Physiology,
Exercise and Nutrition Research Group,
Physiology, Exercise and Nutrition Research Group
My work aims to make people healthier. I do this through: (1) research on physical activity interventions; (2) research on genetic and epigenetic aspects of response to exercise/nutrition; and (3) public engagement activities to spread understanding of biomedical science and health research.
My physical activity research focuses on the popular Daily Mile schools physical activity intervention – now done by ~50% of Scottish primary schools. I co-lead a multidisciplinary team of academics including physiologists, developmental psychologists and behaviour change experts. Our projects have attracted a great deal of attention from a wide range of organisations and individuals both at home and abroad including governments, policy makers, television, newspapers, teachers, parents and academics.
Why are we not all the same? Whilst increasing physical activity will improve population level health, the same amount of physical activity will not work equally well for all individuals. I have several genetic and epigenetic projects with the goal of tailoring of health advice to individuals. These focus on understanding inter-individual differences and gender differences in the physiology that underpins our health, disease and sports performance. I am a core member of international consortia in these areas (e.g. Athlome or ELITE).
Throughout my career, I have sought out opportunities to be involved in and drive public engagement. Recently, I have been able to combine this with my physical activity research using a Citizen Science approach to collect data from >11,000 school children. Whatever our research areas, we need to communicate our findings in a way that can be understood by the largest number of people to achieve the maximum impact.
Plasma microRNA levels differ between endurance and strength athletes.
PloS one , 2015 | Pubmed ID: 25881132
Exercise-conditioned plasma attenuates nuclear concentrations of DNA methyltransferase 3B in human peripheral blood mononuclear cells.
Physiological reports Dec, 2015 | Pubmed ID: 26660547
Athlome Project Consortium: a concerted effort to discover genomic and other "omic" markers of athletic performance.
Physiological genomics Mar, 2016 | Pubmed ID: 26715623
Tour de France Champions born or made: where do we take the genetics of performance?
Journal of sports sciences Jul, 2017 | Pubmed ID: 27498724
The Daily Mile makes primary school children more active, less sedentary and improves their fitness and body composition: a quasi-experimental pilot study.
BMC medicine May, 2018 | Pubmed ID: 29743076
The Daily Mile: What factors are associated with its implementation success?
PloS one , 2018 | Pubmed ID: 30286175
Response to Daly-Smith et al.'s commentary on 'The Daily Mile makes primary school children more active, less sedentary and improves their fitness and body composition: a quasi-experimental pilot study'.
BMC medicine 05, 2019 | Pubmed ID: 31113425
A citizen science study of short physical activity breaks at school: improvements in cognition and wellbeing with self-paced activity.
BMC medicine 03, 2020 | Pubmed ID: 32178667
Human skeletal muscle metabolic responses to 6 days of high-fat overfeeding are associated with dietary n-3PUFA content and muscle oxidative capacity.
Physiological reports 08, 2020 | Pubmed ID: 32845565
Relationship between insulin sensitivity and menstrual cycle is modified by BMI, fitness and physical activity in NHANES.
The Journal of clinical endocrinology and metabolism Jun, 2021 | Pubmed ID: 34111293
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