Department of Molecular and Cellular Biology
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The formation of helical tubular vesicles by binary monolayers containing a nickel-chelating lipid and phosphoinositides in the presence of basic polypeptides.
Chemistry and physics of lipids Jan, 2002 | Pubmed ID: 11841829
An Arg/Lys-->Gln mutant of recombinant murine myelin basic protein as a mimic of the deiminated form implicated in multiple sclerosis.
Protein expression and purification Jul, 2002 | Pubmed ID: 12135568
Interactions of the 18.5-kDa isoform of myelin basic protein with Ca(2+)-calmodulin: in vitro studies using fluorescence microscopy and spectroscopy.
Biochemistry and cell biology = Biochimie et biologie cellulaire , 2002 | Pubmed ID: 12234092
Interactions of the 18.5 kDa isoform of myelin basic protein with Ca2+-calmodulin: in vitro studies using gel shift assays.
Molecular and cellular biochemistry Dec, 2002 | Pubmed ID: 12482024
Expression and properties of the recombinant murine Golli-myelin basic protein isoform J37.
Journal of neuroscience research Mar, 2003 | Pubmed ID: 12605403
Terminal deletion mutants of myelin basic protein: new insights into self-association and phospholipid interactions.
Micron (Oxford, England : 1993) , 2003 | Pubmed ID: 12694855
Membrane-anchoring and charge effects in the interaction of myelin basic protein with lipid bilayers studied by site-directed spin labeling.
The Journal of biological chemistry Aug, 2003 | Pubmed ID: 12748174
Interaction of the 18.5-kD isoform of myelin basic protein with Ca2+ -calmodulin: effects of deimination assessed by intrinsic Trp fluorescence spectroscopy, dynamic light scattering, and circular dichroism.
Protein science : a publication of the Protein Society Jul, 2003 | Pubmed ID: 12824496
Molecular dynamics exposes alpha-helices in myelin basic protein.
Journal of molecular modeling Oct, 2003 | Pubmed ID: 12898292
Myelin basic protein has multiple calmodulin-binding sites.
Biochemical and biophysical research communications Aug, 2003 | Pubmed ID: 12901870
Translocation of group 1 capsular polysaccharide in Escherichia coli serotype K30. Structural and functional analysis of the outer membrane lipoprotein Wza.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 14522970
An immunodominant epitope of myelin basic protein is an amphipathic alpha-helix.
The Journal of biological chemistry Feb, 2004 | Pubmed ID: 14630913
Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis.
Micron (Oxford, England : 1993) , 2004 | Pubmed ID: 15219899
Backbone resonance assignments of the 18.5 kDa isoform of murine myelin basic protein (MBP).
Journal of biomolecular NMR Aug, 2004 | Pubmed ID: 15243191
Electron paramagnetic resonance spectroscopy and molecular modelling of the interaction of myelin basic protein (MBP) with calmodulin (CaM)-diversity and conformational adaptability of MBP CaM-targets.
Journal of structural biology Dec, 2004 | Pubmed ID: 15522783
Charge effects modulate actin assembly by classic myelin basic protein isoforms.
Biochemical and biophysical research communications Apr, 2005 | Pubmed ID: 15721315
Effect of arginine loss in myelin basic protein, as occurs in its deiminated charge isoform, on mediation of actin polymerization and actin binding to a lipid membrane in vitro.
Biochemistry Mar, 2005 | Pubmed ID: 15736962
Regulation of fish gill Na(+)-K(+)-ATPase by selective sulfatide-enriched raft partitioning during seawater adaptation.
The Journal of biological chemistry Nov, 2005 | Pubmed ID: 16096276
Assembly of tubulin by classic myelin basic protein isoforms and regulation by post-translational modification.
Biochemistry Dec, 2005 | Pubmed ID: 16342957
Solution NMR structure of an immunodominant epitope of myelin basic protein. Conformational dependence on environment of an intrinsically unstructured protein.
The FEBS journal Feb, 2006 | Pubmed ID: 16420483
Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2006 | Pubmed ID: 16537438
Structural studies of FlaA1 from Helicobacter pylori reveal the mechanism for inverting 4,6-dehydratase activity.
