Jianan Y. Qu
Department of Electronic and Computer Engineering,
State Key Laboratory of Molecular Neuroscience,
Center of Systems Biology and Human Health,
Molecular Neuroscience Center
The Hong Kong University of Science and Technology
Jianan Qu is a professor of Biomedical Engineering Program, Department of Electronic and Computer Engineering, the Hong Kong University of Science and Technology. He received BS in optical engineering from Huazhong University of Science and Technology and PhD in optics science from Chinese Academy of Sciences. After that he worked as post-doctoral fellow in University of California at Irvine and British Columbia Cancer Research Centre, and as a staff scientist with Ontario Cancer Institute.
During Dr. Qu’s post-doctoral training he developed a keen focus on research in biophotoincs, an emerging field of science and technology, representing the convergence of photonics with the life sciences. The newly emerging optical microscopy tools promise to make major contributions in visualizing biological processes. Qu’s Lab is dedicated to develop novel and powerful optical bio-imaging techniques and to apply them to unravel dynamic behaviors of bio-molecules in live cells and organisms.
He is elected fellows of OPTICA (formerly Optical Society of America) and SPIE (Society of Photo-Optical Instrumentation Engineers). His major research contributions have been in the development of advanced optical technology for biological research and medical diagnosis.
Preliminary study of in vivo autofluorescence of nasopharyngeal carcinoma and normal tissue.
Lasers in surgery and medicine , 2000 | Pubmed ID: 10861698
Fluorescence spectral imaging for characterization of tissue based on multivariate statistical analysis.
Journal of the Optical Society of America. A, Optics, image science, and vision Sep, 2002 | Pubmed ID: 12216876
Concentration measurements of multiple analytes in human sera by near-infrared laser Raman spectroscopy.
Applied optics Sep, 1999 | Pubmed ID: 18324058
Excitation-and-collection geometry insensitive fluorescence imaging of tissue-simulating turbid media.
Applied optics Jul, 2000 | Pubmed ID: 18349903
In Vivo nonlinear optical imaging of immune responses: tissue injury and infection.
Biophysical journal Nov, 2014 | Pubmed ID: 25418312
Temporal-Spatial Resolution Fate Mapping Reveals Distinct Origins for Embryonic and Adult Microglia in Zebrafish.
Developmental cell Sep, 2015 | Pubmed ID: 26418294
Multimodal nonlinear optical microscopy reveals critical role of kinesin-1 in cartilage development.
Biomedical optics express Mar, 2017 | Pubmed ID: 28663865
Adult zebrafish Langerhans cells arise from hematopoietic stem/progenitor cells.
eLife 06, 2018 | Pubmed ID: 29905527
In vivo single-cell lineage tracing in zebrafish using high-resolution infrared laser-mediated gene induction microscopy.
eLife 01, 2020 | Pubmed ID: 31904340
IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer's Disease.
Cell reports 04, 2020 | Pubmed ID: 32320664
Adaptive optics two-photon microscopy enables near-diffraction-limited and functional retinal imaging in vivo.
Light, science & applications , 2020 | Pubmed ID: 32411364
Lightening the way of hematopoiesis: Infrared laser-mediated lineage tracing with high spatial-temporal resolution.
Experimental hematology 05, 2020 | Pubmed ID: 32437907
Adaptive optics two-photon endomicroscopy enables deep-brain imaging at synaptic resolution over large volumes.
Science advances Sep, 2020 | Pubmed ID: 32998883
Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 01, 2021 | Pubmed ID: 33443211
Study of neurovascular coupling by using mesoscopic and microscopic imaging.
iScience Oct, 2021 | Pubmed ID: 34693226
In vivo Imaging of Biological Tissues with Combined Two-Photon Fluorescence and Stimulated Raman Scattering Microscopy
1Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology,
2State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology,
3Center of Systems Biology and Human Health, The Hong Kong University of Science and Technology,
4Molecular Neuroscience Center, The Hong Kong University of Science and Technology,
5Department of Biology, School of Life Sciences, Southern University of Science and Technology
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