Sharon C-A. Chen

Cryptococcosis in Australasia and the treatment of cryptococcal and other fungal infections with liposomal amphotericin B.

Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans.

A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays.

Cryptococcal phospholipases: a novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii.

Cryptococcal phospholipase B antigen is not detected in serum of patients infected with Cryptococcus neoformans using a sandwich enzyme-linked immunosorbent assay.

In vitro activities of miltefosine and two novel antifungal biscationic salts against a panel of 77 dermatophytes.

Antifungal agents.

Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients.

Molecular typing of Australian Scedosporium isolates showing genetic variability and numerous S. aurantiacum.

Practical method for detection and identification of Candida, Aspergillus, and Scedosporium spp. by use of rolling-circle amplification.

Genotyping of Scedosporium species: a review of molecular approaches.

Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients.

Assignment of Reference 5'-end 16S rDNA Sequences and Species-Specific Sequence Polymorphisms Improves Species Identification of Nocardia.

Identification of pathogenic Nocardia species by reverse line blot hybridization targeting the 16S rRNA and 16S-23S rRNA gene spacer regions.

Comparison of whole blood, serum, and plasma for early detection of candidemia by multiplex-tandem PCR.

Fungal-derived immune modulating molecules.

Protein-losing enteropathy and hypogammaglobulinaemia as first manifestations of disseminated histoplasmosis coincident with Nocardia infection.

In vitro antifungal activities of bis(alkylpyridinium)alkane compounds against pathogenic yeasts and molds.

Antifungal therapy in invasive fungal infections.

secA1 gene sequence polymorphisms for species identification of Nocardia species and recognition of intraspecies genetic diversity.

New molecular and surrogate biomarker-based tests in the diagnosis of bacterial and fungal infection in febrile neutropenic patients.

Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors?

Scedosporium aurantiacum is as virulent as S. prolificans, and shows strain-specific virulence differences, in a mouse model.

Abundance of Pseudallescheria/Scedosporium species in the Australian urban environment suggests a possible source for scedosporiosis including the colonization of airways in cystic fibrosis.

Recent advances in management of cryptococcal meningitis: commentary.

Echinocandin antifungal drugs in fungal infections: a comparison.

Development and validation of a multiplex PCR for detection of Scedosporium spp. in respiratory tract specimens from patients with cystic fibrosis.

Fatal mycotic aneurysms due to Scedosporium and Pseudallescheria infection.

Defining reference sequences for Nocardia species by similarity and clustering analyses of 16S rRNA gene sequence data.

Direct effects of non-antifungal agents used in cancer chemotherapy and organ transplantation on the development and virulence of Candida and Aspergillus species.

Identification of bacteria in blood culture broths using matrix-assisted laser desorption-ionization Sepsityper™ and time of flight mass spectrometry.

Three-locus identification, genotyping, and antifungal susceptibilities of medically important Trichosporon species from China.

Matrix-assisted laser desorption ionization-time of flight mass spectrometry identification of yeasts is contingent on robust reference spectra.

Nosocomial Pneumocystis jirovecii pneumonia: lessons from a cluster in kidney transplant recipients.

Seeking clarity within cloudy effluents: differentiating fungal from bacterial peritonitis in peritoneal dialysis patients.

Pneumonia and lung infections due to emerging and unusual fungal pathogens.

Sporotrichosis (Sporothrix schenckii infection) in the New South Wales mid-north coast, 2000-2010.

Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring.

Multicenter study of posaconazole therapeutic drug monitoring: exposure-response relationship and factors affecting concentration.

In vitro susceptibilities of yeast species to fluconazole and voriconazole as determined by the 2010 National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) study.

Clinical utility of the cryptococcal antigen lateral flow assay in a diagnostic mycology laboratory.

Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory.

Post-transplant Pneumocystis jirovecii pneumonia-a re-emerged public health problem?

Rapid identification of Gram-negative organisms from blood culture bottles using a modified extraction method and MALDI-TOF mass spectrometry.

Fungal infections and treatment in cystic fibrosis.

A loop-mediated isothermal amplification (LAMP) assay for Strongyloides stercoralis in stool that uses a visual detection method with SYTO-82 fluorescent dye.

Thermomyces lanuginosus infective endocarditis: Case report and a review of endocarditis due to uncommon moulds.

Echinocandins in the treatment of candidaemia and invasive candidiasis: clinical and economic perspectives.

Candida quercitrusa candidemia: investigation of three clustered cases and mycological characteristics of this novel species.

Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects.

Clinical utility of Aspergillus galactomannan and PCR in bronchoalveolar lavage fluid for the diagnosis of invasive pulmonary aspergillosis in patients with haematological malignancies.

