Moses V. Chao

Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors.

Neurotrophins: to cleave or not to cleave.

Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides.

Lack of the cell-cycle inhibitor p27Kip1 results in selective increase of transit-amplifying cells for adult neurogenesis.

Annexin II light chain regulates sensory neuron-specific sodium channel expression.

Akt1 regulates a JNK scaffold during excitotoxic apoptosis.

Neurotrophins and their receptors: a convergence point for many signalling pathways.

JNK-interacting protein 1 promotes Akt1 activation.

Retrograde transport redux.

Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor.

Telomerase activity in the subventricular zone of adult mice.

Dependence receptors: what is the mechanism?

Motors, adaptors, and receptors: key elements of neuronal transport.

Mechanisms of neurotrophin receptor vesicular transport.

Prevention of apoptotic but not necrotic cell death following neuronal injury by neurotrophins signaling through the tyrosine kinase receptor.

A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrkA receptor.

The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E.

Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration.

Structural biology. The p75 NGF receptor exposed.

A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein.

Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes.

Ternary complex with Trk, p75, and an ankyrin-rich membrane spanning protein.

Neurotrophin survival signaling mechanisms.

Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains.

Axonal growth: where neurotrophins meet Wnts.

{alpha}-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner.

MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth.

Neuregulin-1 type III determines the ensheathment fate of axons.

Biochemical characterization of intracellular membranes bearing Trk neurotrophin receptors.

Identification of a switch in neurotrophin signaling by selective tyrosine phosphorylation.

Neurotrophin signalling in health and disease.

Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons.

Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination.

Promoting neurotrophic effects by GPCR ligands.

BDNF-mediated neurotransmission relies upon a myosin VI motor complex.

A role for Fyn in Trk receptor transactivation by G-protein-coupled receptor signaling.

Pro-NGF secreted by astrocytes promotes motor neuron cell death.

TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain.

Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cgamma signaling pathways in mouse brain.

Neurotrophins, synaptic plasticity and dementia.

The tyrosine kinase Fyn determines the localization of TrkB receptors in lipid rafts.

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway.

Developmental and activity-dependent regulation of ARMS/Kidins220 in cultured rat hippocampal neurons.

Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB.

Stable isotopic labeling by amino acids in cultured primary neurons: application to brain-derived neurotrophic factor-dependent phosphotyrosine-associated signaling.

Variant brain-derived neurotrophic factor (Val66Met) alters adult olfactory bulb neurogenesis and spontaneous olfactory discrimination.

Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effect.

Dopamine D1 receptor-induced signaling through TrkB receptors in striatal neurons.

Ankyrin-rich membrane spanning protein plays a critical role in nuclear factor-kappa B signaling.

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease.

Essential role of Hrs in endocytic recycling of full-length TrkB receptor but not its isoform TrkB.T1.

Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo.

Spongiform pathology in mouse CNS lacking 'neuropathy target esterase' and cellular prion protein.

Neuropathy target esterase is required for adult vertebrate axon maintenance.

A conversation with Rita Levi-Montalcini.

Proneurotrophin-3 is a neuronal apoptotic ligand: evidence for retrograde-directed cell killing.

Nuclear localization of the p75 neurotrophin receptor intracellular domain.

Trk activation in the secretory pathway promotes Golgi fragmentation.

A role for huntington disease protein in dendritic RNA granules.

Trophic factors: 50 years of growth.

Organophosphates induce distal axonal damage, but not brain oedema, by inactivating neuropathy target esterase.

Ira B. Black 1941-2006.

Role of transverse bands in maintaining paranodal structure and axolemmal domain organization in myelinated nerve fibers: effect on longevity in dysmyelinated mutant mice.

Localization of BDNF mRNA with the Huntington's disease protein in rat brain.

The ARMS/Kidins220 scaffold protein modulates synaptic transmission.

Activation of adenosine A2A receptors induces TrkB translocation and increases BDNF-mediated phospho-TrkB localization in lipid rafts: implications for neuromodulation.

The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus.

Transactivation of Trk receptors in spinal motor neurons.

Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression.

Increasing the specificity of neurotrophic factors.

SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in Mammals.

Ankyrin repeat-rich membrane spanning/Kidins220 protein interacts with mammalian Septin 5.

The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching.

Regulation of inhibitory neurotransmission by the scaffolding protein ankyrin repeat-rich membrane spanning/kinase D-interacting substrate of 220 kDa.

The ankyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein is regulated by activity-dependent calpain proteolysis and modulates synaptic plasticity.

Nature and duration of growth factor signaling through receptor tyrosine kinases regulates HSV-1 latency in neurons.

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling.

Regulation of trafficking of activated TrkA is critical for NGF-mediated functions.

Study of neurotrophin-3 signaling in primary cultured neurons using multiplex stable isotope labeling with amino acids in cell culture.

A selective role for ARMS/Kidins220 scaffold protein in spatial memory and trophic support of entorhinal and frontal cortical neurons.

Distribution of phosphorylated TrkB receptor in the mouse hippocampal formation depends on sex and estrous cycle stage.

Paranodal permeability in "myelin mutants".

APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.

TrkB as a potential synaptic and behavioral tag.

Cultured vestibular ganglion neurons demonstrate latent HSV1 reactivation.

Identifying transient protein-protein interactions in EphB2 signaling by blue native PAGE and mass spectrometry.

Spatial segregation of BDNF transcripts enables BDNF to differentially shape distinct dendritic compartments.

Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.

A cell culture model of facial palsy resulting from reactivation of latent herpes simplex type 1.

BDNF Val66Met Impairs Fluoxetine-Induced Enhancement of Adult Hippocampus Plasticity.

BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus.

Huntingtin mediates dendritic transport of β-actin mRNA in rat neurons.

Reversal of Impaired Hippocampal Long-Term Potentiation and Contextual Fear Memory Deficits in Angelman Syndrome Model Mice by ErbB Inhibitors.

Transient Reversal of Episome Silencing Precedes VP16-Dependent Transcription during Reactivation of Latent HSV-1 in Neurons.

The BDNF Val66Met Polymorphism Impairs Synaptic Transmission and Plasticity in the Infralimbic Medial Prefrontal Cortex.