Annarita Miccio

Phosphorylation of synapsin I by cAMP-dependent protein kinase controls synaptic vesicle dynamics in developing neurons.

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.

Hot spots of retroviral integration in human CD34+ hematopoietic cells.

The homeodomain transcription factor Prep1 (pKnox1) is required for hematopoietic stem and progenitor cell activity.

In vivo selection of genetically modified erythroblastic progenitors leads to long-term correction of beta-thalassemia.

Transcription factor binding sites are genetic determinants of retroviral integration in the human genome.

NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development.

FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment.

Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes.

The GATA1-HS2 enhancer allows persistent and position-independent expression of a β-globin transgene.

Lentiviral vector integration in the human genome induces alternative splicing and generates aberrant transcripts.

Deletion of the LTR enhancer/promoter has no impact on the integration profile of MLV vectors in human hematopoietic progenitors.

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

Genome-Wide Definition of Promoter and Enhancer Usage during Neural Induction of Human Embryonic Stem Cells.

Dynamic Transcriptional and Epigenetic Regulation of Human Epidermal Keratinocyte Differentiation.

Transcriptional, epigenetic and retroviral signatures identify regulatory regions involved in hematopoietic lineage commitment.

Gene Therapy for β-Hemoglobinopathies.