Department of Orthopedics,
Center for Musculoskeletal Research,
Department of Orthopedics, Center for Musculoskeletal Research
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Recent advances in gene delivery for structural bone allografts.
Tissue engineering Aug, 2007 | Pubmed ID: 17518728
Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography.
Arthritis and rheumatism Dec, 2007 | Pubmed ID: 18050199
Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2008 | Pubmed ID: 18180771
A perspective: engineering periosteum for structural bone graft healing.
Clinical orthopaedics and related research Aug, 2008 | Pubmed ID: 18509709
Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins.
The Journal of biological chemistry Aug, 2008 | Pubmed ID: 18567580
Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging.
Arthritis and rheumatism Jul, 2008 | Pubmed ID: 18576355
The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings.
Biomaterials Oct, 2008 | Pubmed ID: 18590929
Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Sep, 2010 | Pubmed ID: 20187115
Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw.
Annals of the New York Academy of Sciences Mar, 2010 | Pubmed ID: 20392222
Evaluation of dense polylactic acid/beta-tricalcium phosphate scaffolds for bone tissue engineering.
Journal of biomedical materials research. Part A Dec, 2010 | Pubmed ID: 20725979
Teriparatide therapy and beta-tricalcium phosphate enhance scaffold reconstruction of mouse femoral defects.
Tissue engineering. Part A Feb, 2011 | Pubmed ID: 20807012
A novel animal model for studying silicone gel-related capsular contracture.
Plastic and reconstructive surgery Nov, 2010 | Pubmed ID: 21042104
Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur.
Molecular therapy : the journal of the American Society of Gene Therapy Aug, 2011 | Pubmed ID: 21206485
TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Sep, 2011 | Pubmed ID: 21445993
The impact of Smad3 loss of function on TGF-β signaling and radiation-induced capsular contracture.
Plastic and reconstructive surgery Jun, 2011 | Pubmed ID: 21617460
Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: implications for insufficiency fracture risk.
Arthritis and rheumatism Nov, 2012 | Pubmed ID: 22832945
PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Mar, 2013 | Pubmed ID: 22991274
Engineering superficial zone features in tissue engineered cartilage.
Biotechnology and bioengineering May, 2013 | Pubmed ID: 23239161
Gene expression analysis of the pleiotropic effects of TGF-β1 in an in vitro model of flexor tendon healing.
PloS one , 2012 | Pubmed ID: 23251524
Bone fragility beyond strength and mineral density: Raman spectroscopy predicts femoral fracture toughness in a murine model of rheumatoid arthritis.
Journal of biomechanics Feb, 2013 | Pubmed ID: 23261243
Comparison of an all-inside suture technique with traditional pull-out suture and suture anchor repair techniques for flexor digitorum profundus attachment to bone.
The Journal of hand surgery Jun, 2013 | Pubmed ID: 23578439
Cellular and molecular factors in flexor tendon repair and adhesions: a histological and gene expression analysis.
Connective tissue research , 2013 | Pubmed ID: 23586515
Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur.
Bone Nov, 2013 | Pubmed ID: 23954757
Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.
Bone Mar, 2014 | Pubmed ID: 24316420
The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice.
Biomaterials Mar, 2014 | Pubmed ID: 24393269
A mouse model of flexor tendon repair.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 24482166
3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration.
Biomaterials Apr, 2014 | Pubmed ID: 24529628
Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment.
Bone May, 2014 | Pubmed ID: 24530870
Tendon repair is compromised in a high fat diet-induced mouse model of obesity and type 2 diabetes.
PloS one , 2014 | Pubmed ID: 24658034
Freeze-dried allograft-mediated gene or protein delivery of growth and differentiation factor 5 reduces reconstructed murine flexor tendon adhesions.
Journal of tissue engineering , 2014 | Pubmed ID: 24812579
TGF-β1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair.
Journal of cellular physiology Feb, 2015 | Pubmed ID: 24962629
Parathyroid hormone 1-34 enhances extracellular matrix deposition and organization during flexor tendon repair.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Jan, 2015 | Pubmed ID: 25266795
Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength.
Bone Mar, 2015 | Pubmed ID: 25446888
A novel murine model of established Staphylococcal bone infection in the presence of a fracture fixation plate to study therapies utilizing antibiotic-laden spacers after revision surgery.
Bone Mar, 2015 | Pubmed ID: 25459073
Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulation.
