Department of Genetics,
Cell Biology and Development,
Developmental Biology Center,
Department of Genetics, Cell Biology and Development
Julaine Roffers-Agarwal is a senior scientist in the laboratory of Dr. Laura Gammill in the Department of Genetics, Cell Biology and Development at the University of Minnesota. She earned her B.S. in Biological Sciences from the University of Southern California, followed by a Masters of Science in Biological Sciences from the University of Wisconsin-Milwaukee, and a Ph.D. in Molecular, Cellular, Developmental Biology and Genetics from the University of Minnesota.
Dr. Roffers-Agarwal has developed skills in early vertebrate embryological development manipulation and observation. Her graduate work in Jeffrey Miller's lab involved examining the molecular mechanisms that impacted Xenopus laevis gastrulation and neurulation, including training with international leaders in developmental biology at the Marine Biological Laboratory. She then moved to the Gammill lab for postdoctoral studies and subsequent senior scientist position, using both mouse and chicken models to dissect mechanisms that control neural crest induction and migration using a combination of genetic, molecular, biochemical, and embryological manipulation techniques. Her more than a decade of work has uncovered novel neural crest biology including factors governing cell-cell signaling, phosphorylation, and lysine methylation.
Regulation of actin cytoskeleton architecture by Eps8 and Abi1.
BMC cell biology Oct, 2005 | Pubmed ID: 16225669
Enabled (Xena) regulates neural plate morphogenesis, apical constriction, and cellular adhesion required for neural tube closure in Xenopus.
Developmental biology Feb, 2008 | Pubmed ID: 18201691
Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation.
Development (Cambridge, England) Jun, 2009 | Pubmed ID: 19403658
Division of labor during trunk neural crest development.
Developmental biology Aug, 2010 | Pubmed ID: 20399766
Paladin is an antiphosphatase that regulates neural crest cell formation and migration.
Developmental biology Nov, 2012 | Pubmed ID: 22926139
DNA methyltransferase 3b is dispensable for mouse neural crest development.
PloS one , 2012 | Pubmed ID: 23094090
Embryological and Genetic Manipulation of Chick Development.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30737687
Profiling NSD3-dependent neural crest gene expression reveals known and novel candidate regulatory factors.
Developmental biology 07, 2021 | Pubmed ID: 33705737
The lysine methyltransferase SETD2 is a dynamically expressed regulator of early neural crest development.
Genesis (New York, N.Y. : 2000) 10, 2021 | Pubmed ID: 34498354
Chick cranial neural crest cells release extracellular vesicles critical for their migration.
Journal of cell science May, 2022 | Pubmed ID: 35635292
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