Joshua Tam
Wellman Center for Photomedicine
Massachusetts General Hospital
Joshua Tam is an Instructor in Dermatology at the Wellman Center for Photomedicine, Massachusetts General Hospital. He received his PhD in Biomedical Engineering from the Harvard-MIT division of Health Sciences and Technology, then joined Rox Anderson’s lab at the Wellman Center as a post-doctoral fellow, where he was the lead scientist in developing a new technology to harvest autologous, full-thickness skin in the form of “microcolumns”. These microcolumns can be directly applied into wound beds to accelerate wound healing, similar to conventional autologous minced skin grafts, but with the key advantage that each donor wound is small enough to close spontaneously within days, and without any long-term donor site morbidity or scarring. He was awarded the 2016 Wound Healing Foundation 3M Fellowship for his work. This technology has led to an FDA-cleared device that is now in clinical use.
Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis.
Circulation research Oct, 2003 | Pubmed ID: 14525808
Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature.
Blood May, 2008 | Pubmed ID: 18256324
A mathematical model of murine metabolic regulation by leptin: energy balance and defense of a stable body weight.
Cell metabolism Jan, 2009 | Pubmed ID: 19117546
Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.
Journal of cellular physiology May, 2009 | Pubmed ID: 19170073
Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells.
PloS one , 2009 | Pubmed ID: 19333381
Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo.
The American journal of pathology Jul, 2009 | Pubmed ID: 19477947
Pretreatment with ablative fractional laser changes kinetics and biodistribution of topical 5-aminolevulinic acid (ALA) and methyl aminolevulinate (MAL).
Lasers in surgery and medicine Aug, 2014 | Pubmed ID: 24842112
Longitudinal, 3D in vivo imaging of sebaceous glands by coherent anti-stokes Raman scattering microscopy: normal function and response to cryotherapy.
The Journal of investigative dermatology Jan, 2015 | Pubmed ID: 25026458
Chimeric autologous/allogeneic constructs for skin regeneration.
Military medicine Aug, 2014 | Pubmed ID: 25102552
Fractional Skin Harvesting: Autologous Skin Grafting without Donor-site Morbidity.
Plastic and reconstructive surgery. Global open Sep, 2013 | Pubmed ID: 25289241
Selective Cryolysis of Sebaceous Glands.
The Journal of investigative dermatology Sep, 2015 | Pubmed ID: 25860384
Micro-fractional, directional skin tightening: A porcine model.
Lasers in surgery and medicine Mar, 2016 | Pubmed ID: 26627306
PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity.
Clinical cancer research : an official journal of the American Association for Cancer Research 06, 2016 | Pubmed ID: 26861455
Reconstitution of full-thickness skin by microcolumn grafting.
Journal of tissue engineering and regenerative medicine Oct, 2017 | Pubmed ID: 27296503
Laser-assisted delivery of synergistic combination chemotherapy in in vivo skin.
Journal of controlled release : official journal of the Controlled Release Society Apr, 2018 | Pubmed ID: 29454062
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