The Journal of biological chemistry Aug, 2006 | Pubmed ID: 16651261
A tale of two citrullines--structural and functional aspects of myelin basic protein deimination in health and disease.
Neurochemical research Feb, 2007 | Pubmed ID: 16900293
White matter rafting--membrane microdomains in myelin.
Neurochemical research Feb, 2007 | Pubmed ID: 17031566
Purification and spectroscopic characterization of the recombinant BG21 isoform of murine golli myelin basic protein.
Journal of neuroscience research Feb, 2007 | Pubmed ID: 17131428
Partitioning of myelin basic protein into membrane microdomains in a spontaneously demyelinating mouse model for multiple sclerosis.
Biochemistry and cell biology = Biochimie et biologie cellulaire Dec, 2006 | Pubmed ID: 17215885
Molecular "negativity" may underlie multiple sclerosis: role of the myelin basic protein family in the pathogenesis of MS.
International review of neurobiology , 2007 | Pubmed ID: 17531841
The BG21 isoform of Golli myelin basic protein is intrinsically disordered with a highly flexible amino-terminal domain.
Biochemistry Aug, 2007 | Pubmed ID: 17676872
Solid-state NMR spectroscopy of 18.5 kDa myelin basic protein reconstituted with lipid vesicles: spectroscopic characterisation and spectral assignments of solvent-exposed protein fragments.
Biochimica et biophysica acta Dec, 2007 | Pubmed ID: 17920035
Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.
Biochemistry Jan, 2008 | Pubmed ID: 18067320
Dipolar chemical shift correlation spectroscopy for homonuclear carbon distance measurements in proteins in the solid state: application to structure determination and refinement.
Journal of the American Chemical Society Jan, 2008 | Pubmed ID: 18072776
Backbone dynamics of the 18.5 kDa isoform of myelin basic protein reveals transient alpha-helices and a calmodulin-binding site.
Biophysical journal Jun, 2008 | Pubmed ID: 18326633
Solution NMR and CD spectroscopy of an intrinsically disordered, peripheral membrane protein: evaluation of aqueous and membrane-mimetic solvent conditions for studying the conformational adaptability of the 18.5 kDa isoform of myelin basic protein (MBP).
European biophysics journal : EBJ Jul, 2008 | Pubmed ID: 18449534
Expression and purification of the active variant of recombinant murine Golli-interacting protein (GIP)--characterization of its phosphatase activity and interaction with Golli-BG21.
Protein expression and purification Nov, 2008 | Pubmed ID: 18625321
Myelin basic protein as a "PI(4,5)P2-modulin": a new biological function for a major central nervous system protein.
Biochemistry Sep, 2008 | Pubmed ID: 18767817
Kinetics of human peptidylarginine deiminase 2 (hPAD2)--reduction of Ca2+ dependence by phospholipids and assessment of proposed inhibition by paclitaxel side chains.
Biochemistry and cell biology = Biochimie et biologie cellulaire Oct, 2008 | Pubmed ID: 18923545
Myelin basic protein co-distributes with other PI(4,5)P2-sequestering proteins in Triton X-100 detergent-resistant membrane microdomains.
Neuroscience letters Jan, 2009 | Pubmed ID: 19026719
Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system.
Disease models & mechanisms Nov-Dec, 2008 | Pubmed ID: 19093029
Induced secondary structure and polymorphism in an intrinsically disordered structural linker of the CNS: solid-state NMR and FTIR spectroscopy of myelin basic protein bound to actin.
Biophysical journal Jan, 2009 | Pubmed ID: 19134474
Influence of membrane surface charge and post-translational modifications to myelin basic protein on its ability to tether the Fyn-SH3 domain to a membrane in vitro.
Biochemistry Mar, 2009 | Pubmed ID: 19178193
The classic basic protein of myelin--conserved structural motifs and the dynamic molecular barcode involved in membrane adhesion and protein-protein interactions.
Current protein & peptide science Jun, 2009 | Pubmed ID: 19519451
NMR assignment of an intrinsically disordered protein under physiological conditions: the 18.5 kDa isoform of murine myelin basic protein.
Biomolecular NMR assignments Jul, 2007 | Pubmed ID: 19636827
Structural polymorphism and multifunctionality of myelin basic protein.
