Molecular Biology and Biochemistry Department,
Molecular Biophysics Program
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Lyme disease-causing Borrelia species encode multiple lipoproteins homologous to peptide-binding proteins of ABC-type transporters.
Infection and immunity Sep, 1998 | Pubmed ID: 9712756
Regulation of Escherichia coli secA by cellular protein secretion proficiency requires an intact gene X signal sequence and an active translocon.
Journal of bacteriology Oct, 1998 | Pubmed ID: 9748461
Characterization of Borrelia burgdorferi BlyA and BlyB proteins: a prophage-encoded holin-like system.
Journal of bacteriology Dec, 2000 | Pubmed ID: 11073925
Translocon "pulling" of nascent SecM controls the duration of its translational pause and secretion-responsive secA regulation.
Journal of bacteriology Nov, 2003 | Pubmed ID: 14594848
Role of a conserved glutamate residue in the Escherichia coli SecA ATPase mechanism.
The Journal of biological chemistry Apr, 2005 | Pubmed ID: 15710614
In vivo membrane topology of Escherichia coli SecA ATPase reveals extensive periplasmic exposure of multiple functionally important domains clustering on one face of SecA.
The Journal of biological chemistry Feb, 2007 | Pubmed ID: 17166834
Mapping of the signal peptide-binding domain of Escherichia coli SecA using Förster resonance energy transfer.
Biochemistry Feb, 2010 | Pubmed ID: 20025247
Mapping of the SecA·SecY and SecA·SecG interfaces by site-directed in vivo photocross-linking.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21317284
Characterization of the Escherichia coli SecA signal peptide-binding site.
Journal of bacteriology Jan, 2012 | Pubmed ID: 22056930
The variable subdomain of Escherichia coli SecA functions to regulate SecA ATPase activity and ADP release.
Journal of bacteriology May, 2012 | Pubmed ID: 22389482
Defining the solution state dimer structure of Escherichia coli SecA using Förster resonance energy transfer.
Biochemistry Apr, 2013 | Pubmed ID: 23484952
Determination of the Oligomeric State of SecYEG Protein Secretion Channel Complex Using in Vivo Photo- and Disulfide Cross-linking.
The Journal of biological chemistry Mar, 2016 | Pubmed ID: 26747607
The SecA protein deeply penetrates into the SecYEG channel during insertion, contacting most channel transmembrane helices and periplasmic regions.
The Journal of biological chemistry 12, 2017 | Pubmed ID: 28986446
Substrate Proteins Take Shape at an Improved Bacterial Translocon.
Journal of bacteriology 01, 2019 | Pubmed ID: 30322856
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