Jan Rupp

First-choice antibiotics at subinhibitory concentrations induce persistence of Chlamydia pneumoniae.

Endothelial Chlamydia pneumoniae infection promotes oxidation of LDL.

Alveolar epithelial cells type II are major target cells for C. pneumoniae in chronic but not in acute respiratory infection.

Cox-2 inhibition abrogates Chlamydia pneumoniae-induced PGE2 and MMP-1 expression.

Asymptomatic carotid atherosclerosis is associated with circulating chlamydia pneumoniae DNA in younger normotensive subjects in a general population survey.

Serine-to-asparagine substitution in the GyrA gene leads to quinolone resistance in moxifloxacin-exposed Chlamydia pneumoniae.

Transmission of Chlamydia pneumoniae infection from blood monocytes to vascular cells in a novel transendothelial migration model.

Chlamydia pneumoniae infection promotes a proliferative phenotype in the vasculature through Egr-1 activation in vitro and in vivo.

Growth cycle-dependent pharmacodynamics of antichlamydial drugs.

The interleukin-6 -174 promoter polymorphism is associated with extrapulmonary bacterial dissemination in Streptococcus pneumoniae infection.

Chlamydophila pneumoniae. Mechanisms of target cell infection and activation.

Critical investigation of the CD14 promoter polymorphism: lack of a role for in vitro cytokine response and membrane CD14 expression.

Tissue microarrays from HOPE-fixed specimens allow for enhanced high throughput molecular analyses in paraffin-embedded material.

Single-nucleotide-polymorphism-specific PCR for quantification and discrimination of Chlamydia pneumoniae genotypes by use of a "locked" nucleic acid.

Be aware of the possibility of false-positive results in single-locus PCR assays for methicillin-resistant Staphylococcus aureus.

Perfluorocarbons decrease Chlamydophila pneumoniae-mediated inflammatory responses of rat type II pneumocytes in vitro.

Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease.

Chlamydia pneumoniae directly interferes with HIF-1alpha stabilization in human host cells.

Prevalence, genetic conservation and transmissibility of the Chlamydia pneumoniae bacteriophage (phiCpn1).

Genetic diversity of the obligate intracellular bacterium Chlamydophila pneumoniae by genome-wide analysis of single nucleotide polymorphisms: evidence for highly clonal population structure.

Variation in the mutation frequency determining quinolone resistance in Chlamydia trachomatis serovars L2 and D.

Experimental induction and three-dimensional two-photon imaging of conjunctiva-associated lymphoid tissue.

Immunoproteomic identification and serological responses to novel Chlamydia pneumoniae antigens that are associated with persistent C. pneumoniae infections.

Modulation of the inflammatory response to Streptococcus pneumoniae in a model of acute lung tissue infection.

159C>T CD14 genotype--functional effects on innate immune responses in term neonates.

Immunomodulatory effects of Sanglifehrin A in the innate and acquired immune response of neonatal whole blood cells.

Chlamydia pneumoniae hides inside apoptotic neutrophils to silently infect and propagate in macrophages.

Proliferative stimulation of the vascular Endothelin-1 axis in vitro and ex vivo by infection with Chlamydia pneumoniae.

The CD40-CD40L pathway contributes to the proinflammatory function of intestinal epithelial cells in inflammatory bowel disease.

Chlamydia pneumoniae-induced memory CD4+ T-cell activation in human peripheral blood correlates with distinct antibody response patterns.

Chlamydia pneumoniae infection and Alzheimer's disease: a connection to remember?

The TGF-beta-pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae.

Divergent modulation of Chlamydia pneumoniae infection cycle in human monocytic and endothelial cells by iron, tryptophan availability and interferon gamma.

The T-helper cell type 1 immune response to gram-negative bacterial infections is impaired in COPD.

Hypoxia abrogates antichlamydial properties of IFN-γ in human fallopian tube cells in vitro and ex vivo.

Impact of a low-oxygen environment on the efficacy of antimicrobials against intracellular Chlamydia trachomatis.

Fluorescence lifetime imaging unravels C. trachomatis metabolism and its crosstalk with the host cell.

Targeting of a chlamydial protease impedes intracellular bacterial growth.

When oxygen runs short: the microenvironment drives host-pathogen interactions.

Association between azithromycin therapy and duration of bacterial shedding among patients with Shiga toxin-producing enteroaggregative Escherichia coli O104:H4.