Kathlyn Laval
Department of Molecular Biology
Princeton University
Dr. Kathlyn Laval, a virologist from Pasteur Institute with a PhD in Veterinary Sciences from Ghent University, is currently working as a postdoctoral researcher in the Enquist laboratory at the Department of Molecular Biology, Princeton University. During her postdoctoral research, she developed an animal model to study alphaherpesvirus-induced neuroinflammation. She developed her own research project starting from the writing of several grants (Life Sciences Research Foundation, Multiple Sclerosis and spinal cord injury grants, ...), IACUC protocols and the design of the experiments to the publication of 4 major scientific papers. Her work is funded by National Institute of Neurological Disorders and Stroke (NINDS). Within 7 years of reseach experience, she first-authored 8 publications and co-authored on another 11. As a long-term goal, she aims to continue her work on viral-induced neuroinflammation and neurodegenerative diseases, and ultimately to design innovative therapies.
Access to a main alphaherpesvirus receptor, located basolaterally in the respiratory epithelium, is masked by intercellular junctions.
Scientific reports 11, 2017 | Pubmed ID: 29192251
Abortigenic but Not Neurotropic Equine Herpes Virus 1 Modulates the Interferon Antiviral Defense.
Frontiers in cellular and infection microbiology , 2018 | Pubmed ID: 30258819
Equine Herpesvirus 1 Bridles T Lymphocytes To Reach Its Target Organs.
Journal of virology 04, 2019 | Pubmed ID: 30651370
Unravelling the first key steps in equine herpesvirus type 5 (EHV5) pathogenesis using ex vivo and in vitro equine models.
Veterinary research Feb, 2019 | Pubmed ID: 30777128
Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection.
Scientific reports 03, 2019 | Pubmed ID: 30886217
Beyond Gut Instinct: Metabolic Short-Chain Fatty Acids Moderate the Pathogenesis of Alphaherpesviruses.
Frontiers in microbiology , 2019 | Pubmed ID: 31024501
Deoxynivalenol, but not fumonisin B1, aflatoxin B1 or diesel exhaust particles disrupt integrity of the horse's respiratory epithelium and predispose it for equine herpesvirus type 1 infection.
Veterinary microbiology Jul, 2019 | Pubmed ID: 31213268
Equine herpesvirus 1 infection orchestrates the expression of chemokines in equine respiratory epithelial cells.
The Journal of general virology 11, 2019 | Pubmed ID: 31490114
Alphaherpesvirus infection of mice primes PNS neurons to an inflammatory state regulated by TLR2 and type I IFN signaling.
PLoS pathogens 11, 2019 | Pubmed ID: 31675371
An Alphaherpesvirus Exploits Antimicrobial β-Defensins To Initiate Respiratory Tract Infection.
Journal of virology Mar, 2020 | Pubmed ID: 31996426
The Neuropathic Itch Caused by Pseudorabies Virus.
Pathogens (Basel, Switzerland) Mar, 2020 | Pubmed ID: 32244386
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