, 2010 | Pubmed ID: 19639980
Zebrafish K5 promoter driven GFP expression as a transgenic system for oral research.
Oral oncology Jan, 2010 | Pubmed ID: 19932050
Chemoprevention of oral cancer in animal models, and effect on leukoplakias in human patients with ZengShengPing, a mixture of medicinal herbs.
Oral oncology Feb, 2010 | Pubmed ID: 20022553
Detecting precancerous lesions in the hamster cheek pouch using spectroscopic white-light optical coherence tomography to assess nuclear morphology via spectral oscillations.
Journal of biomedical optics Nov-Dec, 2009 | Pubmed ID: 20059268
Varying phenotypes in swine versus murine transgenic models constitutively expressing the same human Sonic hedgehog transcriptional activator, K5-HGLI2 Delta N.
Transgenic research Oct, 2010 | Pubmed ID: 20099029
Structural identification of mouse urinary metabolites of pterostilbene using liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM Jun, 2010 | Pubmed ID: 20499322
Tryptase staining of mast cells may differentiate eosinophilic esophagitis from gastroesophageal reflux disease.
The American journal of gastroenterology Feb, 2011 | Pubmed ID: 20978486
Chemopreventive effects of early-stage and late-stage supplementation of vitamin E and selenium on esophageal carcinogenesis in rats maintained on a low vitamin E/selenium diet.
Carcinogenesis Mar, 2011 | Pubmed ID: 21186300
Ethanol promotes chemically induced oral cancer in mice through activation of the 5-lipoxygenase pathway of arachidonic acid metabolism.
Cancer prevention research (Philadelphia, Pa.) Nov, 2011 | Pubmed ID: 21881027
Structural identification of mouse fecal metabolites of theaflavin 3,3'-digallate using liquid chromatography tandem mass spectrometry.
Journal of chromatography. A Oct, 2011 | Pubmed ID: 21906744
Molecular aspects of esophageal development.
Annals of the New York Academy of Sciences Sep, 2011 | Pubmed ID: 21950820
Molecular mechanisms of Barrett's esophagus and adenocarcinoma.
Annals of the New York Academy of Sciences Sep, 2011 | Pubmed ID: 21950830
Molecular mechanisms of Barrett's esophagus.
Digestive diseases and sciences Dec, 2011 | Pubmed ID: 21984436
Time-selective chemoprevention of vitamin E and selenium on esophageal carcinogenesis in rats: the possible role of nuclear factor kappaB signaling pathway.
International journal of cancer. Journal international du cancer Oct, 2012 | Pubmed ID: 22223226
Metabolism of [6]-shogaol in mice and in cancer cells.
Drug metabolism and disposition: the biological fate of chemicals Apr, 2012 | Pubmed ID: 22246389
The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid.
American journal of physiology. Gastrointestinal and liver physiology Apr, 2012 | Pubmed ID: 22301112
Review: Experimental models for Barrett's esophagus and esophageal adenocarcinoma.
American journal of physiology. Gastrointestinal and liver physiology Jun, 2012 | Pubmed ID: 22421618
Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus.
International journal of biochemistry and molecular biology , 2012 | Pubmed ID: 22509480
Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus.
PloS one , 2012 | Pubmed ID: 22567161
Focal endoscopic mucosal resection before radiofrequency ablation is equally effective and safe compared with radiofrequency ablation alone for the eradication of Barrett's esophagus with advanced neoplasia.
Gastrointestinal endoscopy Oct, 2012 | Pubmed ID: 22732872
Diagnostic utility of major basic protein, eotaxin-3, and leukotriene enzyme staining in eosinophilic esophagitis.
The American journal of gastroenterology Oct, 2012 | Pubmed ID: 22777338
6-gingerdiols as the major metabolites of 6-gingerol in cancer cells and in mice and their cytotoxic effects on human cancer cells.
Journal of agricultural and food chemistry Nov, 2012 | Pubmed ID: 23066935
Safety and efficacy of endoscopic mucosal therapy with radiofrequency ablation for patients with neoplastic Barrett's esophagus.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Jun, 2013 | Pubmed ID: 23103824
Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster cheek pouch carcinogenesis by a 5-lipoxygenase inhibitor, garcinol.
Nutrition and cancer , 2012 | Pubmed ID: 23137051
Intestinal metaplasia recurs infrequently in patients successfully treated for Barrett's esophagus with radiofrequency ablation.
The American journal of gastroenterology Feb, 2013 | Pubmed ID: 23247578
Characterization of thiol-conjugated metabolites of ginger components shogaols in mouse and human urine and modulation of the glutathione levels in cancer cells by [6]-shogaol.
