Institute of Pharmaceutical Science
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Understanding the Physiology of the Blood-Brain Barrier: In Vitro Models.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Dec, 1998 | Pubmed ID: 11390805
Drug resistance in epilepsy: the role of the blood-brain barrier.
Novartis Foundation symposium , 2002 | Pubmed ID: 11990780
Ionic currents in isolated and in situ squid Schwann cells.
The Journal of physiology Jun, 2002 | Pubmed ID: 12068039
Astrocyte-endothelial interactions and blood-brain barrier permeability.
Journal of anatomy Jun, 2002 | Pubmed ID: 12162730
Evaluation of the RBE4 cell line to explore carrier-mediated drug delivery to the CNS via the L-system amino acid transporter at the blood-brain barrier.
Journal of drug targeting Jun, 2002 | Pubmed ID: 12164376
Bradykinin increases permeability by calcium and 5-lipoxygenase in the ECV304/C6 cell culture model of the blood-brain barrier.
Brain research Oct, 2002 | Pubmed ID: 12384249
Interaction between flavonoids and the blood-brain barrier: in vitro studies.
Journal of neurochemistry Apr, 2003 | Pubmed ID: 12641740
Vascular and parenchymal mechanisms in multiple drug resistance: a lesson from human epilepsy.
Current drug targets May, 2003 | Pubmed ID: 12699350
Lipids in blood-brain barrier models in vitro I: Thin-layer chromatography and high-performance liquid chromatography for the analysis of lipid classes and long-chain polyunsaturated fatty acids.
In vitro cellular & developmental biology. Animal Nov-Dec, 2002 | Pubmed ID: 12762837
Lipids in blood-brain barrier models in vitro II: Influence of glial cells on lipid classes and lipid fatty acids.
In vitro cellular & developmental biology. Animal Nov-Dec, 2002 | Pubmed ID: 12762838
Functional characterisation of nucleoside transport in rat brain endothelial cells.
Neuroreport May, 2003 | Pubmed ID: 12802208
An overview of in vitro techniques for blood-brain barrier studies.
Methods in molecular medicine , 2003 | Pubmed ID: 12958429
In vitro trans-monolayer permeability calculations: often forgotten assumptions.
Drug discovery today Nov, 2003 | Pubmed ID: 14643163
Flavonoid permeability across an in situ model of the blood-brain barrier.
Free radical biology & medicine Mar, 2004 | Pubmed ID: 14980703
Cross reactivity of polyclonal GFAP antiserum: implications for the in-vitro characterisation of brain endothelium.
Brain research Jun, 2004 | Pubmed ID: 15158176
Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology.
Neurochemistry international Sep, 2004 | Pubmed ID: 15186921
Brain to blood efflux transport of adenosine: blood-brain barrier studies in the rat.
Journal of neurochemistry Jul, 2004 | Pubmed ID: 15228584
Blood-brain barrier opened by stimulation of the parasympathetic sphenopalatine ganglion: a new method for macromolecule delivery to the brain.
Journal of neurosurgery Aug, 2004 | Pubmed ID: 15309923
Interaction of nucleoside analogues with nucleoside transporters in rat brain endothelial cells.
Journal of drug targeting Jun, 2004 | Pubmed ID: 15512777
Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture.
Journal of neurochemistry May, 2005 | Pubmed ID: 15857386
Dynamics of CNS barriers: evolution, differentiation, and modulation.
Cellular and molecular neurobiology Feb, 2005 | Pubmed ID: 15962506
Astrocyte-endothelial interactions at the blood-brain barrier.
Nature reviews. Neuroscience Jan, 2006 | Pubmed ID: 16371949
P-Glycoprotein expression in human retinal pigment epithelium cell lines.
Experimental eye research Jul, 2006 | Pubmed ID: 16530756
Strategies to advance translational research into brain barriers.
The Lancet. Neurology Jan, 2008 | Pubmed ID: 18093565
All vertebrates started out with a glial blood-brain barrier 4-500 million years ago.
Glia May, 2008 | Pubmed ID: 18338790
Structure and function of the blood-brain barrier.
Neurobiology of disease Jan, 2010 | Pubmed ID: 19664713
An improved in vitro blood-brain barrier model: rat brain endothelial cells co-cultured with astrocytes.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22144323
Establishment of a simplified in vitro porcine blood-brain barrier model with high transendothelial electrical resistance.
Brain research Jul, 2013 | Pubmed ID: 22789905
Delivery of paclitaxel across cellular barriers using a dendrimer-based nanocarrier.
International journal of pharmaceutics Jan, 2013 | Pubmed ID: 23089576
Overview and introduction: the blood-brain barrier in health and disease.
Epilepsia Nov, 2012 | Pubmed ID: 23134489
A detailed method for preparation of a functional and flexible blood-brain barrier model using porcine brain endothelial cells.
Brain research Jul, 2013 | Pubmed ID: 23603406
Blood-brain barrier structure and function and the challenges for CNS drug delivery.
Journal of inherited metabolic disease May, 2013 | Pubmed ID: 23609350
A multi-system approach assessing the interaction of anticonvulsants with P-gp.
PloS one , 2013 | Pubmed ID: 23741405
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
PloS one , 2013 | Pubmed ID: 24204733
Prediction of blood-brain barrier permeation in drug discovery from in vivo, in vitro and in silico models.
Drug discovery today. Technologies Dec, 2004 | Pubmed ID: 24981621
In vitro porcine blood-brain barrier model for permeability studies: pCEL-X software pKa(FLUX) method for aqueous boundary layer correction and detailed data analysis.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Dec, 2014 | Pubmed ID: 25239510
Primary porcine brain microvessel endothelial cell isolation and culture.
Current protocols in neuroscience Oct, 2014 | Pubmed ID: 25297692
Characterization of a novel brain barrier ex vivo insect-based P-glycoprotein screening model.
Pharmacology research & perspectives Aug, 2014 | Pubmed ID: 25505597
The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo.
Biomaterials Jun, 2015 | Pubmed ID: 25890741
LRP-1-mediated intracellular antibody delivery to the Central Nervous System.
Scientific reports Jul, 2015 | Pubmed ID: 26189707
Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo.
Journal of controlled release : official journal of the Controlled Release Society Mar, 2016 | Pubmed ID: 26809004
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism May, 2016 | Pubmed ID: 26868179
Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Jul, 2017 | Pubmed ID: 28337939
Impact of capillary flow hydrodynamics on carrier-mediated transport of opioid derivatives at the blood-brain barrier, based on pH-dependent Michaelis-Menten and Crone-Renkin analyses.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Aug, 2017 | Pubmed ID: 28614733
Uptake and metabolism of sulphated steroids by the blood-brain barrier in the adult male rat.
Journal of neurochemistry Sep, 2017 | Pubmed ID: 28665486
The blood-brain barrier in psychosis.
The lancet. Psychiatry Aug, 2017 | Pubmed ID: 28781208
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