Clinical utility of caspofungin eye drops in fungal keratitis.

Improved identification of rapidly growing mycobacteria by a 16S-23S internal transcribed spacer region PCR and capillary gel electrophoresis.

Detection of multiple fungal species in blood samples by real-time PCR: an interpretative challenge.

Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype.

Rapid and accurate direct antibiotic susceptibility testing of blood culture broths using MALDI Sepsityper combined with the BD Phoenix automated system.

Cryptococcus gattii infections.

Antifungal susceptibilities of Candida glabrata species complex, Candida krusei, Candida parapsilosis species complex and Candida tropicalis causing invasive candidiasis in China: 3 year national surveillance.

A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.

Rapid microscopy and use of vital dyes: potential to determine viability of Cryptococcus neoformans in the clinical laboratory.

Candida colonization as a risk marker for invasive candidiasis in mixed medical-surgical intensive care units: development and evaluation of a simple, standard protocol.

Invasive infections due to filamentous fungi other than Aspergillus: epidemiology and determinants of mortality.

Contemporary molecular approaches in the clinical microbiology laboratory: progress and pitfalls.

Colonisation with Pneumocystis jirovecii in Australian infants.

Evaluation of point-of-care testing in critically unwell patients: comparison with clinical laboratory analysers and applicability to patients with Ebolavirus infection.

Editorial: Laboratory preparedness for Ebolavirus disease.

What assay is optimal for the diagnosis of measles virus infection? An evaluation of the performance of a measles virus real-time reverse transcriptase PCR using the Cepheid SmartCycler(®) and antigen detection by immunofluorescence.

Antibiotic susceptibility of diverse Mycobacterium abscessus complex strains in New South Wales, Australia.

Accurate Identification of Common Pathogenic Nocardia Species: Evaluation of a Multilocus Sequence Analysis Platform and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.

Chaetomium atrobrunneum and Aspergillus fumigatus in multiple tracheal aspirates: Copathogens or symbiosis.

Concordance of four commercial enzyme immunoassay and three immunoblot formats for the detection of Lyme borreliosis antibodies in human serum: the two-tier approach remains.

Sequencer-Based Capillary Gel Electrophoresis (SCGE) Targeting the rDNA Internal Transcribed Spacer (ITS) Regions for Accurate Identification of Clinically Important Yeast Species.

Performance of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Aspergillus, Scedosporium, and Fusarium spp. in the Australian Clinical Setting.

Successful treatment of Cryptococcus neoformans immune reconstitution inflammatory syndrome in an immunocompetent host using thalidomide.

Safety, clinical effectiveness and trough plasma concentrations of intravenous posaconazole in patients with haematological malignancies and/or undergoing allogeneic haematopoietic stem cell transplantation: off-trial experience.

Identification and Antifungal Susceptibility Profiles of Candida haemulonii Species Complex Clinical Isolates from a Multicenter Study in China.

Antifungal susceptibilities of non-Aspergillus filamentous fungi causing invasive infection in Australia: support for current antifungal guideline recommendations.

Mycological testing of clinical samples in Australasian pathology laboratories: wide diversity and room for improvement.

Problematic Dichotomization of Risk for Intensive Care Unit (ICU)-Acquired Invasive Candidiasis: Results Using a Risk-Predictive Model to Categorize 3 Levels of Risk From a Multicenter Prospective Cohort of Australian ICU Patients.

16S-23S Internal Transcribed Spacer Region PCR and Sequencer-Based Capillary Gel Electrophoresis has Potential as an Alternative to High Performance Liquid Chromatography for Identification of Slowly Growing Nontuberculous Mycobacteria.

Verruconis gallopava cardiac and endovascular infection with dissemination after renal transplantation: Case report and lessons learned.

Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response.

Identification and Antifungal Susceptibility Profiles of Candida nivariensis and Candida bracarensis in a Multi-Center Chinese Collection of Yeasts.

New developments and directions in the clinical application of the echinocandins.

Laboratory Approach to the Diagnosis of Culture-Negative Infective Endocarditis.

Pseudomonas aeruginosa Inhibits the Growth of Scedosporium and Lomentospora In Vitro.

Molecular Epidemiology and Antifungal Susceptibility of Candida glabrata in China (August 2009 to July 2014): A Multi-Center Study.

Challenges in Laboratory Detection of Fungal Pathogens in the Airways of Cystic Fibrosis Patients.

Locally Acquired mcr-1 in Escherichia coli, Australia, 2011 and 2013.

Genome sequencing links persistent outbreak of legionellosis in Sydney to an emerging clone of Legionella pneumophila ST211.