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Center for Mitochondrial and Epigenomic Medicine
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Transcription errors induce proteotoxic stress and shorten cellular lifespan.
Nature communications Aug, 2015 | Pubmed ID: 26304740
Linking mitochondrial dynamics to mitochondrial protein quality control.
Current opinion in genetics & development 06, 2016 | Pubmed ID: 27235806
The landscape of transcription errors in eukaryotic cells.
Science advances Oct, 2017 | Pubmed ID: 29062891
Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans.
Cell reports Mar, 2018 | Pubmed ID: 29562168
Somatic mutations in neurons during aging and neurodegeneration.
Acta neuropathologica Jun, 2018 | Pubmed ID: 29705908
Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy.
Cell metabolism Aug, 2018 | Pubmed ID: 30174309
Children's Hospital of Philadelphia
Clark Fritsch1,2,
Jean-Francois Pierre Gout3,4,
Marc Vermulst1
1Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia,
2Department of Cellular and Molecular Biology, University of Pennsylvania,
3Department of Biological Sciences, Mississippi State University,
4Center for Mechanisms of Evolution, Biodesign Institute, Arizona State University
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