Molecular nutrition & food research Mar, 2013 | Pubmed ID: 23322393
Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells.
Cell stem cell Mar, 2013 | Pubmed ID: 23472872
G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis.
Journal of immunology (Baltimore, Md. : 1950) May, 2013 | Pubmed ID: 23589623
Two novel nanoscale preparations of micelle and thermosensitive hydrogel for docetaxel to treat malignant tumor.
Journal of biomedical nanotechnology Mar, 2013 | Pubmed ID: 23620990
Cysteine-conjugated metabolite of ginger component [6]-shogaol serves as a carrier of [6]-shogaol in cancer cells and in mice.
Chemical research in toxicology Jun, 2013 | Pubmed ID: 23638641
Gastroesophageal reflux activates the NF-κB pathway and impairs esophageal barrier function in mice.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2013 | Pubmed ID: 23639809
Synthesis, characterization, and application of amino-terminated poly(ethylene glycol)-block-poly(epsilon-caprolactone) copolymer for paclitaxel.
Journal of nanoscience and nanotechnology Jan, 2013 | Pubmed ID: 23646699
Transgenic overexpression of cdx1b induces metaplastic changes of gene expression in zebrafish esophageal squamous epithelium.
Zebrafish Jun, 2013 | Pubmed ID: 23672288
Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium.
Gut May, 2014 | Pubmed ID: 23676441
Single nucleotide polymorphisms of caudal type homeobox 1 and 2 are associated with Barrett's esophagus.
Digestive diseases and sciences Jan, 2014 | Pubmed ID: 23918153
Cellular origins and molecular mechanisms of Barrett's esophagus and esophageal adenocarcinoma.
Annals of the New York Academy of Sciences Oct, 2013 | Pubmed ID: 24117642
Tissue resistance in the normal and diseased esophagus.
Annals of the New York Academy of Sciences Oct, 2013 | Pubmed ID: 24117643
Identification and pharmacokinetics of novel alkylresorcinol metabolites in human urine, new candidate biomarkers for whole-grain wheat and rye intake.
The Journal of nutrition Feb, 2014 | Pubmed ID: 24259554
Anti-tumor activity and safety evaluation of fisetin-loaded methoxy poly(ethylene glycol)-poly(epsilon-caprolactone) nanoparticles.
Journal of biomedical nanotechnology Apr, 2014 | Pubmed ID: 24734510
NFkB and Nrf2 in esophageal epithelial barrier function.
Tissue barriers Dec, 2013 | Pubmed ID: 24790804
Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Dec, 2014 | Pubmed ID: 24993367
Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo.
Chemical research in toxicology Sep, 2014 | Pubmed ID: 25148906
Pharmacological effects of the water fraction of key components in the traditional Chinese prescription Mai Tong Fang on 3T3-L1 adipocytes and ob/ob diabetic mice.
Molecules (Basel, Switzerland) , 2014 | Pubmed ID: 25230123
Translational research on Barrett's esophagus.
Annals of the New York Academy of Sciences Sep, 2014 | Pubmed ID: 25266024
Surveying mercury levels in hair, blood and urine of under 7-year old children from a coastal city in China.
International journal of environmental research and public health Nov, 2014 | Pubmed ID: 25419876
Molecular mechanisms of ethanol-associated oro-esophageal squamous cell carcinoma.
Cancer letters Jun, 2015 | Pubmed ID: 25766659
Mycoplasma pneumonia combined with pulmonary infarction in a child.
International journal of clinical and experimental medicine , 2015 | Pubmed ID: 25785159
A case of late-onset riboflavin responsive multiple acyl-CoA dehydrogenase deficiency (MADD) with a novel mutation in ETFDH gene.
Journal of the neurological sciences Jun, 2015 | Pubmed ID: 25913573
Quantitative risk stratification of oral leukoplakia with exfoliative cytology.
PloS one , 2015 | Pubmed ID: 25978541
The recyclable synthesis of hierarchical zeolite SAPO-34 with excellent MTO catalytic performance.
Chemical communications (Cambridge, England) Jul, 2015 | Pubmed ID: 26121259
Personalized targeted therapy for esophageal squamous cell carcinoma.
World journal of gastroenterology : WJG Jul, 2015 | Pubmed ID: 26167067
Novel Resveratrol-Based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity.
Journal of medicinal chemistry Aug, 2015 | Pubmed ID: 26204233
1Department of Thoracic Surgery, Ningxia Medical University General Hospital,
2Cancer Research Program, North Carolina Central University,
3Department of Thoracic & Cardiovascular Surgery, The First Affiliated Hospital of Chongqing Medical University,
4Department of Medicine, Center for Esophageal Disease and Swallowing, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill
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