Center for Cell and Gene Therapy
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Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications.
Blood Feb, 2004 | Pubmed ID: 14525768
Conserved CTL epitopes on the adenovirus hexon protein expand subgroup cross-reactive and subgroup-specific CD8+ T cells.
Blood Oct, 2004 | Pubmed ID: 15265797
Adenovirus as an emerging pathogen in immunocompromised patients.
British journal of haematology Jan, 2005 | Pubmed ID: 15638847
Characterization of latent membrane protein 2 specificity in CTL lines from patients with EBV-positive nasopharyngeal carcinoma and lymphoma.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2005 | Pubmed ID: 16148164
Adenoviral infections in hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Mar, 2006 | Pubmed ID: 16503493
Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.
Nature medicine Oct, 2006 | Pubmed ID: 16998485
Improving T cell therapy for cancer.
Annual review of immunology , 2007 | Pubmed ID: 17129181
Autologous designer antigen-presenting cells by gene modification of T lymphocyte blasts with IL-7 and IL-12.
Journal of immunotherapy (Hagerstown, Md. : 1997) Jul-Aug, 2007 | Pubmed ID: 17589291
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer.
Blood Oct, 2007 | Pubmed ID: 17609424
Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy.
Journal of virology Jan, 2008 | Pubmed ID: 17942545
Using dendritic cell maturation and IL-12 producing capacity as markers of function: a cautionary tale.
Journal of immunotherapy (Hagerstown, Md. : 1997) May, 2008 | Pubmed ID: 18391760
Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy.
Journal of immunotherapy (Hagerstown, Md. : 1997) Sep, 2008 | Pubmed ID: 18600178
Cytotoxic T lymphocytes as immune-therapy in haematological practice.
British journal of haematology Oct, 2008 | Pubmed ID: 18691164
Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2009 | Pubmed ID: 19259067
Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes.
Blood Aug, 2009 | Pubmed ID: 19443656
Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes.
Journal of immunotherapy (Hagerstown, Md. : 1997) Sep, 2009 | Pubmed ID: 19561536
Nucleofection of DCs to generate Multivirus-specific T cells for prevention or treatment of viral infections in the immunocompromised host.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2009 | Pubmed ID: 19584818
Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation.
Blood Nov, 2009 | Pubmed ID: 19700662
Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation.
Blood Apr, 2010 | Pubmed ID: 20110422
Challenges of T cell therapies for virus-associated diseases after hematopoietic stem cell transplantation.
Expert opinion on biological therapy Mar, 2010 | Pubmed ID: 20132056
Antigen-specific cytotoxic T lymphocytes can target chemoresistant side-population tumor cells in Hodgkin lymphoma.
Leukemia & lymphoma May, 2010 | Pubmed ID: 20367572
Adverse events following infusion of T cells for adoptive immunotherapy: a 10-year experience.
Cytotherapy Oct, 2010 | Pubmed ID: 20429793
Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex).
Journal of immunotherapy (Hagerstown, Md. : 1997) Apr, 2010 | Pubmed ID: 20445351
Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects.
Blood Nov, 2010 | Pubmed ID: 20709906
How I treat adenovirus in hematopoietic stem cell transplant recipients.
Blood Dec, 2010 | Pubmed ID: 20837781
T-cell therapy: the next generation.
Expert review of hematology Apr, 2010 | Pubmed ID: 21083454
High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells.
Blood Mar, 2011 | Pubmed ID: 21278353
Good manufacturing practice-grade cytotoxic T lymphocytes specific for latent membrane proteins (LMP)-1 and LMP2 for patients with Epstein-Barr virus-associated lymphoma.
Cytotherapy May, 2011 | Pubmed ID: 21361747
PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2011 | Pubmed ID: 21772253
Engineered T cells for pancreatic cancer treatment.
HPB : the official journal of the International Hepato Pancreato Biliary Association Sep, 2011 | Pubmed ID: 21843265
Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2011 | Pubmed ID: 21908573
Cytotoxic T lymphocytes simultaneously targeting multiple tumor-associated antigens to treat EBV negative lymphoma.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2011 | Pubmed ID: 21915103
Production of good manufacturing practice-grade cytotoxic T lymphocytes specific for Epstein-Barr virus, cytomegalovirus and adenovirus to prevent or treat viral infections post-allogeneic hematopoietic stem cell transplant.
Cytotherapy Jan, 2012 | Pubmed ID: 22172091
Generation of Polyclonal CMV-specific T Cells for the Adoptive Immunotherapy of Glioblastoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) Feb, 2012 | Pubmed ID: 22306904
Oncolytic immunotherapy of advanced solid tumors with a CD40L expressing replicating adenovirus: assessment of safety and immunological responses in patients.
Cancer research Feb, 2012 | Pubmed ID: 22323527
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