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Center for Data Driven Discovery in Biomedicine
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Overcoming resistance to single-agent therapy for oncogenic gene fusions combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.
Oncotarget Oct, 2017 | Pubmed ID: 29156677
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.
Journal for immunotherapy of cancer Sep, 2022 | Pubmed ID: 36167467
Discovery and functional characterization of the oncogenicity and targetability of a novel gene fusion in pediatric angiosarcoma.
Cold Spring Harbor molecular case studies Oct, 2022 | Pubmed ID: 36307212
Children’s Hospital of Philadelphia
Kyra Harvey1,
Peter J. Madsen2,3,
Tiffany Smith2,
Crystal Griffin1,2,
Luke Patterson1,2,
Nicholas A. Vitanza4,5,
Phillip B. Storm2,3,
Adam C. Resnick2,3,
Jessica B. Foster1,2
1Division of Oncology, Children’s Hospital of Philadelphia,
2Center for Data Driven Discovery in Biomedicine, Children’s Hospital of Philadelphia,
3Division of Neurosurgery, Children’s Hospital of Philadelphia,
4Ben Towne Center for Childhood Cancer Research, Seattle Children’s Research Institute,
5Department of Pediatrics, Seattle Children’s Hospital, University of Washington
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