Department of Clinical Medicine
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Glass-windowed ultrasound transducers.
Ultrasonics May, 2016 | Pubmed ID: 26938326
A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer.
Journal of controlled release : official journal of the Controlled Release Society 12, 2016 | Pubmed ID: 27744037
Sonoporation with Acoustic Cluster Therapy (ACT®) induces transient tumour volume reduction in a subcutaneous xenograft model of pancreatic ductal adenocarcinoma.
Journal of controlled release : official journal of the Controlled Release Society 01, 2017 | Pubmed ID: 27871988
Intracellular Signaling in Key Pathways Is Induced by Treatment with Ultrasound and Microbubbles in a Leukemia Cell Line, but Not in Healthy Peripheral Blood Mononuclear Cells.
Pharmaceutics Jul, 2019 | Pubmed ID: 31284599
Intracellular Cytidine Deaminase Regulates Gemcitabine Metabolism in Pancreatic Cancer Cell Lines.
Drug metabolism and disposition: the biological fate of chemicals 03, 2020 | Pubmed ID: 31871136
Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells.
Pharmaceutics Feb, 2020 | Pubmed ID: 32046005
Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells.
Pharmaceutics Nov, 2020 | Pubmed ID: 33171947
Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model.
Cancer biology & therapy 03, 2021 | Pubmed ID: 33691611
Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys.
Pharmaceutics Nov, 2021 | Pubmed ID: 34959319
SonoVue vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?
Pharmaceutics Jan, 2022 | Pubmed ID: 35056994
Charissa Poon1,2,
Melina Mühlenpfordt*,3,
Marieke Olsman*,3,
Spiros Kotopoulis4,5,
Catharina de Lange Davies3,
Kullervo Hynynen1,2,6
1Physical Sciences Platform, Sunnybrook Research Institute,
2Institute of Biomedical Engineering, University of Toronto,
3Department of Physics, Norwegian University of Science and Technology,
4Department of Clinical Medicine, University of Bergen,
5, Exact Therapeutics AS,
6Department of Medical Biophysics, University of Toronto
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