an-vivo-blood-brain-barrier-permeability-assay-mice-using

An <em>In Vivo</em> Blood-brain Barrier Permeability Assay in Mice Using Fluorescently Labeled Tracers

Blood-brain barrier (BBB) is a specialized barrier that protects the brain microenvironment from toxins and pathogens in the circulation and maintains ...

Goethe University Hospital

Neovascularization is a major cause of blindness in various ocular diseases. Bioactive sphingosine 1-phosphate (S1P), synthesized by two sphingosine kinases (Sphk1, Sphk2), emerged as a key player in a multitude of cellular processes, including cell survival, proliferation, inflammation, migration, and angiogenesis. We investigated the role of Sphk2, S1P, and S1P receptors (S1PR) during retinal neovascularization using the oxygen-induced retinopathy mouse model (OIR).

Kavi Devraj

Institute of Neurology (Edinger Institute),
Pharmazentrum Frankfurt,
Institute for General Pharmacology and Toxicology,
Pharmazentrum Frankfurt, Institute for General Pharmacology and Toxicology

Goethe University Hospital

An In Vivo Blood-brain Barrier Permeability Assay in Mice Using Fluorescently Labeled Tracers

Kavi Devraj

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Institute of Neurology (Edinger Institute),Pharmazentrum Frankfurt,Institute for General Pharmacology and Toxicology,Pharmazentrum Frankfurt, Institute for General Pharmacology and Toxicology

Goethe University Hospital

An In Vivo Blood-brain Barrier Permeability Assay in Mice Using Fluorescently Labeled Tracers

Institute of Neurology (Edinger Institute),
Pharmazentrum Frankfurt,
Institute for General Pharmacology and Toxicology,
Pharmazentrum Frankfurt, Institute for General Pharmacology and Toxicology