Department of Biology
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Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2002 | Pubmed ID: 11792860
Maternal infection: window on neuroimmune interactions in fetal brain development and mental illness.
Current opinion in neurobiology Feb, 2002 | Pubmed ID: 11861174
Prenatal viral infection leads to pyramidal cell atrophy and macrocephaly in adulthood: implications for genesis of autism and schizophrenia.
Cellular and molecular neurobiology Feb, 2002 | Pubmed ID: 12064515
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2002 | Pubmed ID: 12151548
Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2003 | Pubmed ID: 12514227
Developmental cooperation of leukemia inhibitory factor and insulin-like growth factor I in mice is tissue-specific and essential for lung maturation involving the transcription factors Sp3 and TTF-1.
Mechanisms of development Mar, 2003 | Pubmed ID: 12591604
Lymphocyte regulation of neuropeptide gene expression after neuronal injury.
Journal of neuroscience research Oct, 2003 | Pubmed ID: 14515353
Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats.
Neuroscience research Mar, 2004 | Pubmed ID: 15154680
Antibodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms.
Methods in molecular biology (Clifton, N.J.) , 2004 | Pubmed ID: 15201451
Potent pro-inflammatory actions of leukemia inhibitory factor in the spinal cord of the adult mouse.
Experimental neurology Aug, 2004 | Pubmed ID: 15246839
Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2004 | Pubmed ID: 15371500
Targeted overexpression of leukemia inhibitory factor to preserve myocardium in a rat model of postinfarction heart failure.
The Journal of thoracic and cardiovascular surgery Dec, 2004 | Pubmed ID: 15573071
Endothelin receptor B inhibition triggers apoptosis and enhances angiogenesis in melanomas.
Cancer research Dec, 2004 | Pubmed ID: 15604257
Maternal influenza infection is likely to alter fetal brain development indirectly: the virus is not detected in the fetus.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience Apr-May, 2005 | Pubmed ID: 15749254
Leukemia inhibitory factor promotes oligodendrocyte survival after spinal cord injury.
Glia Jul, 2005 | Pubmed ID: 15779090
The cell cycle-apoptosis connection revisited in the adult brain.
The Journal of cell biology Nov, 2005 | Pubmed ID: 16291699
Leukemia inhibitory factor is a key regulator of astrocytic, microglial and neuronal responses in a low-dose pilocarpine injury model.
Brain research Feb, 2006 | Pubmed ID: 16458863
Autism: neuropathology, alterations of the GABAergic system, and animal models.
International review of neurobiology , 2005 | Pubmed ID: 16512344
Behavioral stress and tumor progression.
Anticancer research Mar-Apr, 2006 | Pubmed ID: 16619523
Leukemia inhibitory factor promotes neural stem cell self-renewal in the adult brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2006 | Pubmed ID: 17108182
The neuropoietic cytokine family in development, plasticity, disease and injury.
Nature reviews. Neuroscience Mar, 2007 | Pubmed ID: 17311007
A chronically implantable, hybrid cannula-electrode device for assessing the effects of molecules on electrophysiological signals in freely behaving animals.
Journal of neuroscience methods Jul, 2007 | Pubmed ID: 17499854
Molecular basis for passive immunotherapy of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17895381
Maternal immune activation alters fetal brain development through interleukin-6.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2007 | Pubmed ID: 17913903
Neuroscience. Maternal effects on schizophrenia risk.
Science (New York, N.Y.) Oct, 2007 | Pubmed ID: 17962542
Activation of the maternal immune system alters cerebellar development in the offspring.
Brain, behavior, and immunity Jan, 2009 | Pubmed ID: 18755264
Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2008 | Pubmed ID: 18768695
Endothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor.
BMC cancer , 2008 | Pubmed ID: 19040731
Immune involvement in schizophrenia and autism: etiology, pathology and animal models.
Behavioural brain research Dec, 2009 | Pubmed ID: 19136031
IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin.
PloS one , 2009 | Pubmed ID: 19488402
Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment.
The Journal of biological chemistry Aug, 2009 | Pubmed ID: 19491400
Cytokines and CNS development.
Neuron Oct, 2009 | Pubmed ID: 19840550
Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2009 | Pubmed ID: 19864571
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.
The Journal of cell biology Dec, 2009 | Pubmed ID: 20026656
Maternal immune activation alters nonspatial information processing in the hippocampus of the adult offspring.
Brain, behavior, and immunity Aug, 2010 | Pubmed ID: 20227486
Pulsed UV light inactivation of Salmonella enteritidis on eggshells and its effects on egg quality.
Journal of food protection Aug, 2010 | Pubmed ID: 20819349
Antibody therapy in neurodegenerative disease.
Reviews in the neurosciences , 2010 | Pubmed ID: 21086760
Maternal infection and schizophrenia: implications for prevention.
Schizophrenia bulletin Mar, 2011 | Pubmed ID: 21134972
Activation of the maternal immune system induces endocrine changes in the placenta via IL-6.
Brain, behavior, and immunity May, 2011 | Pubmed ID: 21195166
Modeling autistic features in animals.
Pediatric research May, 2011 | Pubmed ID: 21289542
Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1.
PloS one , 2011 | Pubmed ID: 21304966
Maternal infection and immune involvement in autism.
Trends in molecular medicine Jul, 2011 | Pubmed ID: 21482187
Gene therapy in mouse models of huntington disease.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry Apr, 2011 | Pubmed ID: 21489966
The role of IκB kinase complex in the neurobiology of Huntington's disease.
Neurobiology of disease Aug, 2011 | Pubmed ID: 21554955
Maternal infection and autism.
Brain, behavior, and immunity Oct, 2011 | Pubmed ID: 22001185
Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2011 | Pubmed ID: 22072671
Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism.
Brain, behavior, and immunity Jan, 2012 | Pubmed ID: 22310922
Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2012 | Pubmed ID: 22323722
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