Hans-Achim Wagenknecht

A model nucleoside for electron injection into DNA: 5-pyrenyl-2'-deoxyribose.

Electron injection into DNA: synthesis and spectroscopic properties of pyrenyl-modified oligonucleotides.

Exciton and excimer formation in DNA at room temperature.

Reductive electron transfer and transport of excess electrons in DNA.

Metal-mediated DNA base pairing and metal arrays in artificial DNA: towards new nanodevices.

Pyrene as a fluorescent probe for DNA base radicals.

Synthesis of DNA with phenanthridinium as an artificial DNA base.

Phenanthridinium as an artificial base and charge donor in DNA.

1-Ethynylpyrene as a tunable and versatile molecular beacon for DNA.

Ultrafast proton-coupled electron-transfer dynamics in pyrene-modified pyrimidine nucleosides: model studies towards an understanding of reductive electron transport in DNA.

Detection of single base mismatches and abasic sites using phenanthridinium as an artificial DNA base and charge donor.

Reductive electron transfer in phenothiazine-modified DNA is dependent on the base sequence.

Real-time spectroscopic and chemical probing of reductive electron transfer in DNA.

1-ethynylpyrene-modified guanine and cytosine as optical labels for DNA hybridization.

Electron transfer chemistry between DNA and DNA-binding tripeptides.

Structure-sensitive and self-assembled helical pyrene array based on DNA architecture.

8-(Pyren-1-yl)-2'-deoxyguanosine as an optical probe for DNA hybridization and for charge transfer with small peptides.

DNA as a supramolecular scaffold for the helical arrangement of a stack of 1-ethynylpyrene chromophores.

Base pair motions control the rates and distance dependencies of reductive and oxidative DNA charge transfer.

The search for single DNA damage among millions of base pairs: DNA glycosylases trapped at work.

Perylene-3,4:9,10-tetracarboxylic acid bisimide dye as an artificial DNA base surrogate.

Electron transfer processes in DNA: mechanisms, biological relevance and applications in DNA analytics.

Pyrene-modified guanosine as fluorescent probe for DNA modulated by charge transfer.

DNA labelling topologies for monitoring DNA-protein complex formation by fluorescence anisotropy.

Phenothiazine as a redox-active DNA base substitute: comparison with phenothiazine-modified uridine.

Fluorescent DNA base modifications and substitutes: multiple fluorophore labeling and the DETEQ concept.

Perylene bisimide dimers as fluorescent "glue" for DNA and for base-mismatch detection.

Nucleotide insertion and bypass synthesis of pyrene- and BODIPY-modified oligonucleotides by DNA polymerases.

Thiazole orange and Cy3: improvement of fluorescent DNA probes with use of short range electron transfer.

Fluorescent hydrophobic zippers inside duplex DNA: interstrand stacking of perylene-3,4:9,10-tetracarboxylic acid bisimides as artificial DNA base dyes.

BODIPY-modified uridines as potential fluorescent probes for nucleic acids that are recognized by DNA-polymerases.

Comparison of a nucleosidic vs non-nucleosidic postsynthetic "click" modification of DNA with base-labile fluorescent probes.

Fluorescent color readout of DNA hybridization with thiazole orange as an artificial DNA base.

Helical arrangement of porphyrins along DNA: towards photoactive DNA-based nanoarchitectures.

DNA as a supramolecular framework for the helical arrangements of chromophores: towards photoactive DNA-based nanomaterials.

White-light-emitting DNA (WED).

Photoinduced short-range electron transfer in DNA with fluorescent DNA bases: lessons from ethidium and thiazole orange as charge donors.

Red-white-blue emission switching molecular beacons: ratiometric multicolour DNA hybridization probes.

Imaging of RNA delivery to cells by thiazole orange as a fluorescent RNA base substitution.

Optical, redox, and DNA-binding properties of phenanthridinium chromophores: elucidating the role of the phenyl substituent for fluorescence enhancement of ethidium in the presence of DNA.

In situ azide formation and "click" reaction of nile red with DNA as an alternative postsynthetic route.

Synthesis of spiropyrans as building blocks for molecular switches and dyads.

Synthetic incorporation of Nile Blue into DNA using 2'-deoxyriboside substitutes: Representative comparison of (R)- and (S)-aminopropanediol as an acyclic linker.

New far-red and near-infrared fluorescent probes with large Stokes shifts for dual covalent labeling of DNA.

Non-covalent versus covalent control of self-assembly and chirality of Nile red-modified nucleoside and DNA.

4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene as a bright fluorescent label for DNA.

Assembly of DNA triangles mediated by perylene bisimide caps.

Ratiometric molecular beacons based on the perylene bisimide as a dimeric internal DNA base substitution.

