assessing-retinal-microglial-phagocytic-function-vivo-using-flow

Assessing Retinal Microglial Phagocytic Function <em>In Vivo</em> Using a Flow Cytometry-based Assay

Microglia are the tissue resident macrophages of the central nervous system (CNS) and they perform a variety of functions that support CNS homeostasis, ...

The Scripps Research Institute

Several lines of evidence suggest the involvement of antibodies and immune complex inflammation in AMD, a blinding disease with a strong inflammatory component. To examine this further, we developed a novel experimental mouse model of retinal inflammation and evaluated whether inflammation associated with immune complex formation was present in eyes of AMD donors.

Salome Murinello

Department of Cell and Molecular Biology

The Scripps Research Institute

Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay