Kathryn E. Saatman

Differential behavioral and histopathological responses to graded cortical impact injury in mice.

Classification of traumatic brain injury for targeted therapies.

Comparative neuroprotective effects of cyclosporin A and NIM811, a nonimmunosuppressive cyclosporin A analog, following traumatic brain injury.

Temporal and regional changes in IGF-1/IGF-1R signaling in the mouse brain after traumatic brain injury.

Calpain as a therapeutic target in traumatic brain injury.

miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease.

Targeting individual calpain isoforms for neuroprotection.

MicroRNAs in CNS injury: potential roles and therapeutic implications.

Rate of neurodegeneration in the mouse controlled cortical impact model is influenced by impactor tip shape: implications for mechanistic and therapeutic studies.

Posttraumatic mossy fiber sprouting is related to the degree of cortical damage in three mouse strains.

Genetic manipulation of cell death and neuroplasticity pathways in traumatic brain injury.

Calpastatin overexpression limits calpain-mediated proteolysis and behavioral deficits following traumatic brain injury.

Rit GTPase signaling promotes immature hippocampal neuronal survival.

Brain injury-induced proteolysis is reduced in a novel calpastatin-overexpressing transgenic mouse.

Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration.

Astrocyte-Specific Overexpression of Insulin-Like Growth Factor-1 Protects Hippocampal Neurons and Reduces Behavioral Deficits following Traumatic Brain Injury in Mice.

Ablation of matrix metalloproteinase-9 gene decreases cerebrovascular permeability and fibrinogen deposition post traumatic brain injury in mice.

Conditional overexpression of insulin-like growth factor-1 enhances hippocampal neurogenesis and restores immature neuron dendritic processes after traumatic brain injury.

Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin.

Regional neurodegeneration and gliosis are amplified by mild traumatic brain injury repeated at 24-hour intervals.

Phage display for identification of serum biomarkers of traumatic brain injury.

Repeated Closed Head Injury in Mice Results in Sustained Motor and Memory Deficits and Chronic Cellular Changes.

IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade.

Brain microvascular injury and white matter disease provoked by diabetes-associated hyperamylinemia.

Central Infusion of Insulin-Like Growth Factor-1 Increases Hippocampal Neurogenesis and Improves Neurobehavioral Function after Traumatic Brain Injury.

Pre-Clinical Testing of Therapies for Traumatic Brain Injury.

Assessment of systemic administration of PEGylated IGF-1 in a mouse model of traumatic brain injury.

Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment ("chemobrain").

Experimental Designs for Repeated Mild Traumatic Brain Injury: Challenges and Considerations.

Acute Mitochondrial Impairment Underlies Prolonged Cellular Dysfunction after Repeated Mild Traumatic Brain Injuries.

Noninvasive noncontact speckle contrast diffuse correlation tomography of cerebral blood flow in rats.

Fractionated mitochondrial magnetic separation for isolation of synaptic mitochondria from brain tissue.

Therapeutic potential of natural compounds from Chinese medicine in acute and subacute phases of ischemic stroke.

Insulin-like growth factor-1 overexpression increases long-term survival of posttrauma-born hippocampal neurons while inhibiting ectopic migration following traumatic brain injury.