Manchester Cancer Research Centre Building,
Department Cancer Sciences,
Manchester Cancer Research Centre Building, Department Cancer Sciences
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Primary polyclonal human T lymphocytes targeted to carcino-embryonic antigens and neural cell adhesion molecule tumor antigens by CD3zeta-based chimeric immune receptors.
Journal of immunotherapy (Hagerstown, Md. : 1997) Mar-Apr, 2002 | Pubmed ID: 12074044
Cancer vaccines and immunotherapy.
British medical bulletin , 2002 | Pubmed ID: 12176857
Gene therapy of patient-derived T lymphocytes to target and eradicate colorectal hepatic metastases.
Diseases of the colon and rectum Jun, 2003 | Pubmed ID: 12794582
Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes.
Osteoarthritis and cartilage Jan, 2005 | Pubmed ID: 15639641
The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens.
Journal of immunotherapy (Hagerstown, Md. : 1997) May-Jun, 2005 | Pubmed ID: 15838376
Killing of non-Hodgkin lymphoma cells by autologous CD19 engineered T cells.
British journal of haematology May, 2005 | Pubmed ID: 15842655
Combination of vaccination and chimeric receptor expressing T cells provides improved active therapy of tumors.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2006 | Pubmed ID: 16982863
Cellular therapy of cancer symposium December 2nd-3rd 2006 Manchester, UK.
Cancer immunology, immunotherapy : CII Jun, 2007 | Pubmed ID: 17333180
Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma.
Cancer immunology, immunotherapy : CII May, 2008 | Pubmed ID: 17899077
Eotaxin-2 and colorectal cancer: a potential target for immune therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2007 | Pubmed ID: 17908961
CD4+ T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25+ T cells.
Cancer immunology, immunotherapy : CII Jun, 2008 | Pubmed ID: 18004564
Immunotherapy for gastrointestinal cancer: current status and strategies for improving efficacy.
Expert opinion on biological therapy Apr, 2008 | Pubmed ID: 18352844
The combination of cyclophosphamide and human T cells genetically engineered to target CD19 can eradicate established B-cell lymphoma.
British journal of haematology Jul, 2008 | Pubmed ID: 18477047
An MVA-based vaccine targeting the oncofetal antigen 5T4 in patients undergoing surgical resection of colorectal cancer liver metastases.
Journal of immunotherapy (Hagerstown, Md. : 1997) Nov-Dec, 2008 | Pubmed ID: 18833005
Immune evasion mechanisms in colorectal cancer liver metastasis patients vaccinated with TroVax (MVA-5T4).
Cancer immunology, immunotherapy : CII Oct, 2009 | Pubmed ID: 19221742
Vaccination of patients with metastatic renal cancer with modified vaccinia Ankara encoding the tumor antigen 5T4 (TroVax) given alongside interferon-alpha.
Journal of immunotherapy (Hagerstown, Md. : 1997) May, 2009 | Pubmed ID: 19342962
The second cellular therapy of cancer symposium, 27-29 March 2009, Milan, Italy.
Cancer immunology, immunotherapy : CII Jun, 2010 | Pubmed ID: 19669146
T cell-based immunotherapy of metastatic renal cell carcinoma: modest success and future perspective.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2009 | Pubmed ID: 19843660
Cytokine stimulation and the choice of promoter are critical factors for the efficient transduction of mouse T cells with HIV-1 vectors.
The journal of gene medicine Feb, 2010 | Pubmed ID: 20033928
Development of a flow cytometric co-immunoprecipitation technique for the study of multiple protein-protein interactions and its application to T-cell receptor analysis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Apr, 2010 | Pubmed ID: 20033991
Natural expression of the CD19 antigen impacts the long-term engraftment but not antitumor activity of CD19-specific engineered T cells.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2010 | Pubmed ID: 20089697
Modulation of lymphocyte regulation for cancer therapy: a phase II trial of tremelimumab in advanced gastric and esophageal adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2010 | Pubmed ID: 20179239
Development of adoptive cell therapy for cancer: a clinical perspective.
Human gene therapy Jun, 2010 | Pubmed ID: 20408760
Functional expression of secreted proteins from a bicistronic retroviral cassette based on foot-and-mouth disease virus 2A can be position dependent.
Human gene therapy Nov, 2010 | Pubmed ID: 20528679
Gene delivery of a mutant TGFβ3 reduces markers of scar tissue formation after cutaneous wounding.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2010 | Pubmed ID: 20736928
Tremelimumab (anti-CTLA4) mediates immune responses mainly by direct activation of T effector cells rather than by affecting T regulatory cells.
Clinical immunology (Orlando, Fla.) Jan, 2011 | Pubmed ID: 21056008
Targeted immunotherapy of cancer with CAR T cells: achievements and challenges.
Cancer immunology, immunotherapy : CII Jul, 2012 | Pubmed ID: 22527245
CAR-T cells and solid tumors: tuning T cells to challenge an inveterate foe.
Trends in molecular medicine Jul, 2012 | Pubmed ID: 22613370
Potential limitations of the NSG humanized mouse as a model system to optimize engineered human T cell therapy for cancer.
Human gene therapy methods Oct, 2013 | Pubmed ID: 23931270
Isolation of tumor antigen-specific single-chain variable fragments using a chimeric antigen receptor bicistronic retroviral vector in a Mammalian screening protocol.
Human gene therapy methods Dec, 2013 | Pubmed ID: 24028672
CAR T cells: driving the road from the laboratory to the clinic.
Immunological reviews Jan, 2014 | Pubmed ID: 24329792
Differential role of Th1 and Th2 cytokines in autotoxicity driven by CD19-specific second-generation chimeric antigen receptor T cells in a mouse model.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2014 | Pubmed ID: 24623129
Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens.
World journal of gastroenterology Apr, 2014 | Pubmed ID: 24744590
Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-α versus IFN-α.
Oncotarget Feb, 2015 | Pubmed ID: 25669986
Integrating radiation therapy with emerging systemic therapies: Lessons from a patient with cerebral radionecrosis, spinal cord myelopathy, and radiation pneumonitis.
Practical radiation oncology Mar-Apr, 2016 | Pubmed ID: 26723549
Randomized Open-Label Phase II Trial of Apitolisib (GDC-0980), a Novel Inhibitor of the PI3K/Mammalian Target of Rapamycin Pathway, Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 05, 2016 | Pubmed ID: 26951309
Adjuvant Weekly Girentuximab Following Nephrectomy for High-Risk Renal Cell Carcinoma: The ARISER Randomized Clinical Trial.
JAMA oncology Jul, 2017 | Pubmed ID: 27787547
The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity.
Cancer immunology, immunotherapy : CII Nov, 2017 | Pubmed ID: 28660319
Ex vivo expanded tumour-infiltrating lymphocytes from ovarian cancer patients release anti-tumour cytokines in response to autologous primary ovarian cancer cells.
Cancer immunology, immunotherapy : CII Oct, 2018 | Pubmed ID: 30039427
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