High Throughput Screening Facility
Meng Wu is an Assistant Professor in the Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York. He received his PhD in Biochemistry and Molecular Biology from Peking Union Medical College in China. His early studies involved chromatin biology and epigenetic regulation in neural differentiation, which uncovered the regulatory roles of histone chaperone, histone modifications and chromatin remodeling in neural differentiation. Dr. Wu had his postdoctoral training at the Icahn School of Medicine at Mount Sinai. He has a broad background in cell biology, development and genomics, with strong expertise in disease modeling and functional studies. Currently, his research focuses on mechanisms related to the pathogenesis of birth defects, utilizing animal models, organoids, and mouse and human pluripotent stem cells to elucidate signaling pathways, epigenetics and gene regulation in normal and abnormal developmental processes.
Inducible gene deletion in the entire cardiac conduction system using Hcn4-CreERT2 BAC transgenic mice.
Genesis (New York, N.Y. : 2000) Feb, 2014 | Pubmed ID: 24281837
Multifaceted roles of miR-1s in repressing the fetal gene program in the heart.
Cell research Mar, 2014 | Pubmed ID: 24481529
Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression.
PloS one , 2014 | Pubmed ID: 25010565
Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node.
Cell research Oct, 2014 | Pubmed ID: 25145359
Resonant waveguide grating for monitoring biomolecular interactions.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25859947
GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions.
Nature biotechnology Dec, 2015 | Pubmed ID: 26524661
Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration.
Cell stem cell Apr, 2016 | Pubmed ID: 27044474
Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016.
American journal of medical genetics. Part A May, 2017 | Pubmed ID: 28190301
Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice.
Disease models & mechanisms 05, 2019 | Pubmed ID: 31064775
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