Bone Apr, 2015 | Pubmed ID: 25527421
Development of antisense oligonucleotide (ASO) technology against Tgf-β signaling to prevent scarring during flexor tendon repair.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Jun, 2015 | Pubmed ID: 25761254
3D printed bioceramics for dual antibiotic delivery to treat implant-associated bone infection.
European cells & materials Nov, 2015 | Pubmed ID: 26535494
Biomaterials approaches to treating implant-associated osteomyelitis.
Biomaterials Mar, 2016 | Pubmed ID: 26724454
NOTCH signaling in skeletal progenitors is critical for fracture repair.
The Journal of clinical investigation Apr, 2016 | Pubmed ID: 26950423
3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery.
Annals of biomedical engineering 01, 2017 | Pubmed ID: 27324800
Evidence of Staphylococcus Aureus Deformation, Proliferation, and Migration in Canaliculi of Live Cortical Bone in Murine Models of Osteomyelitis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research May, 2017 | Pubmed ID: 27933662
Sensitivity of spatially offset Raman spectroscopy (SORS) to subcortical bone tissue.
Journal of biophotonics Aug, 2017 | Pubmed ID: 28464501
In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs.
Science translational medicine May, 2017 | Pubmed ID: 28515335
Diblock Copolymer Hydrophobicity Facilitates Efficient Gene Silencing and Cytocompatible Nanoparticle-Mediated siRNA Delivery to Musculoskeletal Cell Types.
Biomacromolecules Nov, 2017 | Pubmed ID: 28960967
High dose teriparatide (rPTH1-34) therapy increases callus volume and enhances radiographic healing at 8-weeks in a massive canine femoral allograft model.
PloS one , 2017 | Pubmed ID: 29020057
Teriparatide (human PTH) compensates for impaired fracture healing in COX-2 deficient mice.
Bone 05, 2018 | Pubmed ID: 29408411
Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy.
Scientific reports Apr, 2018 | Pubmed ID: 29643421
Spatially offset Raman spectroscopy for bone strength prediction.
Biomedical optics express Oct, 2018 | Pubmed ID: 30319902
A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against Staphylococcus aureus Small-Colony Variants.
mSphere 10, 2018 | Pubmed ID: 30381352
Calcium Phosphate Spacers for the Local Delivery of Sitafloxacin and Rifampin to Treat Orthopedic Infections: Efficacy and Proof of Concept in a Mouse Model of Single-Stage Revision of Device-Associated Osteomyelitis.
Pharmaceutics Feb, 2019 | Pubmed ID: 30813284
An in vitro platform for elucidating the molecular genetics of S. aureus invasion of the osteocyte lacuno-canalicular network during chronic osteomyelitis.
Nanomedicine : nanotechnology, biology, and medicine 10, 2019 | Pubmed ID: 31247310
Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing.
Scientific reports 07, 2019 | Pubmed ID: 31358843
Transcriptomic Analysis of Cellular Pathways in Healing Flexor Tendons of Plasminogen Activator Inhibitor 1 (PAI-1/Serpine1) Null Mice.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 01, 2020 | Pubmed ID: 31424116
Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy".
Bone research , 2019 | Pubmed ID: 31646012
What Regions of the Distal Clavicle Have the Greatest Bone Mineral Density and Cortical Thickness? A Cadaveric Study.
Clinical orthopaedics and related research Dec, 2019 | Pubmed ID: 31764342
Effects of tamoxifen on tendon homeostasis and healing: Considerations for the use of tamoxifen-inducible mouse models.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 07, 2021 | Pubmed ID: 32485026
Peritalar Kinematics With Combined Deltoid-Spring Ligament Reconstruction in Simulated Advanced Adult Acquired Flatfoot Deformity.
Foot & ankle international Sep, 2020 | Pubmed ID: 32495639
The Effects of Splitting an Above Elbow Cast: A biomechanical study.
Injury Aug, 2020 | Pubmed ID: 32536528
Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice.
PLoS pathogens 10, 2020 | Pubmed ID: 33091079
A Mouse Femoral Ostectomy Model to Assess Bone Graft Substitutes.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 33197009
NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival.
Science signaling 11, 2020 | Pubmed ID: 33203721
Improved prediction of femoral fracture toughness in mice by combining standard medical imaging with Raman spectroscopy.
Journal of biomechanics 02, 2021 | Pubmed ID: 33485148
A Biomechanical, Cadaveric Evaluation of Single- Versus Double-Row Repair Techniques on Stability of Bony Bankart Lesions.
The American journal of sports medicine 03, 2021 | Pubmed ID: 33544626
Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis.
Frontiers in microbiology , 2021 | Pubmed ID: 34484165
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