In-stem-labeled molecular beacons for distinct fluorescent color readout.

Polar solvation dynamics in water and methanol: search for molecularity.

5-(Pyren-1-yl)uracil as a base-discriminating fluorescent nucleobase in pyrrolidinyl peptide nucleic acids.

Metal-mediated DNA assembly using the ethynyl linked terpyridine ligand.

A "clickable" styryl dye for fluorescent DNA labeling by excitonic and energy transfer interactions.

"DNA traffic lights": concept of wavelength-shifting DNA probes and application in an aptasensor.

Photoinduced reductive electron transfer in LNA:DNA hybrids: a compromise between conformation and base stacking.

Diarylethene-modified nucleotides for switching optical properties in DNA.

Energy-transfer-based wavelength-shifting DNA probes with "clickable" cyanine dyes.

Synthesis of 4-aminophthalimide and 2,4-diaminopyrimidine C-nucleosides as isosteric fluorescent DNA base substitutes.

RNA "traffic lights": an analytical tool to monitor siRNA integrity.

Synthesis of 2'-O-propargyl nucleoside triphosphates for enzymatic oligonucleotide preparation and "click" modification of DNA with Nile red as fluorescent probe.

Synthesis and redox and photophysical properties of benzodifuran-spiropyran ensembles.

Fluorescence quenching over short range in a donor-DNA-acceptor system.

In-stem labelling allows visualization of DNA strand displacements by distinct fluorescent colour change.

DNA and RNA "traffic lights": synthetic wavelength-shifting fluorescent probes based on nucleic acid base substitutes for molecular imaging.

Development of a metal-ion-mediated base pair for electron transfer in DNA.

Unraveling the pathways to UVA-induced DNA photodamage: (6-4) photoproduct as a potential "Trojan Horse".

DNA-templated formation of fluorescent self-assembly of ethynyl pyrenes.

Conformational control of benzophenone-sensitized charge transfer in dinucleotides.

Synthesis and evaluation of cyanine-styryl dyes with enhanced photostability for fluorescent DNA staining.

Conformational Control of Dual Emission by Pyrrolidinyl PNA-DNA Hybrids.

Photochemically Active Fluorophore-DNA/RNA Conjugates for Cellular Imaging of Nucleic Acids by Readout in Electron Microscopy.

Synthesis of DNA conjugates with metalated tetracationic porphyrins by postsynthetic cycloadditions.

The base discriminating potential of pyrrolidinyl PNA demonstrated by magnetic Fe(x)O(y) particles.

The role of duplex stability for wavelength-shifting fluorescent DNA probes: energy transfer vs. exciton interactions in DNA "traffic lights".

Bifunctional DNA architectonics: three-way junctions with sticky perylene bisimide caps and a central metal lock.

2'-Deoxyuridine conjugated with a reactive monobenzocyclooctyne as a DNA building block for copper-free click-type postsynthetic modification of DNA.

Synthesis and optical properties of pyrrolidinyl peptide nucleic acid carrying a clicked Nile red label.

"Photoclick" postsynthetic modification of DNA.

Mixed non-covalent assemblies of ethynyl nile red and ethynyl pyrene along oligonucleotide templates.

Nucleic acid chemistry.

Acceleration of Long-Range Photoinduced Electron Transfer through DNA by Hydroxyquinolines as Artificial Base Pairs.

Mesityl phenanthroline-modified 2'-deoxyuridine for heteroleptic complexes in metal ion-mediated assembly of DNA.

Development of a wavelength-shifting fluorescent module for the adenosine aptamer using photostable cyanine dyes.

Copper-Free Postsynthetic Labeling of Nucleic Acids by Means of Bioorthogonal Reactions.

DNA-Based Oligochromophores as Light-Harvesting Systems.

Strand displacement and duplex invasion into double-stranded DNA by pyrrolidinyl peptide nucleic acids.

One-Dimensional Multichromophor Arrays Based on DNA: From Self-Assembly to Light-Harvesting.

Dynamic DNA architectures: spontaneous DNA strand exchange and self-sorting driven by perylene bisimide interactions.

A DNA-Fullerene Conjugate as a Template for Supramolecular Chromophore Assemblies: Towards DNA-Based Solar Cells.

Thiazole Orange Dimers in DNA: Fluorescent Base Substitutions with Hybridization Readout.

Polarity Sensitive Bioorthogonally Applicable Far-Red Emitting Labels for Postsynthetic Nucleic Acid Labeling by Copper-Catalyzed and Copper-Free Cycloaddition.

Two wavelength-shifting molecular beacons for simultaneous and selective imaging of vesicular miRNA-21 and miRNA-31 in living cancer cells.