Biochemistry Sep, 2009 | Pubmed ID: 19642704
Divalent cations induce a compaction of intrinsically disordered myelin basic protein.
Biochemical and biophysical research communications Jan, 2010 | Pubmed ID: 19903451
Misincorporation of the proline homologue Aze (azetidine-2-carboxylic acid) into recombinant myelin basic protein.
Phytochemistry Apr, 2010 | Pubmed ID: 20064647
The interaction of zinc with membrane-associated 18.5 kDa myelin basic protein: an attenuated total reflectance-Fourier transform infrared spectroscopic study.
Amino acids Aug, 2010 | Pubmed ID: 20169373
Fuzzy complexes of myelin basic protein: NMR spectroscopic investigations of a polymorphic organizational linker of the central nervous system.
Biochemistry and cell biology = Biochimie et biologie cellulaire Apr, 2010 | Pubmed ID: 20453917
Interaction of myelin basic protein with actin in the presence of dodecylphosphocholine micelles.
Biochemistry Aug, 2010 | Pubmed ID: 20593886
Solid-state NMR spectroscopy of membrane-associated myelin basic protein--conformation and dynamics of an immunodominant epitope.
Biophysical journal Aug, 2010 | Pubmed ID: 20713009
Secondary structure and solvent accessibility of a calmodulin-binding C-terminal segment of membrane-associated myelin basic protein.
Biochemistry Oct, 2010 | Pubmed ID: 20831157
Interactions of intrinsically disordered Thellungiella salsuginea dehydrins TsDHN-1 and TsDHN-2 with membranes - synergistic effects of lipid composition and temperature on secondary structure.
Biochemistry and cell biology = Biochimie et biologie cellulaire Oct, 2010 | Pubmed ID: 20921991
Zinc induces disorder-to-order transitions in free and membrane-associated Thellungiella salsuginea dehydrins TsDHN-1 and TsDHN-2: a solution CD and solid-state ATR-FTIR study.
Amino acids May, 2011 | Pubmed ID: 20924623
Copper uptake induces self-assembly of 18.5 kDa myelin basic protein (MBP).
Biophysical journal Nov, 2010 | Pubmed ID: 21044600
Conformational choreography of a molecular switch region in myelin basic protein--molecular dynamics shows induced folding and secondary structure type conversion upon threonyl phosphorylation in both aqueous and membrane-associated environments.
Biochimica et biophysica acta Mar, 2011 | Pubmed ID: 21130728
Myelin basic protein binds microtubules to a membrane surface and to actin filaments in vitro: effect of phosphorylation and deimination.
Biochimica et biophysica acta Mar, 2011 | Pubmed ID: 21185260
Classical 18.5-and 21.5-kDa isoforms of myelin basic protein inhibit calcium influx into oligodendroglial cells, in contrast to golli isoforms.
Journal of neuroscience research Jan, 2011 | Pubmed ID: 21234892
Classical 18.5-and 21.5-kDa isoforms of myelin basic protein inhibit calcium influx into oligodendroglial cells, in contrast to golli isoforms.
Journal of neuroscience research Apr, 2011 | Pubmed ID: 21312222
Proline substitutions and threonine pseudophosphorylation of the SH3 ligand of 18.5-kDa myelin basic protein decrease its affinity for the Fyn-SH3 domain and alter process development and protein localization in oligodendrocytes.
Journal of neuroscience research Jan, 2012 | Pubmed ID: 21887699
Structured functional domains of myelin basic protein: cross talk between actin polymerization and Ca(2+)-dependent calmodulin interaction.
Biophysical journal Sep, 2011 | Pubmed ID: 21889463
Phosphorylation of Thellungiella salsuginea dehydrins TsDHN-1 and TsDHN-2 facilitates cation-induced conformational changes and actin assembly.
Biochemistry Nov, 2011 | Pubmed ID: 21970344
Classic 18.5- and 21.5-kDa Myelin Basic Protein Isoforms Associate with Cytoskeletal and SH3-Domain Proteins in the Immortalized N19-Oligodendroglial Cell Line Stimulated by Phorbol Ester and IGF-1.
Neurochemical research Jan, 2012 | Pubmed ID: 22249765
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